International journal of Nano Scientific Networks and Nanotechnology (IJNN) is a multidisciplinary, peer reviewed journal which includes all the major fields in nanotechnology and Nano science. Nanoscience and nanotechnology brought up an unprecedented excitement in the scientific and engineering communities, especially the last decade. It is the engineering of functional systems at the molecular scale. This covers both current work and concepts that are more advanced.  International journal of Nano Scientific Networks and Nanotechnology   publishes original research papers during a broad area of nanoscience & engineering. IJNN provides an ideal forum for presenting original reports of theoretical and experimental nanoscience and nanotechnology research. Nanotechnology is a gathering of rising innovations in which the structure of matter is controlled at the nanometer scale, the size of little quantities of molecules, to create novel materials and gadgets that have valuable and one of kind properties. IJNN is naturally multidisciplinary, and welcomes submissions across biological, physical, engineering, and computer sciences. Contributions from both academia and industry are equally encouraged. IJNN also publishes innovative techniques and instrumentation for the fabrication, characterization and testing of nano-enabled devices and technologies, as well as advanced modelling and simulation methods.


committee

Members

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WANG Zheng Ming

scientist

Dr WANG is a scientist working at Veterinary Public Health Centre, Singapore. He received his medical training (1981) in Shanghai, China; then Master’s degree (1992) and PhD degree (1998) in Physiology Department and Pathology Department, Medical School, Melbourne University respectively. During his PhD training period, he focused the research in mammalian development biology, dissecting the role of the mammalian Son of sevenless 1 (Sosl) protein in growth factor signaling in vivo by generating mice and cell lines that lacked the Sosl protein. Homozygous null embryos were smaller than normal, died mid-gestation with cardiovascular and yolk sac defects, and their fibroblasts showed reduced mitogen-activated protein kinase activation in response to epidermal growth factor (EGF). An intercross of mice mutant for Sosl and the EGF receptor (EGFR) demonstrated that a heterozygous mutation in Sosl dominantly enhanced the phenotype of a weak allele of the EGFR allele (wa-2). These animals had distinctive eye defects that closely resembled those seen in mice that were null for the EGFR or its ligand, TGFa. His findings provide the first demonstration of a functional requirement for Sosl in growth factor signaling in vivo. The results also show that the genetic test of enhancement of weak receptor allele by heterozygous mutation in one component represents a powerful tool for analyzing the ras pathway in mammals.

From 1998 to 2005, Dr WANG moved to Singapore, worked in Institute of Molecular & Cell Biology (IMCB) for 4 years, then in Medical School, National University of Singapore for 4 years respectively. During these times, Dr WANG’s research focus were on stem cell biology.

Dr WANG has joined Veterinary Public Health Centre, Singapore since 2005 where he is currently held a position of scientist. Dr WANG’s research field and interests are in emergent risk and risk assessment in agriculture and food sector. His works have covered from Genetically Modified Organism, to nanotechnology in agriculture and food production.

 

Current Research

  • Toxicity (cytotoxicity and genotoxicity) Analysis of nano particles using in vitro system
  • Characterization of nano particles used in agriculture and food production
  • Detection and quantification of nano particles in complex food matrices
  • Nano-materials lifecycle analysis (LCA)

Interested topics

  • Interaction between nano particles and food matrices
  • Interaction between nano particles and cellular component, cellular uptake of nano materials, cellular localization of the nanomaterials, and excretion mechanism of the nanomaterials in relation with nano toxicity
  • Characterization of the nanoparticle coronal feature and its effect
  • In vivo distribution of the different nano materials in different organs / system after exposure

International collaborations

  1. Philip DEMOKRITOU, Prof. Director, Centre for Nanotechnology & Nanotoxicology, Harvard T. Chan School of Public Health, Harvard University, USA

(nano materials characterization and toxicological analysis)

  1. Ralf GREINER, Prof. Dr. Head, Department of Food Technology and Bioprocess Engineering, Max Rubner-Institute, Federal Research Institute of Nutrition and Food, Karlsruhe, Germany

(nano materials characterization and toxicological analysis)

  1. HaiYan XU, Prof. Institute of Basuc Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China

(biomedical engineering, nanomaterials characterization, nanomaterials synthesis, etc..)

  1. Kee Woei NG, Prof. School of Materials Science and Engineering, Nanyang

Technological University, Singapore

((nanomaterials characterization, nanomaterials synthesis, biomedical engineering, nanotoxicological analysis, etc..)

Editorships

I have been regularly invited reviewing submitted MSs for «Journal of Agricultural and Food Chemistry» and «Food Control»

I am also a member of Singapore national expert panel in ISO TC 229 nanotechnology, the Singapore TC229 is a national body (under Singapore chemical council) oversees the safe and sustainable development of the nanotechnology in Singapore.

Conference Organization

  • Coordinator of the ASEAN Genetically Modified Food Testing Network since 2013 (to date), coordinate and organizing annual network meeting

1.Saji George, Shirley S. Ho, Esther S. P. Wong, Timothy Thatt Yang Tan, Navin Kumar Verma, Robert J. Aitken, Michael Riediker, Christopher Cummings, Liya Yu, Zheng Ming Wang, Daniele Zink, Zhihan Ng, Say Chye Joachim Loo, and Kee Woei Ng (2015)The multi-facets of sustainable nanotechnology – Lessons from a nanosafety symposium. Nanotoxicology, 2015; 9(3): 404–406

2. Ridhwan Yusoff, Luong T. H. Nguyen, Paul Chiew, Zheng Ming Wang& Kee Woei Ng (2018) Comparative differences in the behavior of TiO2 and SiO2 food additives in food ingredient solutions. J Nanopart Res 20:76

3. Yang L, Guo J, Pan A, Zhang H, Zhang K, Wang Z, Zhang D. (2007) Event-Specific Quantitative Detection of Nine Genetically Modified Maizes Using One Novel Standard Reference Molecule. J Agric Food Chem. 55(1):15-24.

4. Wang DZ,Skinner S, Elliot R, Escobar L, Salto-Tellez M, Garkavenko O, Khoo A, Lee KO, Calne R, Isaac JR. (2005) Xenotransplantation of neonatal porcine islets and Sertoli cells into nonimmunosuppressed streptozotocin-induced diabetic rats. Transplant Proc. 37(1):470-1.

5. Isaac JR, Skinner S, Elliot R, Salto-Tellez M, Garkavenko O, Khoo A, Lee KO, Calne R, Wang DZ. (2005) Transplantation of neonatal porcine islets and sertoli cells into nonimmunosuppressed nonhuman primates. Transplant Proc. 37(1):487-8.

6. Heng BC, Cao T, Haider HK, WangDZM, Sim EK, Ng SC (2004) An overview and synopsis of techniques for directing stem cell differentiation in vitro. Cell Tissue Res 315:291–303.

7. Ponniah S, Wang DZM, Lim KL, and Pallen CJ (1999) Targeted disruption of the tyrosine phosphatase PTPalpha leads to constitutive downregulation of the kinases Src and Fyn. Current Biology 9(10):535-8.

8.Wang DZM, Hammond VE, Abud HE, Bertoncello I, McAvoy JW & Bowtell DDL. (1997) Mutation in Sos1 dominantly enhances a weak allele of the EGFR, demonstrating a requirement for Sos1 in EGFR signalling and development. Gene and Development 11(3): 309- 320.