International Journal of Immunology is a peer-reviewed open access journal that publishes original research articles as well as review articles in all areas of immunology. Immunology is a diverse and growing discipline that can be defined as the study of the tissues, cells and molecules involved in host defense mechanisms. Immunologists attempt to understand how the immune system develops, how the body defends itself against disease, and what happens when it all goes wrong. Priority is given to work that provides fundamental insight into the workings of the immune system. Areas covered include, but are not limited to, innate immunity and inflammation; development; immune receptors, signaling and apoptosis; antigen presentation; gene regulation and recombination; cellular and systemic immunity; vaccines; immune tolerance; autoimmunity and tumor immunology, microbial immunopathology; and transplantation.

The great advances in immunology in recent years make this field one of the most dynamic and rapidly growing in biological sciences. This remarkable growth is stimulated by the influx of investigators from other disciplines such as biochemistry, genetics, molecular biology, microbiology, virology and various medical disciplines. These disciplines are so well interlinked with immunology that no immunological challenge can now be properly addressed without sophisticated applications of expertise of combinations of these disciplines. As a consequence, immunology has become a vast and rich field encompassing discoveries and outlooks that range from the highly clinical to the highly molecular. Although such perspectives may appear diverse, they are, in fact, extremely interdependent. The journal seeks to present a balanced overview of contemporary immunology and melds together different aspects of molecular immunology, immunobiology and clinical immunology.

Immunology is the branch of biomedical science that deals with the response of an organism to antigenic challenge and its recognition of what is self and what is not. It deals with the defense mechanisms including all physical, chemical and biological properties of the organism that help it to combat its susceptibility to foreign organisms, material, etc

Immunology has its origins in the study of how the body protects itself against infectious diseases caused by microorganisms, such as bacteria, viruses, protozoa, and fungi, and also parasitic organisms, such as helminth worms. Research / review articles deals with, among other things, the physiological functioning of the immune system in states of both health and disease; malfunctions of the immune system in immunological disorders (autoimmune diseases, hypersensitivities, immune deficiency, transplant rejection); the physical, chemical and physiological characteristics of the components of the immune system in vitro, in situ, and in vivo are of prime interest.


committee

Members

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Vishal K Khatri

Post-Doctoral Research Associate

Dr. Vishal Khatri was born in India. He has received his both bachelor’s and Master’s Degree in Biochemistry from India. He earned his Ph.D. Degree in Medical Biochemistry from MUHS, Nasik, India while working at Dr. Reddy’s lab at Mahatma Gandhi Institute of Medical Sciences, Sevagram, India. During his doctoral research he has primarily worked towards identification of filarial parasite derived recombinant proteins of bio-therapeutic potential against experimental ulcerative colitis in mice model. He has also worked towards development of vaccine candidates for lymphatic filariasis. A neglected tropical disorder currently infecting more than 120 million people worldwide, about 40 million are left disfigured or incapacitated by the disease and 856 million people in 52 countries are at risk of developing the disorder. He has also carried out several fields works and collected night blood samples from filarial endemic regions of India. Actively contributed towards development of potential drug and a rapid flow diagnostic test for LF. He later joined as a Post-doctoral Research Associate at University of Illinois College of Medicine at Rockford at Dr. Ramaswamy’s lab. Recently his lab has successfully completed a protection study for LF using a tetra-valent vaccine candidate in primates.

His present interest lies towards translating a filarial parasite derived immunomodulatory protein cystatin in clinics for the treatment of colitis and other immune-dysregulatory disorders. The studies conducted in experimental mice models showed exciting results with no observed side-effects.

During his journey as a young researcher, he has mentored several graduate and Ph.D. students, contributed about 16 peer-reviewed articles in high impact factor journals and has also presented his work in several international conferences.

 

 

 

 

       Current Research

  • Filarial vaccine, drugs and diagnostics development
  • Helminth derived immune-therapeutics for autoimmune, allergic and inflammatory disorders
  • Development of vaccine for heart-worm disease

    Interested topics

     
  • Site-specific filarial derived bio-therapeutics in colitis
  • Nano-particle mediated drug delivery systems for type-1 diabetes
  • Helminth immune-response and epi-genetic modifications
  • 2008 – “Deepa Biswas Memorial Best Student Award (2007-08)” at Dr. Ambedkar College, Nagpur.
  • 2011 - “P.S. Murthy best paper award” for the paper entitled “Brugia malayi cysteine proteinase inhibitor induces protection against filarial infection” at ACBICON-2011 held at Gwalior during Dec 4-6, 2011.
  • 2012 - Indian Immunology Society (IIS) Bursary Award for the year 2012.
  • 2012 - “Best poster award” for the poster entitled “Evaluation of therapeutic role of filarial antigens on the development of type 1 diabetes” presented at 39th Annual conference of Association of Clinical Biochemists of India (ACBICON 2012) held at Ranchi during 11-13th Dec 2012.
  • 2013 - Indian Immunology Society (IIS) Bursary Award for the year 2013
  • 2015 - Paper entitled “Brugia malayi cystatin as a novel bio-therapeutic agent to attenuate inflammatory and auto-immune conditions” shortlisted for “Dr. GP Talwar Young Scientist Award – 2015” at Immunocon 2015 Conference held at Patna.
  • 2017 - University of Illinois College of Medicine Rockford recognition of scholarly contributions, Jan-Dec 2017.

Membership

  • Life member of Indian Immunology Society
  • Member of Federation of Clinical Immunology Societies (FOCIS)

Editorships

  • About 16 peer-review publications
  • Reviewer in PlosOne, Parasitol Res, Asian Pac J Trop Biomed & Royal Soc. Open Sci journals
  • Mentored four graduate students
  • Reviewer for “Research Day abstracts” and guest speaker at UIC College of Medicine Rockford
  • Total Citations: 43, h-index: 4, i10-index: 1

Conference Organization

  • Resource person in the Department of Biotechnology (DBT) sponsored National level Training
    course on “Molecular techniques as applied for infectious disease research” organized at Dept. of Biochemistry and JBTDRC, MGIMS, Sewagram. (2015, 2014, 2013 & 2011).
  • Over twenty-four Conference presentations