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committee

Members

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DR. Paul C. Chikezie

Research Scientist

DR. PAUL C. CHIKEZIE is a Research Scientist/Lecturer at the Department of Biochemistry, Imo State University, Owerri, Nigeria. DR. PAUL C. CHIKEZIE holds a Bachelor of Science (B.Sc.) degree in Biochemistry, Masters of Science (M.Sc.) degree in Medical Biochemistry/Immunochemistry and Doctor of Philosophy (Ph.D.) degree in Medical Biochemistry, as well as Certificate in Advanced Digital Appreciation. DR. PAUL C. CHIKEZIE has over seventeen (17) years of research and cognitive experience in the academia with one hundred and two (103) scholarly publications, which include scientific articles in reputable international and local learned journals, as well as edited books and book chapter contributions. DR. PAUL C. CHIKEZIE’s research interests encompass clinical enzymology/toxicology, oxidative stress, phytomedicine, food chemistry/nutritional biochemistry, polyphenol oxidases and hemoglobinopathies with emphasis on sickle cell anemias

1. Clinical Enzymology/Toxicology

2. Haemoglobinopathies

3. Enzymatic Browning Reactions/Food Chemistry

4. Phytomedicine

  

Member, Nigerian Society of Biochemistry and Molecular Biology (NSBMB).

Member, University of Port Harcourt Alumni Association. Port Harcourt, Nigeria.

Member, Research Board of Advisors, American Biographical Institute, USA.

Member, Academic Staff Union of Nigerian Universities

1.Journal of Chemical and Pharmaceutical Research (ISSN: 0975 – 7384).  
2. Current Research in Complementary and Alternative Medicine (ISSN: 2577 – 2201).  3. Journal of Nutrition and Human Health 
4. Lawrence Press.  
5. Madridge Journal of Diabetes 
6. Henry Journal of Diabetes & Metabolic Syndrome 
7. Diabetes and Obesity International Journal (DOJ). 
8. Journal of Basic Pharmacology and Toxicology. 
9. International Journal of Current Research
10. Sumerians Journal of Biotechnology. 
 

1. Chikezie, C.M., Ojiako, A.O., Emejulu, A.A. and Chikezie, P.C. (2018). Atherogenicity of diabetic rats
administered single and combinatorial herbal extracts. Bulletin of Faculty of Pharmacy, 
Cairo University. (In Press: Manuscript №: BFOPCU-D-18-00040R1).  
2. Chikezie, C.M., Ojiako, A.O., Emejulu, A.A. and Chikezie, P.C. (2018). Single and combinatorial herbal
extracts ameliorate hyperglycemia and dyslipidemia in diabetic rats. AYU (An 
International Quarterly Journal of Research in Ayurveda).  (In Press: Manuscript №: AYU_2_18).

3. Chikezie, P.C., Ezeocha, B.C. and Nwankpa, P. (2018). Changes in hepato-renal tissues biomarkers
of alloxan-induced diabetic Wistar rats co-administered monosodium glutamate and
ascorbic acid. MOJ Food Processing & Technology. 6(3), 312‒317. ISSN: 2381-182X. DOI: 
10.15406/mojfpt.2018.06.00181. Available from: 
http://medcraveonline.com/MOJFPT/MOJFPT-06-00181.pdf 
http://medcraveonline.com/MOJFPT/current-issue 
http://medcraveonline.com/article?id=15336

4. Nwankpa, P., Etteh, C.C., Ekweogu, C.N., Chikezie, P.C., Chukwuemeka O.G., and Egwurugwu 
J.N. (2018). Effect of ethanol root and leave extracts of Sida acuta on some kidney function indices
and electrolytes in albino Wistar rats. International Journal of Current Microbiology and 
Applied Sciences. 7(2), 2759-2766. ISSN: 2319-7706. DOI: 10.20546/ijcmas.2018.702.336. 
Available from: 
https://www.ijcmas.com/7-2-2018/P.%20Nwankpa,%20et%20al.pdf 
https://www.ijcmas.com/abstractview.php?ID=6714&vol=7-2-2018&SNo=336 
https://www.ijcmas.com/feb2018issue.php

5. Ojiako, A.O., Chikezie, P.C., Ukairo, D.I., Ibegbulem, C.O. and Nwaoguikpe, R.N. (2018). Hepatic oxidative stress and hematological parameters of Wistar rats following infusion of carbon tetrachloride
and treated with raw and hydrothermal processed herbs. Pharmacognosy 
Communications. 8(1), 29-36. ISSN: 2249-0159 (Print); 2249-0167 (Online). DOI: 
10.5530/pc.2017.3.19. Available from:  
http://www.phcogcommn.org/content/153 
http://www.phcogcommn.org/sites/default/files/PharmaComm_8_1_29.pdf 
http://phcogcommn.org/frontpage

6. Chikezie, C.M., Ojiako, A.O., Emejulu, A.A. and Chikezie, P.C. (2018). Serum lactate dehydrogenase
activity and visceral organs and body weights of diabetic rats administered single
and combinatorial herbal formulations. Pharmacognosy Communications. 8(1), 37-42. 
ISSN: 2249-0159 (Print); 2249-0167 (Online). DOI: 10.5530/pc.2017.3.19. Available from: 
http://www.phcogcommn.org/content/154 
http://www.phcogcommn.org/sites/default/files/PharmaComm_8_1_37.pdf 
http://phcogcommn.org/frontpage

7. Ibegbulem, C.O., and Chikezie, P.C. (2018). Comparative proximate composition and cyanide content
of peeled and unpeeled cassava tubers processed into garri by traditional methods. 
Research Journal of Food and Nutrition. 2(1), 1-13. Available from: 
www.sryahwapublications.com

8. Ibegbulem, C.O., Ene, A.C., Nwanpka, P., Chikezie, P.C. and Igwe, C.U. (2017). Effect of wood 
charcoal on a rate of microbial production of lactic acid in dehulled and undehulled Vigna 
unguiculata pastes. Journal of Nutrition and Food Sciences. 7(2), 4 pages. ISSN: 2155-9600. DOI: 
10.4172/2155-9600.1000587. Available from: 
http://dx.doi.org/10.4172/2155-9600.1000587 
https://www.omicsonline.org/ArchiveJNFS/currentissue-nutrition-food-sciences-open
access.php 
https://www.omicsonline.org/open-access/effect-of-wood-charcoal-po... 
https://www.omicsonline.org/peer-reviewed/effect-of-wood-charcoal-powder-on-rate-of
microbial-production-of-lactic-acid-in-dehulled-and-undehulled-vigna-unguiculata-pastes
87336.html

9. Ojiako, A.O., Chikezie, P.C., Ukairo, D.I., Ibegbulem, C.O. and Nwaoguikpe R.N. (2017). 
Functional assessments and histopathology of hepatorenal tissues of Wistar rats infused with carbon
tetrachloride and treated with raw and hydrothermal processed herbs. Pharmacognosy 
Communications. 7(4), 142-151. ISSN: 2249-0159 (Print); 2249-0167 (Online). DOI: 
10.5530/pc.2017.4.21. Available from:  
http://phcogcommn.org/content/142 
http://phcogcommn.org/frontpage 
http://www.phcogcommn.org/tags/hydrothermal

10. Ezekwe, S.A. and Chikezie, P.C. (2017). GC-MS analysis, the hypoglycemic activity of aqueous root extract of Carica papaya and its effects on blood lipid profile and hepatorenal tissues biomarkers
of diabetic rats. Journal of Diabetes and Metabolism. 8(5):508, 9 pages. ISSN: 2155
6156. DOI: 10.4172/2155-6156.1000740. Available from: 
http://dx.doi.org/10.4172/2155-6156.1000740 
https://www.omicsonline.org/peer-reviewed/gcms-analysis-hypoglycemic-activity-of-aqueous
root-extract-of-Carica papaya-and-its-effects-on-blood-lipid-profile-and-hepatorenal
88800.html 
https://www.omicsonline.org/open-access/gcms-analysis-hypoglycemic-activity-of-aqueous
root-extract-of-Carica papaya-and-its-effects-on-blood-lipid-profile-and-hepatorenal-2155
6156-1000740.pdf.

11. Chikezie, P.C., Ezirim, Y.C., Iheanacho, K.M.E., Nwachukwu, R. (2017). Comparative activities of soil enzymes from polluted sites in Egbema, Imo State, Nigeria. Journal of Pollution Effects and 
Control. 5(2), 7 pages. ISSN: 2375-4397. DOI: 10.4172/2375-4397.1000185. Available from: 
https://www.omicsonline.org/open-access/comparative-activities-of-soil-enzymes-from
polluted-sites-in-edema-IMO state-Nigeria-2375-4397-1000185.pdf 
https://www.omicsonline.org/peer-reviewed/comparative-activities-of-soil-enzymes-from
polluted-sites-in-edema-imornstate-Nigeria-90451.html.

12. Ezekwe, S.A. and Chikezie, P.C. (2017). GC-MS analysis of an aqueous extract of the unripe fruit of 
Carica papaya. Journal of Nutrition and Food Sciences. 7(3), 5 pages. ISSN: 2155-9600. DOI: 
10.4172/2155-9600.1000602. Available from: 
http://dx.doi.org/10.4172/2155-9600.1000602 
https://www.omicsonline.org/open-access/gcms-analysis-of-aqueous-extract-of-unripe-fruit
of-Carica-papaya-2155-9600-1000602.pdf 
https://www.omicsonline.org/ArchiveJNFS/currentissue-nutrition-food.

13. Chikezie, P.C. (2016). Total phenolic contents and antioxidant potential of soya bean and maize and
their beverages in vitro. Journal of Nutritional Disorders and Therapy. 6:198. 7 pages. ISSN: 
2161-0509. DOI: 10.4172/2161-0509.1000198. Available from: 
http://www.omicsonline.org/open-access/total-phenolic-contents-and-anti... 
http://www.omicsonline.org/open-access/total-phenolic-contents-and-antioxidant-potential
of-soya-bean-and-maize and-their-beverages-in-vitro-2161-0509-1000198.pdf

14. Chikezie, P.C., Ibegbulem, C.O., Monago, O.S., Mbagwu, F.N. and Nwachukwu, C.U. (2016). 
Amino acid profiles, total nitrogen contents and computed-protein efficiency ratios of Manihot 
esculenta root and Dioscorea rotundata tuber peels. Journal of Food Processing. 2016(2016), 
Article ID 1697458, 8 pages. ISSN: 2356-7384 (Print); ISSN: 2314-839X (Online). DOI: 
10.1155/2016/1697458. Available from:    
http://dx.doi.org/10.1155/2016/1697458 
https://www.hindawi.com/journals/jfp/2016/1697458/ 
https://www.hindawi.com/journals/jfp/2016/1697458/abs/ 
https://www.hindawi.com/journals/jfp/contents/

15. Chikezie, P.C. (2016). Membrane lipid peroxidation and redox status in erythrocytes of sickle 
cell anaemia patients incubated in leaf extract of Gongronema latifolium. Journal of 
Experimental and Integrative Medicine. 6(2), 57-65. ISSN: 1309-4572 (Print); ISSN: 2146-3298 
(Online). DOI: 10.5455/jeim.210616.or.151. Available from:   
http://www.scopemed.org/?mno=226046 
http://www.scopemed.org/fulltextpdf.php?mno=226046 
http://www.ejmanager.com/mnstemps/4/4-1461153054.pdf?t=1473176666 
http://www.scopemed.org/?jid=4&lng=

16. Chikezie, P.C. and Ekechukwu, C.U. (2016). Acute patho-toxicological indicators of 
methaemoglobinemia. Journal of Acute Disease. 5(3), 179-184. ISSN: 2221-6189. DOI: 
10.1016/j.joad.2016.03.001. Available from: 
www.jadweb.org 
http://dx.doi.org/10.1016/j.joad.2016.03.001 
http://www.sciencedirect.com/science/article/pii/S2221618916300142 
http://ac.els-cdn.com/S2221618916300142/1-s2.0-S2221618916300142
main.pdf?_tid=6bf09702-1814-11e6-b190
00000aacb361&acdnat=1463038847_d403ae6ee3ea66f0c49b88332926c2c7 
http://ac.els-cdn.com/S2221618916300142/1-s2.0-S2221618916300142
main.pdf?_tid=e3e9a428-fa29-11e5-9785
00000aab0f6c&acdnat=1459749532_c2d77548635bc95823afc3fc12ca9846

17. Ojiako, A.O., Chikezie, P.C. and Ogbuji, C.A. (2016). Radical scavenging potentials of single and combinatorial herbal formulations in vitro. Journal of Traditional and Complementary Medicine. 
6(2016), 153-159. ISSN: 2225-41100. DOI: 10.1016/j.jtcme.2014.11.037. Available from:   
http://www.elsevier.com/locate/jtcme  
http://dx.doi.org/10.1016/j.jtcme.2014.11.037 
http://www.sciencedirect.com/science/article/pii/S2225411014000510 
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4833459/ 
http://ac.els-cdn.com/S2225411014000510/1-s2.0-S2225411014000510
main.pdf?_tid=8a9a6388-fcfb-11e5-83db
00000aacb35f&acdnat=1460059479_ce619bc9c30ff5b3fb79da974ad6a3cd

18. Ojiako, A.O., Chikezie, P.C. and Ogbuji, C.A. (2016). Blood glucose level and lipid profile of 
alloxan-induced hyperglycemic rats treated with single and combinatorial herbal formulations. 
Journal of Traditional and Complementary Medicine. 6(2), 184-192. ISSN: 2225-41100. DOI: 
10.1016/j.jtcme.2014.12.005. Available from:   
http://www.elsevier.com/locate/jtcme 
http://dx.doi.org/10.1016/j.jtcme.2014.12.005 
http://www.sciencedirect.com/science/article/pii/S2225411014000601 
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4833464/ 
http://ac.els-cdn.com/S2225411014000601/1-s2.0-S2225411014000601
main.pdf?_tid=ba85d172-fcfb-11e5-be08
00000aacb362&acdnat=1460059560_35d5be90688d59dc9713bdcd09a56058

19. Ibegbulem, C.O. and Chikezie, P.C. (2016). Levels of acute blood indices disarrangement and 
organ weights of Wistar rats fed with flavour enhancer- and contraceptive-containing diets. 
Journal of Investigational Biochemistry. 5(1), 1-9. ISSN: 2146-8338 (Print). DOI: 
10.5455/jib.20160106122902. Available from: 
http://www.scopemed.org/?mno=208407 
http://www.scopemed.org/fulltextpdf.php?mno=208407 
http://www.ejmanager.com/mnstemps/61/61-1447843185.pdf?t=1461389105 
http://www.scopemed.org/?iid=2016-5&&jid=61&lng= 
 20. Ibegbulem, C.O., Chikezie, P.C., Ukoha, A.I. and Opara, C.N. (2016). Effects of diet containing 
monosodium glutamate on organ weights, acute blood steroidal sex hormone levels, lipid 
profile and erythrocyte antioxidant enzymes activities of rats. Journal of Acute Disease. 5(5), 
402-407. ISSN: 2221-6189. DOI: 10.1016/j.joad.2016.08.007. Available from:  
http://dx.doi.org/10.1016/j.joad.2016.08.007 
www.jadweb.org 
http://www.sciencedirect.com/science/article/pii/S2221618916301135 
https://authors.elsevier.com/offprints/JOAD139/d71f77df16711fd26cef7fdf305fb41f  
http://ac.els-cdn.com/S2221618916301135/1-s2.0-S2221618916301135
main.pdf?_tid=ab364a8c-8809-11e6-81c9
00000aab0f6b&acdnat=1475348759_df26aee8604ca8b0cfd261c083646518

21. Ibegbulem, C.O., Chikezie, P.C. and Dike E.C. (2016). Pathological research on acute hepatic and renal tissue damage in Wistar rats induced by cocoa. Journal of Acute Disease. 5(1), 51–58. 
ISSN: 2221-6189. DOI: 10.1016/j.joad.2015.07.005. Available from: 
http://dx.doi.org/10.1016/j.joad.2015.07.005 
http://www.sciencedirect.com/science/article/pii/S2221618915000864 
http://www.sciencedirect.com/science/journal/22216189/5/1

22. Ojiako, A.O., Chikezie, P.C., Ukairo, D.I., Ibegbulem, C.O. and Nwaoguikpe, R.N. (2016). Radical scavenging potentials: Vitamin-derived antioxidants and total phenolic contents of raw and hydrothermal
processed herbs in vitro. Journal of Experimental and Integrative Medicine. 6(4), 
158-167. ISSN: 1309-4572 (Print); ISSN: 2146-3298 (Online). DOI: 10.5455/jeim.191016.or.162. 
Available from: 
http://www.jeim.org/?sec=cissue 
http://www.ejmanager.com/fulltextpdf.php?mno=235798 
http://www.ejmanager.com/mnstemps/4/4-1468416028.pdf?t=1481126328

23. Chikezie, P.C., Ibegbulem, C.O. and Mbagwu, F.N. (2015). Bioactive principles from medicinal 
plants. Research Journal of Phytochemistry. 9(3), 88-115. ISSN: 1819-3471. DOI: 
10.3923/rjphyto.2015.88.115. Available from: 
http://scialert.net/abstract/?doi=rjphyto.2015.88.115 
http://scialert.net/fulltext/?doi=rjphyto.2015.88.115&org=10 
http://www.scialert.com/ems/qredirect.php?linkid=pdf&doi=rjphyto.2015.88.115

24. Ojiako, A.O., Chikezie, P.C. and Ogbuji, C.A. (2015). Glycemic index/renal and hepatic 
antioxidant status of hyperglycemic rats treated with single and combinatorial herbal formulations
. Journal of Diabetes and Metabolism. 6(3):508, 10 pages. ISSN: 2155-6156 JDM. 
DOI: 10.4172/2155-6156.1000508. Available from:   
http://dx.doi.org/10.4172/2155-6156.1000508 
http://www.omicsonline.org/open-access/glycemic-indicesrenal-and-he... 
http://www.omicsonline.org/open-access/glycemic-indicesrenal-and-hepatic-antioxidant
status-of-hyperglycemic-rats-treated-with-single-and-combinatorial-herbal-formulations-2155
6156.1000508.pdf.php?aid=40779

25. Chikezie, P.C., Ojiako, A.O. and Ogbuji, C.A. (2015). Oxidative stress in diabetes mellitus. 
International Journal of Biological Chemistry. 9(3), 92-109. ISSN: 1819-155X. DOI: 
10.3923/ijbc.2015.92.109. Available from:  
http://www.scialert.net/abstract/?doi=ijbc.2015.92.109 
http://www.scialert.net/current.php?issn=1819-155x 
http://www.scialert.net/qredirect.php?doi=ijbc.2015.92.109&linkid=pdf 
http://scialert.net/archivedetails.php?issn=1819-155x&issueno=32 
http://scialert.net/fulltext/?doi=ijbc.2015.92.109&org=10

26. Chikezie, P.C. and Ojiako, A.O. (2015). Herbal medicine: yesterday, today and tomorrow. 
Alternative and Integrative Medicine. 4(3):195, 5 pages. ISSN: 2327-5162 AIM. DOI: 
10.4172/2327-5162.1000195. Available from:  
http://www.omicsgroup.org/journals/internal-medicine-abstract.php?abstract_id=58504 
http://www.esciencecentral.org/journals/herbal-medicine-yesterday-today-and-tomorrow
2327-5162-1000195.php?aid=58504 
http://dx.doi.org/10.4172/2327-5162.1000195

27. Ojiako, A.O. and Chikezie, P.C. (2015). Blood Na+/K+ and Cl- levels of hyperglycemic rats 
administered with traditional herbal formulations. Pharmacognosy Communications. 5(2), 140
144. ISSN: 2249-0159 (Print); 2249-0167 (Online). DOI: 10.5530/pc.2015.2.5. Available from:  
http://phcogfirst.com/article/1310 
www.phcogcommn.org 
http://www.phcogfirst.com/article/1310  
http://www.scopemed.org/?jid=66&lng=

28. Ojiako, A.O., Chikezie, P.C. and Ogbuji, C.A. (2015). Histopathological studies of renal and 
hepatic tissues of hyperglycemic rats administered with traditional herbal formulations. 
International Journal of Green Pharmacy. 9(3), 184-191. ISSN: 0973-8258. DOI: 10.4103/0973
8258.161237. Available from: 
www.greenpharmacy.info  
http://www.greenpharmacy.info/text.asp?2015/9/3/184/161237 
http://www.greenpharmacy.info/article.asp?issn=0973-8258;year=2015...  
http://www.greenpharmacy.info/currentissue.asp?sabs=

 29. Ojiako, A.O., Chikezie, P.C. and Ogbuji, C.A. (2015). Antioxidant status of liver and kidney homogenates
from hyperglycemic rats administered with single and combinatorial herbal formulations
. Free Radicals and Antioxidants. 5(1), 13-20. ISSN: 2231-2536. DOI: 
10.5530/fra.2015.1.3. Available from:   
http://www.phcogfirst.com/article/1299 
http://www.phcogfirst.com/sites/default/files/FRA_5_1_03.pdf

30. Ojiako, A.O., Chikezie, P.C. and Ogbuji, C.A. (2015). Comparative hypoglycemic activities of 
aqueous and ethanolic extracts of four medicinal plants (Acanthus montanus, Asystasia 
gangetica, Emilia coccinea and Hibiscus rosasinensis) in Type I diabetic rats. Journal of 
Intercultural Ethnopharmacology. 4(3), 228-233. ISSN: 2146-8397 (Print). DOI: 
10.5455/jice.20150508045222. Available from:  
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579485/ 
http://www.ncbi.nlm.nih.gov/pubmed?term="J+Intercult+Ethnopharmac... 
http://www.ncbi.nlm.nih.gov/pubmed/26401413  
http://www.scopemed.org/?mno=185188 
http://www.scopemed.org/fulltextpdf.php?mno=185188 
http://www.ejmanager.com/mnstemps/55/55-1429163583.pdf?t=1432102038

31. Chikezie, P.C. (2015). Short-term capacities of ethanolic Theobroma cacao bean extract to 
ameliorate oxidative stress, hyperglycemia and dyslipidemia in alloxan-induced diabetic rats. 
Journal of Investigational Biochemistry. 4(1), 23-29. ISSN: 2146-8338 (Print). DOI: 
10.5455/jib.20150504014936. Available from: 
http://www.scopemed.org/fulltextpdf.php?mno=181930 
http://www.scopemed.org/?mno=181930

32. Chikezie, P.C. (2015). Glutathione S-transferase activity in diagnostic pathology. Metabolomics. 
5(4):153, 8 pages. ISSN: 2153-0769 JOM. DOI: 10.4172/2153-0769.1000153. Available from: 
http://www.omicsonline.org/ArchiveJOM/articleinpress-metabolomics-open-access.php  
http://www.omicsonline.org/open-access/glutathione-stransferase-activity-in-diagnostic
pathology-2153-0769-1000153.php?aid=63182  
http://www.omicsonline.org/open-access/glutathione-stransferase-activi... 
http://dx.doi.org/10.4172/2153-0769.1000153

33. Chikezie, P.C. (2015). Critical roles of thiol-mediated antioxidant detoxification systems in the 
pathophysiology of Plasmodium falciparum-infected erythrocytes. Journal of Investigational 
Biochemistry. 4(3), 61-68. ISSN: 2146-8338 (Print). DOI: 10.5455/jib.20151230060340. Available 
from: 
http://www.scopemed.org/fulltextpdf.php?mno=208252 
http://www.scopemed.org/?mno=208252 
http://www.journaltocs.ac.uk/index.php?action=tocs&journalID=27822 
http://www.scopemed.org/?jid=66&lng=  

34. Ibegbulem, C.O., Chikezie, P.C. and Dike, E.C. (2015). Growth rate, haematologic and 
atherogenic indicators of Wistar rats fed with cocoa beverages. Journal of Molecular 
Pathophysiology. 4(2), 77-84. ISSN: 2146-832X (Print). DOI: 10.5455/jmp.20150623092916. 
Available from:  
http://www.scopemed.org/?jid=66&lng= 
http://www.scopemed.org/?mno=190203 
http://www.scopemed.org/fulltextpdf.php?mno=190203

35. Chikezie, P.C. (2015). Kinetic studies of polyphenol oxidase from white yam (Dioscorea 
rotundata Poir) tuber. Journal of Nutrition and Food Science. 5(2):355, 8 pages. ISSN: 2155
9600 JNFS. DOI: 10.4172/2155-9600.1000355. Available from: 
http://dx.doi.org/10.4172/2155-9600.1000355 
http://omicsonline.org/open-access/kinetic-studies-of-polyphenol-oxidase-from-white-yam
dioscorea-rotundata-poir-tuber-2155-9600-1000355.php?aid=42291 
http://omicsonline.org/open-access/kinetic-studies-of-polyphenol-oxidase-from-white-yam
dioscorea-rotundata-poir-tuber-2155-9600-1000355.pdf

36. Chikezie, P.C., Ojiako, A.O. and Nwufo, K.C. (2015). Overview of anti-diabetic medicinal plants: 
The Nigerian research experience. Journal of Diabetes and Metabolism. 6(6):546, 7 pages. ISSN: 
2155-6156 JDM. DOI: 10.4172/2155-6156.1000546. Available from: 
http://omicsonline.org/diabetes-metabolism-abstract.php?abstract_id=53380 
http://omicsonline.org/open-access/overview-of-antidiabetic-medicinal-plants-the-nigerian
research-experience-2155-6156-1000546.pdf 

 37. Chikezie, P.C. and Iheanacho, K.M.E. (2014). Comparative hypoglycemic property of aqueous 
and ethanolic extracts of Viscum album (Mistletoe) and their effects on body and organ 
weights of diabetic rats (Rattus norvegicus). Pharmacognosy Communications. 4(2), 13-19. 
ISSN: 2249-0159 (Print); 2249-0167 (Online). DOI: 10.5530/pc.2014.2.4. Available from: 
http://www.phcogfirst.com/article/783 
http://www.phcogfirst.com/sites/default/files/PC_4_2_4.pdf

38. Ibegbulem, C.O., and Chikezie, P.C. (2014). Biochemical indices and sensory scores of Kunu-Zaki beverages produced from sprouted and unsprouted guinea corn and their correlations. 
American Journal of Food Technology. 9(1), 56-63. ISSN: 1557-4571; DOI: 
10.3923/ajft.2014.56.62. Available from: 
http://scialert.net/qredirect.php?doi=ajft.2014.56.62&linkid=pdf 
http://scialert.net/fulltext/?doi=ajft.2014.56.62&org=10 
http://scialert.net/abstract/?doi=ajft.2014.56.62

39. Ibegbulem, C.O., Chikezie, P.C., Nweke, C.O., Nwanyanwu, C.E. and Belonwu, D.C. (2014).  
Effects of processing pineapple-based must into wines by anaerobic fermentation. American 
Journal of Food Technology. 9(3), 162-171. ISSN: 1557-4571. DOI: 10.3923/ajft.2014.162.171. 
Available from: 
http://www.scialert.net/qredirect.php?doi=ajft.2014.162.171&linkid=pdf 
http://scialert.net/fulltext/?doi=ajft.2014.162.171&org=10 
http://scialert.net/abstract/?doi=ajft.0000.64018.64018

40. Belonwu, D.C., Ibegbulem, C.O. and Chikezie, P.C. (2014). Systemic evaluation of antibacterial 
activity of Anacardium occidentale. The Journal of Phytopharmacology. 3(3), 193-199. ISSN 
2230-480X. Available from: 
http://www.phytopharmajournal.com/Vol3_Issue3_06.pdf 
www.phytopharmajournal.com 41. Chikezie, P.C. (2014). Glutathione S-transferase activity of three erythrocyte genotypes of 
human participants treated with pyrimethamine/sulphadoxine and quinine. Global Journal of 
Medical Research: B Pharma, Drug Discovery, Toxicology and Medicine. 14(6), 5-12. Online 
ISSN: 2249-4618 & Print ISSN: 0975-5888. Available from: 
https://globaljournals.org/GJMR_Volume14/2-Glutathione-S-Transferase-Activity.pdf 
https://globaljournals.org/GJMR_Volume14/E-Journal_GJMR_%28B%29_Vol_14_Issue_6.pdf https://globaljournals.org/papers/

42. Chikezie, P.C. (2014). Comparative erythrocyte glutathione S-transferase activity profile of non
malarious guinea pigs (Cavia tschudii) administered with pyrimethamine/sulphadoxine and 
artemether/lumefantrine combination therapies. Asian Journal of Biochemistry. 9(4), 203-212.  
ISSN: 1815-9923; DOI: 10.3923/ajb.2014.203.212. Available from: 
http://docsdrive.com/pdfs/academicjournals/ajb/2014/203-212.pdf 
http://scialert.net/fulltext/?doi=ajb.2014.203.212&org=10 
http://scialert.net/abstract/?doi=ajb.2014.203.212

43. Chikezie, P.C. and Uwakwe, A.A. (2014). Activities of three erythrocyte enzymes of 
hyperglycemic rats (Rattus norvegicus) treated with Allium sativa extract. Journal of Diabetes 
and Metabolic Disorders. 13:50, 9 pages. ISSN: 2251-6581. DOI: 10.1186/2251-6581-13-50. 
Available from: 
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031975/ 
http://www.jdmdonline.com/content/pdf/2251-6581-13-50.pdf 
http://www.jdmdonline.com/content/13/1/50

44. Chikezie, P.C. (2014). Membrane integrity of human two erythrocyte genotypes in the 
presence ofthe aqueous solution of sodium metabisulphite and their correlations in vitro. Journal 
of Investigational Biochemistry. 3(4), 164-169. ISSN: 2146-8338 (Print). DOI: 
10.5455/jib.20141030112431. Available from:   
http://www.scopemed.org/?mno=170902 
http://www.scopemed.org/fulltextpdf.php?mno=170902 
http://www.ejmanager.com/mnstemps/61/61-1412275889.pdf?t=1420465876 
 
 45. Chikezie, P.C. and Uwakwe, A.A. (2014). Protective effect of Allium sativa extract against 
carbon tetrachloride-induced hepatic oxidative stress and hyperlipidemia in rats. African 
Journal of Biotechnology. 13(15), 1671-1678. ISSN: 1684-5315. DOI: 10.5897/AJB2013.13338. 
Available from: 
http://www.academicjournals.org/journal/AJB/article-abstract/79C531... 
http://www.academicjournals.org/article/article1397581291_Chidoka%20and%20Amadikwa.pdf 

46. Ojiako, A.O. and Chikezie, P.C. (2014). Comparative proximate composition and hypoglycemic 
properties of three medicinal plants (Verononia amygdalina, Azadirachta indica and Moringa 
oleifera). Pharmacognosy Communications. 4(3), 40-48. ISSN: 2249-0159 (Print); 2249-0167 
(Online). DOI: 10.5530/pc.2014.3.4. Available from: 
http://phcogfirst.com/article/756  
www.phcogcommn.org

47. Alisi, C.S. and Chikezie, P.C. (2014). Assessment of air quality and erythrocyte oxidative stress 
indicators of storekeepers of laboratory/industrial chemicals in Owerri, Imo State, Nigeria. Free 
Radicals and Antioxidants. 4(1), 67-69. ISSN: 2231-2536. DOI: 10.5530/fra.2014.1.11. Available 
from: 
http://www.antiox.org/article/21 
http://www.antiox.org  48. Belonwu, D.C., Ibegbulem, C.O., Nwokocha, M.N. and Chikezie, P.C. (2014). Some 
phytochemicals and hydrophilic vitamins of Anacardium occidentale. Research Journal of 
Phytochemistry. 8(3), 78-91. ISSN: 1819-3471. DOI: 10.3923/rjphyto.2014.78.91. Available 
from:  
http://scialert.net/abstract/?doi=rjphyto.2014.78.91 
http://scialert.net/fulltext/?doi=rjphyto.2014.78.91&org=10 
http://docsdrive.com/pdfs/academicjournals/rjphyto/2014/78-91.pdf

49. Ojiako, A.O., Chikezie, P.C. and Zedech, U.C. (2013). Serum lipid profile of hyperlipidemic 
rabbits (Lepus townsendii) administered with leaf extracts of Hibiscus rosesinesis, Emilia 
coccinea, Acanthus montanus and Asystasia gangetica. Journal of Medicinal Plant Research. 
7(43), 3226-3231. ISSN: 2722-2728. DOI: 10.5897/JMPR2013.5281. Available from: 
http://www.academicjournals.org/journal/JMPR/article-abstract/CFB858241771 
http://www.academicjournals.org/article/article1384439722_Ojiako%20et%20al.pdf

50. Chikezie, P.C., Akuwudike, A.R. and Chikezie, C.M. (2013). Polymerization studies of sickle cell hemoglobin incubated in aqueous leaf extract of Nicotiana tabacum product. Research Journal 
of Medicinal Plants. 7(2), 92-99. ISSN: 1819-3455. DOI: 10.3923/rjmp.2013.92.99. Available 
from:  
http://scialert.net/qredirect.php?doi=rjmp.2013.92.99&linkid=pdf 
http://scialert.net/fulltext/?doi=rjmp.2013.92.99 
http://scialert.net/abstract/?doi=rjmp.0000.50408.50408

51. Chikezie, P.C. and Ojiako, A.O. (2013). Cyanide and aflatoxin loads of processed Cassava 
(Manihot esculenta) tubers (Garri) in Njaba, Imo State, Nigeria. Toxicology International. 20(3), 
261-267. ISSN: 0971-6580. DOI: 10.4103/0971-6580.121679. Available from: 
http://www.ncbi.nlm.nih.gov/m/pubmed/24403736/ 
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877494/ 
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877494/?report=reader 
http://www.toxicologyinternational.com/text.asp?2013/20/3/261/121679 
http://www.toxicologyinternational.com/article.asp?issn=09716580;year=2013;volume=20;iss
ue=3;spage=261;epage=267;aulast=Chikezie;type=0 
http://www.toxicologyinternational.com/article.asp?issn=09716580;year=2013;volume=20;iss
ue=3;spage=261;epage=267;aulast=Chikezie

52. Chikezie, P.C., Akuwudike, A.R., Chikezie, C.M. and Ibegbulem, C.O. (2013). Fractional 
purification and kinetic parameters (Km and Vmax) of polyphenol oxidase extracted from three 
segments of Solanum melongenas and Musa sapientum fruits. American Journal of Plant 
Physiology. 8(2), 63-73. ISSN: 1557-4539. DOI: 10.3923/ajpp.2013.63.73. Available from: 
http://scialert.net/qredirect.php?doi=ajpp.2013.84.92&linkid=pdf 
http://scialert.net/fulltext/?doi=ajpp.2013.84.92&org=10 
http://scialert.net/abstract/?doi=ajpp.0000.50820.50820

53. Chikezie, P.C., Akuwudike, A.R. and Chikezie, C.M. (2013). Thermal and pH stabilities of 
polyphenol oxidase extracted from Solanum melongenas and Musa sapientum fruits. African 
Journal of Biotechnology. 12(38), 5688-5694. ISSN: 1684-5315. DOI: 10.5897/AJB2013.12353. 
Available from: 
http://vvww.academicjournals.org/journal/AJB/article-abstract/5490D8626505 
http://www.academicjournals.org/article/article1380785108_Chikezie%20et%20al.pdf

54. Akuwudike, A.R., Chikezie, P.C. and Chilaka, F.C. (2013). Absorption spectra of normal adults 
and patients with sickle cell anemia haemoglobins treated with hydrogen peroxide at two pH 
values. Iranian Journal of Blood and Cancer (IJBC). 5(4), 129-135. ISSN: 2008-4595. Available 
from: 
http://www.ijbc.ir/browse.php?a_id=416&sid=1&slc_lang=fa 
http://ijbc.ir/browse.php?a_id=416&sid=1&slc_lang=en 

55. Chikezie, P.C. and Okpara, R.T. (2013).  Serum lipid profile and hepatic dysfunction in moderate 
Plasmodium falciparum infection.  Journal of Public Health and Epidemiology. 5(9), 379-384. 
ISSN: 2006-9723. DOI: 10.5897/JPHE2013.0545. Available from: 
http://www.academicjournals.org/journal/JPHE/article-abstract/6D1FEA55388 
http://www.academicjournals.org/article/article1379692633_Chikezie%20%20and%20Okpara.
pdf

56. Chikezie, P.C. and Okpara, R.T. (2013). Haematologic and biochemical indices of Plasmodium 
falciparum infected inhabitants of Owerri, Imo State, Nigeria. Journal of Medical Laboratory 
and Diagnosis. 4(5), 38-44. ISSN: 2141-2618. DOI: 10.5897/JMLD2013-0068. Available from: 
http://www.academicjournals.org/journal/JMLD/article-stat/61127DB1147 
http://www.oxfordjournals.academicjournals.org/journal/JMLD/article-abstract/61127DB1147 
http://www.academicjournals.org/article/article1379418291_Chikezie%20and%20Okpara.pdf

57. Ibegbulem, C.O. and Chikezie, P.C. (2013). Hypoglycemic properties of ethanolic extracts of 
Gongronema latifolium, Aloe perryi, Viscum album and Allium sativum administered to alloxan
induced diabetic albino rats (Rattus norvegicus). Pharmacognosy Communications. 3(2), 12-16. 
ISSN: 2249-0159 (Print); 2249-0167 (Online). DOI: 10.5530/pc.2013.2.4. Available from: 
http://www.phcogfirst.com/article/809 
http://www.phcogfirst.com/sites/default/files/PC_3_2_4.pdf

58. Ibegbulem, C.O. and Chikezie, P.C. (2012). Serum lipid profile of rats (Rattus norvegicus) fed 
with palm oil and palm kernel oil-containing diets. Asian Journal of Biochemistry. 7(1), 46-53. 
ISSN: 1815-9923. DOI: 10.3923/ajb.2012.46.53. Available from: 
http://scialert.net/fulltext/?doi=ajb.2012.46.53 
http://scialert.net/abstract/?doi=ajb.2012.46.53

59. Ibegbulem, C.O., Nwaogu, L.A., Alisi, C.S., Igwe, C.U., Egbung, G.E. and Chikezie, P.C. (2012). 
Anti-aggregation effects of processed yellow and white garri aqueous filtrates on sickle cell trait 
haemoglobin. Journal of Research in Biochemistry. 1(1), 047-052. ISSN: BC0005. Available from: 
https://www.researchgate.net/publication/256662483_Antiaggregation_effects_of_processed
_yellow_and_white_Garri_Aqueous_Filtrates_on_sickle_cell_Trait_Haemoglobin\

60. Chikezie, P.C., Akuwudike, A.R. and Chikezie, C.M. (2012). Membrane stability and 
methaemoglobin content of human erythrocytes incubated in aqueous leaf extract of Nicotiana 
tabacum product. Free Radicals and Antioxidants. 2(4), 56-61. ISSN: 2231-2536. DOI: 
10.5530/ax.2012.4.10. Available from: 
http://dx.doi.org/10.5530/ax.2012.4.10  
http://www.sciencedirect.com/science/article/pii/S223125361224010X 
http://linkinghub.elsevier.com/retrieve/pii/S223125361224010X?via=sd 
http://www.sciencedirect.com/science?_ob=ArticleListURL&_method=l.

61. Chikezie, P.C. (2011). Methaemoglobin concentration and NADH-methaemoglobin reductase 
activity of three human erythrocyte genotypes. Asian Journal of Biochemistry. 6(1), 98-103. 
ISSN: 1815-9923. DOI: 10.3923/ajb.2011.98.103. Available from: 
http://scialert.net/qredirect.php?doi=ajb.2011.98.103&linkid=pdf 
http://www.scialert.net/fulltext/?doi=ajb.2011.98.103&org=10 
http://scialert.net/abstract/?doi=ajb.2011.98.103

62. Chikezie, P.C. (2011). Oxidative stress indicators of human sickle erythrocytes incubated in 
aqueous extracts of three medicinal plants. Asian Journal of Biochemistry. 6(5), 373-383. ISSN: 
1815-9923. DOI: 10.3923/ajb.2011.373.383. Available from: 
http://scialert.net/qredirect.php?doi=ajb.2011.373.383&linkid=pdf 
http://scialert.net/fulltext/?doi=ajb.2011.373.383&org=10 
http://www.scialert.net/abstract/?doi=ajb.2011.373.383

 63. Chikezie, P.C. and Uwakwe, A.A. (2011). Membrane lipid peroxidation of HbAA erythrocyte of 
non-malarious participants administered with quinine. Free Radicals and Antioxidants. 1(2), 20
24. ISSN: 2231-2536. DOI: 10.5530/ax.2011.2.5. Available from: 
http://dx.doi.org/10.5530/ax.2011.2.5  
http://www.sciencedirect.com/science/article/pii/S2231253611120056 
http://www.sciencedirect.com/science?_ob=ArticleListURL&_method=l.

64. Chikezie, P.C. (2011). Comparative In vitro osmotic stability of three human erythrocyte         
genotypes (HbAA, HbAS and HbSS) in the presence of quinine and chloroquine phosphate. 
Asian Journal of Biochemistry. 6(1), 55-64. ISSN: 1815-9923. DOI:10.3923/ajb.2011.55.64. 
Available from: 
http://scialert.net/qredirect.php?doi=ajb.2011.55.64&linkid=pdf  
http://scialert.net/fulltext/?doi=ajb.2011.55.64&org=10 
http://scialert.net/abstract/?doi=ajb.2011.55.64 
 http://scialert.net/archivedetails.php?issn=1815-9923&issueno=27

65. Chikezie, P.C. (2011). Sodium metabisulphite induced polymerization of sickle cell haemoglobin 
(HbS) incubated in extracts of three medicinal plants (Anacardium occidentale, Psidium guajava 
and Terminalia catappa). Pharmacognosy Magazine. 7(26), 126-132. ISSN: 0973-1296. DOI: 
10.4103/0973-1296.80670. Available from:  
http://www.ncbi.nlm.nih.gov/pubmed/21716622 
http://www.ncbi.nlm.nih.gov/m/pubmed/21716622/ 
http://www.phcog.com/text.asp?2011/7/26/126/80670 
http://www.phcog.com/article.asp?issn=0973-1296;year=2011;volume=.

66. Chikezie, P.C. and Uwakwe, A.A.  (2011). Membrane stability of sickle erythrocytes incubated in extracts of three medicinal plants: Anacardium occidentale, Psidium guajava and Terminalia 
catappa. Pharmacognosy Magazine. 7(26), 121-125. ISSN: 0973-1296. DOI:10.4103/0973
1296.80669. Available from: 
http://www.ncbi.nlm.nih.gov/pubmed/21716621 
http://www.ncbi.nlm.nih.gov/pmc/articles/pmc/3113350/ 
http://www.phcog.com/text.asp?2011/7/26/121/80669 
http://www.phcog.com/article.asp?issn=0973-1296;year=2011;volume=. 

67. Njoku, V.O., Chikezie, P.C. and Kaoje, A.M. (2011). Kinetic studies of alkaline phosphatase 
extracted from rabbit (Lepus townsendii) liver. African Journal of Biotechnology. 10(16), 3157
3162. ISSN: 1684-5315. DOI: 10.5897/AJB10.1421. Available from: 
http://www.academicjournals.org/AJB 
http://www.academicjournals.org/article/article1380789375_Njoku%20et%20al.pdf 68. Chikezie, P.C. (2011). Glutathione S–transferase activity of human erythrocytes incubated in 
aqueous solution of five antimalarial drugs. Free Radicals and Antioxidants. 1(2), 25-29. ISSN: 
2231-2536. DOI: 10.5530/ax.2011.2.6. Available from:  
http://www.sciencedirect.com/science/article/pii/S2231253611120068 
http://www.sciencedirect.com/science?_ob=ArticleListURL&_method=l... 
http://www.phcogfirst.com/article/727

69. Chikezie, P.C., Uwakwe, A.A. and Monago, C.C. (2010). Comparative osmotic fragility of three   
erythrocyte genotypes (HbAA, HbAS and HbSS) of male subjects/volunteers administered with  
five antimalarial drugs. African Journal of Biochemistry Research. 4(3), 57-64. ISSN: 1996-0778. 
Available from: 
http://hwww.academicjournals.org/journal/AJBR/article-abstract/AB649E611104 
http://www.academicjournals.org/article/article1380102613_Chikezie%20et%20al.pdf

70. Chikezie, P.C., Chikezie, C.M. and Amaragbulem, P.I. (2010). Effect of antimalarial drugs on 
polymerization of sickle cell hemoglobin (HbS). Turkish Journal of Biochemistry. 35(1), 41–44. 
ISSN: 1303–829X (electronic) 0250–4685. Available from: 
http://www.turkjbiochem.com/2010/041-044.pdf 
http://www.TurkJBiochem.com

71. Chikezie, P.C. (2009). Comparative methaemoglobin concentrations of three erythrocyte    
genotypes (HbAA, HbAS and HbSS) of male participants administered with five antimalarial 
drugs. African Journal of Biochemistry Research. 3(6), 266-271. ISSN: 1996-0778.  Available 
from:  
http://ms.academicjournals.org/journal/AJBR/article-abstract/662A21211129 
http://www.academicjournals.org/article/article1380102613_Chikezie%20et%20al.pdf

72. Chikezie, P.C., Monago, C.C. and Uwakwe, A.A. (2009). Studies of methaemoglobin contents of three human erythrocyte genotypes (HbAA, HbAS and HbSS) in the presence of five anti- 
malarial drugs. Iranian Journal of Blood and Cancer (IJBC). 1(4), 151-157. ISSN: 2008-4595. 
Available from:  
http://ijbc.ir/browse.php?mag_id=1&slc_lang=en&sid=1  

73. Chikezie, P.C., Uwakwe, A.A. and Monago, C.C. (2009). Glutathione S-transferase activity of 
three erythrocyte genotypes (HbAA, HbAS and HbSS) of male subjects/volunteers administered 
with Fansidar and Quinine. African Journal of Biochemistry Research. 3(5), 210-214. ISSN: 1996
0778. Available from: 
http://www.academicjournals.org/journal/AJBR/article-abstract/0250B9B11051 
http://www.academicjournals.org/article/article1380101458_Chikezie%20et%20al.pdf

74. Chikezie, P.C., Chikezie, C.M., Uwakwe, A.A. and Monago, C.C. (2009). Comparative study of    
glutathione S-transferase activity of three human erythrocyte genotypes infected with Plasmodium falciparum. Journal of Applied Science and Environmental Management 13(3), 13
18. ISSN: 1119-8362. Available from: 
www.bioline.org.br/ja  
http://www.bioline.org.br/request?ja09032

75. Chikezie, P.C., Chikezie, C.M., Uwakwe, A.A. and Monago, C.C. (2009). Investigation on 
methaemoglobin concentration of three human erythrocyte genotypes infected with 
Plasmodium falciparum. Journal of Applied Science and Environmental Management. 13(3), 5-8. 
ISSN: 1119-8362. Available from: 
www.bioline.org.br/ja  
http://www.bioline.org.br/request?ja09030

76. Chikezie, P.C., Uwakwe, A.A. and Monago, C.C. (2009). Studies of the human HbAA erythrocytes 
osmotic fragility index of non malarious blood in the presence of five antimalarial drugs. 
Journal of Cell and Animal Biology. 3(3), 039-043. ISSN: 1996-0867. Available from: 
http://www.academicjournals.org/journal/JCAB/article-abstract/B64CB3D12674 
http://www.academicjournals.org/article/article1380191023_Chikezie%20et%20al.pdf

77. Chikezie, P.C., Uwakwe, A.A. and Monago, C.C. (2009). Erythrocyte glutathione S-transferase 
the activity of non-malarious male human volunteers administered with five antimalarial drugs. 
Cameroon Journal of Experimental Biology.  5(2), 112-116. ISSN: 1816-0573. Available from:  
http://dx.doi.org/10.4314%2Fjophas.v6i3.48543 
http://www.ajol.info/browse-journals.php 
 
78. Chikezie, P.C., Chikezie, C.M. and Nwanegwo, C.O. (2008). Osmotic fragility index of chicken 
(Gallus gallus) and human HbAA erythrocytes. International Science Research Journal. 1(1), 1-4. 
ISSN: 2006–1730. Available from: 
http://www.isrjournals.com 79. Chikezie, P.C., Keke, I.R., Uwakwe, A.A. and Monago, C.C. (2008). In vitro studies of human 
erythrocyte glutathione S-transferase activity in the presence of five antimalarial drugs. 
International Science Research Journal. 1(2), 103-106. ISSN: 2006–1730. Available from: 
http://www.academicpublications.org/archive/volume1%282%29/103106%20Paul%20et%20al
.pdf 

80. Chikezie, C.M. and Chikezie, P.C. (2008). Comparative osmotic fragility of three human   
erythrocyte genotypes infected with Plasmodium falciparum. Journal of Biological and      
Environmental Sciences. 2, 58-62. ISSN: 2006-4993. Available from: 
http://www.jobescience.com. 

 81. Chikezie, P.C. (2007). Effect of ethanolic extracts of Garcina kola, Cola nitida and Cola 
acuminata on in vitro haemoglobin S polymerization. International Journal of Tropical 
Agricultural and Food Systems. 1(3), 220-224. ISSN: 0794-4700. Available from: 
http://dx.doi.org/10.4314%2Fijotafs.v1i3.40917 82. Chikezie, P.C. (2007). The effect pyrimethamine and sulphadoxine mixture on plasma haemoglobin/methaemoglobin ratio of HbAA erythrocytes. International Journal of Natural and 
Applied Sciences. 3(1), 116-121. ISSN: 0794-4713. Available from: 
http://www.ajol.info/index.php/ijonas/article/view/36153

83. Chikezie, P.C. (2007). Effect of cinnamic acid on polyphenol oxidase activity of Dioscorea 
rotundata. Global Journal of Pure and Applied Science. 13(3), 387-389. ISSN: 1118-0579. 
Available from: 
http://www.ajol.org  
http://www.ajol.info/index.php/gjpas/article/view/16724

84. Chikezie, P.C. (2007). Osmotic fragility index of HbAA red blood cells in the presence of 
aqueous extracts of three medicinal plants (Aframomum melegueta, Garcina kola and 
Cymbopogon citracus). Global Journal of Pure and Applied Sciences. 13(4), 496-499. ISSN: 1118
0579.  Available from:  
http://dx.doi.org/10.4314%2Fgjpas.v13i4.16744

 85. Chikezie, P.C., Amadi, B.A. and Chikezie, C.M. (2007). Evaluation of two polyphenol oxidase 
kinetic parameters at three stages of Musa sapietum fruit maturation. International Journal of 
Agriculture and Food Systems. 1(1), 63-67. ISSN: 0794-4700. Available from: 
http://dx.doi.org/10.4314%2Fijotafs.v1i1.40888

86. Amadi, B.A., Chikezie, P.C. and Okeoma, H.C. (2006). Physicochemical characteristics of Nworie River and its effect on the liver function of rats. Journal of Nigerian Environmental Society (JNES). 
3(3), 173-177. Available from:  
http://www.bioline.org 

 87. Chikezie, P.C. (2006). Effect of phenacetin on NADH-methaemoglobin reductase of human 
erythrocytes. Global Journal of Pure and Applied Science. 12(3), 339-342. ISSN: 0794-4713. 
Available from: 
http://dx.doi.org/10.4314%2Fgjpas.v12i3.16615 88. Chikezie, P.C. (2006). Studies on the anti-sickling effect of Azadirachta indica and Veronica 
amygdalina on HbSS erythrocytes. International Journal of Natural and Applied Sciences. 2(1), 
24-28. ISSN: 0794-4713. Available from:  
http://dx.doi.org/10.4314%2Fijonas.v2i1.36041

89. Chikezie, P.C. and Akuwudike, A.R. (2006). Comparative in vitro effect of ethanolic extracts of 
Cola nitida and Cola acuminata on plasma levels of methaemoglobin of HbAA erythrocytes. 
Journal of Biological and Environmental Sciences. 1, 34-38. ISSN: 2006-4993. Available from: 
http://www.besjournal.50meg.com 
http://www.science.pub.net 90. Chikezie, P.C. (2006). Extraction and activity of polyphenol oxidase from kolanuts (Cola nitida 
and Cola acuminata) and cocoa (Theobroma cacao). Journal of Agriculture and Food Sciences. 
4(2), 115-124. ISSN: 0794-4700. Available from: 
http://web.mnstate.edu/marryand/BiochemIILab/polyphenol%20oxidase.pdf 
www.imsu-jafs.info

91. Chikezie, P.C. and Enemor, V.H.A. (2005). Effect of experimental quinine administration on 
plasma levels of haemoglobin and methaemoglobin in guinea pigs. International Journal of 
Natural and Applied Science. 1(2), 150-153. ISSN: 0794-4713. Available from: 
http://dx.doi.org/10.4314%2Fijonas.v1i2.36078

92. Enemor, V.H.A., Anosike, J.C., Nwoke, B.E.B. and Chikezie, P.C. (2005). Serum aminotransferases and bilirubin levels in malaria patients. International Journal of Natural and 
Applied Sciences. 1(2), 85-89. ISSN: 0794-4713. Available from:  
http://dx.doi.org/10.4314%2Fijonas.v1i2.36067

93. Chikezie, P.C. and Ibegbulem, C.O. (2004). Effect of quinine on osmotic fragility of HbAA red 
blood cells of guinea pigs. Journal of Innovation of Life Sciences. 8, 5-8. ISSN: 1117-5206.

94. Okogun, G.R.A., Chikezie, P.C., Nwosu, C.M., Anosike, J.C. and Amadi, A.N. (2004). Effect of 
three kola species, Garcina kola, Cola nitida and Cola acuminata on sickling of human 
erythrocytes. Journal of Applied and Basic Sciences. 2(1 and 2), 47-53.