International journal of Nano Scientific Networks and Nanotechnology (IJNN) is a multidisciplinary, peer reviewed journal which includes all the major fields in nanotechnology and Nano science. Nanoscience and nanotechnology brought up an unprecedented excitement in the scientific and engineering communities, especially the last decade. It is the engineering of functional systems at the molecular scale. This covers both current work and concepts that are more advanced.  International journal of Nano Scientific Networks and Nanotechnology   publishes original research papers during a broad area of nanoscience & engineering. IJNN provides an ideal forum for presenting original reports of theoretical and experimental nanoscience and nanotechnology research. Nanotechnology is a gathering of rising innovations in which the structure of matter is controlled at the nanometer scale, the size of little quantities of molecules, to create novel materials and gadgets that have valuable and one of kind properties. IJNN is naturally multidisciplinary, and welcomes submissions across biological, physical, engineering, and computer sciences. Contributions from both academia and industry are equally encouraged. IJNN also publishes innovative techniques and instrumentation for the fabrication, characterization and testing of nano-enabled devices and technologies, as well as advanced modelling and simulation methods.




Kaiyong Cai


Dr. Kaiyong Cai is a Professor in biomaterials and nanomedicine. He received his Ph.D. degree in Biomedical Engineering from Tianjin University in 2002. He is a distinguished Professor of Cheung Kong Scholars. He was awarded China Youth Science & Technology Award in 2011. His research interests include biointerfeces of biomaterials and controlled drug delivery system. He has published more than 150 articles in peer-reviewed international journals with over 3800 citations. He is editorial board member of journals such as Frontiers of Materials Science, World Journal of Stem Cells, AIMS Materials Science. He is also an ad-hoc reviewer for more than 60 international journals such as Chem Soc Rev, J Am Chem Soc, Adv Mater, Angew Chem Int Edit, Nano Lett, Biomaterials, ACS Nano, Small et al.

  1. Jun Zhou, Menghuan Li, Zhong Luo*, Qiufang Chen, Hexu Cao, Runlan Huo, Chencheng Xue, Linawati Sutrisno, Lan Hao, Yang Cao, Haitao Ran, Lu Lu, Ke Li, Kaiyong Cai*. Engineering of a Nanosized Biocatalyst for Combined Tumor Starvation and Low-temperature Photothermal Therapy. ACS Nano 2018, DOI: 10.1021/acsnano.8b00309.
  2. Liangliang Dai, Ke Li, Menghuan Li, Xiaojing Zhao, Zhong Luo, Lu Lu, Yanfeng Luo, Kaiyong Cai*. Size/Charge Changeable Acidity-Responsive Micelleplex for Photodynamic-Improved PD-L1 Immunotherapy with Enhanced Tumor Penetration. Adv Func Mater 2018, 28,1707249.
  3. Jinghua Li, Xiangyang Zu, Gaofeng Liang, KeKe Zhang, Yuliang Liu*, Ke Li, Zhong Luo, Kaiyong Cai*. Octopod PtCu Nanoframe as Multifunctional Theranostic Nanoplatform for Dual-Modal Imaging-Guided Synergistic Photothermal Radiotherapy. Theranostics 2018, 8(4), 1042-1058.
  4. Junjie Liu, Huining Liang, Menghuan Li, Zhong Luo, Jixi Zhang, Xingming Guo, Kaiyong Cai*. Tumor acidity activated multifunctionalnanoplatformfor NIR-mediated multiple enhanced photodynamic and photothermal tumor therapy. Biomaterials 2018, 157, 107-124.
  5. Junjie Liu, Menghuan Li, Zhong Luo, Liangliang Dai, Xingming Guo, Kaiyong Cai*. Design of nanocarriers based on complex biological barriers in vivo for tumor therapy. Nano Today 2017, 15, 56-90.
  6. Menghuan Li, Zhong Luo*, Zhining Xia, Xinkun Shen, Kaiyong Cai*. Time-sequenced drug delivery approaches towards effective chemotherapeutic treatment of glioma. Materials Horizons 2017, 4, 977 - 996.
  7. Liangliang Dai, Ruisi Cai, Menghuan Li, Zhong Luo, Yonglin Yu, Weizhen Chen, Xinkun Shen, Yuxia Pei, Xiaojing Zhao, Kaiyong Cai*. Dual-Targeted Cascade-Responsive Prodrug Micelle System for Tumor Therapy in Vivo. Chem Mater 2017, 29, 6976-6992.
  8. Yuxin Xing, Jixi Zhang*, Feng Chen, Junjie Liu and Kaiyong Cai*. Mesoporous polydopamine nanoparticles with co-delivery function for overcoming multidrug resistance via synergistic chemo-photothermal therapy. Nanoscale, 2017, 9, 8781–8790.
  9. Jinghua Li*, Fengshou Zhang, Zhigang Hu, Weidong Song, Guangda Li, Gaofeng Liang, Jun Zhou, Ke Li, Yang Cao, Zhong Luo and Kaiyong Cai*. Drug “Pent-Up” in Hollow Magnetic Prussian Blue Nanoparticles for NIR-Induced Chemo-Photothermal Tumor Therapy with Trimodal Imaging. Advanced Healthcare Materials 2017, 6, 1700005.
  10. Liangliang Dai, Yonglin Yu, Zhong Luo, Menghuan Li, Weizhen Chen, Xinkun Shen, Feng Chen, Qiang Sun, Qingfeng Zhang, Hao Gu, Kaiyong Cai*. Photosensitizer enhanced disassembly of amphiphilic micelle for ROS-response targeted tumor therapy in vivo. Biomaterials 2016, 104, 1-17.
  11. Junjie Liu, Zhong Luo, Jixi Zhang, Tiantian Luo, Jun Zhou, Xiaojing Zhao, Kaiyong Cai*. Hollow mesoporous silica nanoparticles facilitated drug delivery via cascade pH stimuli in tumor microenvironment for tumor therapy. Biomaterials 2016, 83, 51-65.
  12. Liangliang Dai, Qingfeng Zhang, Jinghua Li, Xinkun Shen, Caiyun Mu, and Kaiyong Cai*. Dendrimer-Like Mesoporous Silica Nanoparticles as pH-responsive Nanocontainers for Targeted Drug Delivery and Bioimaging. ACS Applied Materials & Interfaces 2015, 7 (13), 7357-7372.
  13. Junjie Liu, Beilu Zhang, Zhong Luo, Xingwei Ding, Jinghua Li, Liangliang Dai, Jun Zhou, Xiaojing Zhao, Jingya Ye and Kaiyong Cai*. Enzyme responsive mesoporous silica nanoparticles for targeted tumor therapy in vitro and in vivo. Nanoscale2015, 7, 3614-3626.
  14. Jinghua Li, Yan Hu, Yanhua Hou, Xinkun Shen, Gaoqiang Xu, Liangliang Dai, Jun Zhou, Yun Liu and Kaiyong Cai*. Phase-change material filled hollow magnetic nanoparticles for cancer therapy and dual modal bioimaging. Nanoscale 2015, 7, 9004-9012.
  15. Beilu Zhang, Zhong Luo, Junjie Liu, Xingwei Ding, Jinghua Li and Kaiyong Cai*. Cytochrome c end-capped mesoporous silica nanoparticles as redox-responsive drug delivery vehicles for liver tumor-targeted triplex therapy in vitro and in vivo. J. Controll Rel. 2014, 192: 192-201.
  16. Xingwei Ding, Yun Liu, Jinghua Li, Zhong Luo, Yanhua Hou, Yan Hu, Beilu Zhang, Junjie Liu, Jun Zhou and Kaiyong Cai*. Hydrazone-Bearing PMMA-Functionalized Magnetic Nanocubes as pH-Responsive Drug Carriers for Remotely Targeted Cancer Therapy in Vitro and in Vivo. ACS Applied Materials & Interfaces, 2014, 6: 7395-7407.
  17. Zhong Luo, Xingwei Ding, Yan Hu, Shaoquan Wu, Yang Xiang, Yongfei Zeng, Hong Yan, Hua-cheng Zhang, Liangliang Zhu, Junjie Liu, Jinghua Li, Kaiyong Cai,* and Yanli Zhao*. Engineering a Hollow Nanocontainer Platform with Multifunctional Molecular Machines for Tumor-Targeted Therapy in Vitro and in Vivo. ACS Nano, 2013; 7(11): 10271-10284.
  18. Zhong Luo, Kaiyong Cai*, Yan Hu, Jinghua Li, Xingwei Ding, Beilu Zhang, Dawei Xu, Weihu Yang, Peng Liu. Redox-responsive molecular nanoreservoirs for controlled intracellular anticancer drug delivery based on magnetic nanoparticles.  Advanced Materials 2012, 24, 431-435.
  19. Yuran Huang, Sha He, Weipeng Cao, Kaiyong Cai*, Xingjie Liang*. Biomedical nanomaterials for imaging-guided cancer therapy. Nanoscale 2012, 4, 6135-6149.
  20. Xingwei Ding, Kaiyong Cai*, Zhong Luo, Jinghua Li, Yan Hu and Xinkun Shen. Biocompatible magnetic liposomes for temperature trigged drug delivery. Nanoscale, 2012, 4:6289-6292.
  21. Zhong Luo, Kaiyong Cai*, Yan Hu, Beilu Zhang, Dawei Xu. Cell-specific intracellular anticancer drug delivery from mesoporous silica nanoparticles with pH-sensitivity. Adv Healthcare Mater. 2012; 1:321-325.
  22. Zhong Luo, Kaiyong Cai*, Yan Hu, Li Zhao, Peng Liu, Lin Duan, Weihu Yang. Mesoporous silica nanoparticles end-capped with collagen: redox-responsive nanoreservoirs for targeted drug delivery. Angew Chem Int Ed. 2011;50(3) :640-643.
  23. Kaiyong Cai*, Yanhua Hou, Yan Hu, Li Zhao, Zhong Luo, Yisong Shi, Min Lai, Weihu Yang, Peng Liu. Correlation of the cytotoxicity of TiO2 nanoparticles with different particle sizes on a sub-200-nm scale. Small, 2011; 7(21):3026-3031.
  24. Kaiyong Cai*, Jinghua Li, Zhong Luo, Yan Hu, Yanhua Hou, Xingwei Ding. beta-Cyclodextrin conjugated magnetic nanoparticles for diazepam removal from blood. Chem Commun. 2011, 47 (27), 7719 – 7721.
  25. Yan Hu, Kaiyong Cai*, Zhong Luo, Klaus D. Jandt. Layer-By-Layer Assembly of beta-estradiol loaded mesoporous silica nanoparticles on titanium substrates and its implication for bone homeostasis. Advanced Materials. 2010; 22(37):4146-4150.
  26. Kaiyong Cai*, Zhong Luo, Yan Hu, Xiuyong Chen, Li Yang, Linhong Deng. Magnetically triggered reversible controlled drug delivery from microfabricated polymeric multireservoir devices. Advanced Materials. 2009; 21(40): 4045-4049.