International Journal of Immunology is a peer-reviewed open access journal that publishes original research articles as well as review articles in all areas of immunology. Immunology is a diverse and growing discipline that can be defined as the study of the tissues, cells and molecules involved in host defense mechanisms. Immunologists attempt to understand how the immune system develops, how the body defends itself against disease, and what happens when it all goes wrong. Priority is given to work that provides fundamental insight into the workings of the immune system. Areas covered include, but are not limited to, innate immunity and inflammation; development; immune receptors, signaling and apoptosis; antigen presentation; gene regulation and recombination; cellular and systemic immunity; vaccines; immune tolerance; autoimmunity and tumor immunology, microbial immunopathology; and transplantation.

The great advances in immunology in recent years make this field one of the most dynamic and rapidly growing in biological sciences. This remarkable growth is stimulated by the influx of investigators from other disciplines such as biochemistry, genetics, molecular biology, microbiology, virology and various medical disciplines. These disciplines are so well interlinked with immunology that no immunological challenge can now be properly addressed without sophisticated applications of expertise of combinations of these disciplines. As a consequence, immunology has become a vast and rich field encompassing discoveries and outlooks that range from the highly clinical to the highly molecular. Although such perspectives may appear diverse, they are, in fact, extremely interdependent. The journal seeks to present a balanced overview of contemporary immunology and melds together different aspects of molecular immunology, immunobiology and clinical immunology.

Immunology is the branch of biomedical science that deals with the response of an organism to antigenic challenge and its recognition of what is self and what is not. It deals with the defense mechanisms including all physical, chemical and biological properties of the organism that help it to combat its susceptibility to foreign organisms, material, etc

Immunology has its origins in the study of how the body protects itself against infectious diseases caused by microorganisms, such as bacteria, viruses, protozoa, and fungi, and also parasitic organisms, such as helminth worms. Research / review articles deals with, among other things, the physiological functioning of the immune system in states of both health and disease; malfunctions of the immune system in immunological disorders (autoimmune diseases, hypersensitivities, immune deficiency, transplant rejection); the physical, chemical and physiological characteristics of the components of the immune system in vitro, in situ, and in vivo are of prime interest.




Alejandro Vallejo

Principal Investigator

After obtaining my Academic Degree in Molecular Biology and Biochemistry at the Autonoma University, Madrid, Spain, I initiated my Ph.D. Student Program at the Carlos III Health Institute, Majadahonda. My initial field of research was the study of HTLV infections among HIV-1 infected patients. I also initiated some epidemiologic research on HIV infections, including HIV-1 group O and HIV-2.

I moved to the Laboratory of Molecular Virology, CBER, Food and Drug Administration, Bethesda, MD, USA, as aPost DoctoralFellow (1995-2000) and developed my work on molecular epidemiology of HTLV and HIV, and viral tropism. Then I joined the Immunovirology Laboratory at the VirgendelRocío University Hospital, Seville, Spain, as an independent researcher (2000-2008). I focused my research on immune recovery of HIV-1-infected patients. Then I moved to Ramon y Cajal University Hospital in Madrid to follow my research on HIV-1 immunopathology and continuing the research on HTLV-1/2 infections (2008- ) running the Laboratory of Molecular Virology within the Infectious Diseases Department..

I also coordinate the subject Methods in Virology included in the Master of Virology at the Complutense University (UCM) in Madrid. I am also member of the Editorial Board of Scientific Journals such as Medicine, Current Immunology Reviews, and The Open Immunology Journal. I collaborate as a reviewer for human resources and projects in Spanish National Evaluation Agencies (ANEP, FIS).

Current Research

  • HIV pathology
  • HTLV immunology

Interested topics

  • Therapy
  • Immune response
  • Co-infections
  • 1989 - Fellow, Institute of Health Carlos III, Majadahonda, Madrid, Spain 
  • 1995 – Fellow, Food and Drug Administration, Bethesda, MD
  • 2000 – Outstanding response to a public health crisis using team work, regulatory science and public interaction. Center for Biologics Evaluation and Research´s Center Director´s Distinguished Service Award as a member of Gene Therapy Working Group – Testing. Food and Drug Administration. Department of Health and Human Services – USA
  • 2009 - Member, Research Committee, University Hospital Ramon y Cajal, Madrid, Spain (6 years)
  • 2010 – Member, Scientific Committee BioBank, University Hospital Ramon y Cajal, Madrid, Spain (5 years)

           International collaborations

  • Food and Drug Administration, Bethesda, MD

  • 1993 – Spanish Society of Infectious Diseases and Clinical Microbiology
  • 2003 – HIV National Network, Spain (16 years)
  • 2008 – Advisory Board, Current Immunology Reviews
  • 2008 – Advisory Board, The Open Immunology Journal
  • 2008 – Advisory Board, The Open Microbiology Journal
  • 2007 – International Scholar, The Nightingale Initiative for Global Health
  • 2012 – Spanish Society of Virology
  • 2013 – International RetrovirologyAssotiation
  • 2015 – Academic Editorial Board HIV/AIDS, Medicine (Wolters Kluwer)
  • 2017 – Editorial Board, Annal of Clinical Virology
  • 2017 – Editorial Board, Journal of Immunology Forecast
  • Over 90 peer-review publications
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