International Journal of Immunology is a peer-reviewed open access journal that publishes original research articles as well as review articles in all areas of immunology. Immunology is a diverse and growing discipline that can be defined as the study of the tissues, cells and molecules involved in host defense mechanisms. Immunologists attempt to understand how the immune system develops, how the body defends itself against disease, and what happens when it all goes wrong. Priority is given to work that provides fundamental insight into the workings of the immune system. Areas covered include, but are not limited to, innate immunity and inflammation; development; immune receptors, signaling and apoptosis; antigen presentation; gene regulation and recombination; cellular and systemic immunity; vaccines; immune tolerance; autoimmunity and tumor immunology, microbial immunopathology; and transplantation.

The great advances in immunology in recent years make this field one of the most dynamic and rapidly growing in biological sciences. This remarkable growth is stimulated by the influx of investigators from other disciplines such as biochemistry, genetics, molecular biology, microbiology, virology and various medical disciplines. These disciplines are so well interlinked with immunology that no immunological challenge can now be properly addressed without sophisticated applications of expertise of combinations of these disciplines. As a consequence, immunology has become a vast and rich field encompassing discoveries and outlooks that range from the highly clinical to the highly molecular. Although such perspectives may appear diverse, they are, in fact, extremely interdependent. The journal seeks to present a balanced overview of contemporary immunology and melds together different aspects of molecular immunology, immunobiology and clinical immunology.

Immunology is the branch of biomedical science that deals with the response of an organism to antigenic challenge and its recognition of what is self and what is not. It deals with the defense mechanisms including all physical, chemical and biological properties of the organism that help it to combat its susceptibility to foreign organisms, material, etc

Immunology has its origins in the study of how the body protects itself against infectious diseases caused by microorganisms, such as bacteria, viruses, protozoa, and fungi, and also parasitic organisms, such as helminth worms. Research / review articles deals with, among other things, the physiological functioning of the immune system in states of both health and disease; malfunctions of the immune system in immunological disorders (autoimmune diseases, hypersensitivities, immune deficiency, transplant rejection); the physical, chemical and physiological characteristics of the components of the immune system in vitro, in situ, and in vivo are of prime interest.





Associate Professor

Professor PhilenoPinge-Filho was born in São Paulo. He is an Associate Professor at the Londrina State University. Dr. Pinge-Filho is the team leader for the scientific group working with different aspects of immunopathology of Chagas disease. In 1988, Dr. Pinge-Filho received his BS in biological sciences from São Paulo State University (UNESP). In 1993, he received a MS in immunology from University of Campinas (UNICAMP). He joined the Department of Pathology at Londrina State University in 1997 as an Assistant Professor. In 1998, he received a PhD in Microbiology and Immunology from Federal University of São Paulo (UNIFESP-EPM). In 2003, he was spending a year as a visiting scientist at the University of Missouri, Columbia, USA. Dr. Pinge-Filho research is focused on elucidating the functional activity of phagocytes during T. cruziinfection, studying the role of eicosanoids in modulating the cell-mediated immunity. Dr. Pinge-Filho is a member of the Brazilian Society of Immunology (SBI), American Society for Investigative Pathology (ASIP) and American Society for Microbiology (ASM). Author of over 63 peer-review manuscripts.

Current Research

  • Chagas disease
  • Eicosanoids and immune response
  • Nitric oxide
  • Cytokines
  • Trained immunity

Interested topics

  • Host response to infectious disease
  • 2006- Instrument Grants Program -Turner BioSystems Modulus Multimode Reader Grant, Turner BioSystems - Sunnyvale, California (USA)
  • 2008- IMMUNORIB AWARDS Brazilian Society of Immunology
  • 2012- Marquis Who's Who, The Marquis Who's Who Publication Board to the Field of Lifes Sciences
  • 2015-Honorable Mention: Brazilian Society of Immunology at the XL Congress of the Brazilian Society of Immunology. Work: Parasite-accessory cell interactions in human Trypanosoma cruzi infection: effect of cyclooxygenase 1 and 2 inhibition.
  • 2016-Mention Honorable presentation of the work Physical training modulates the production of nitric oxide and cytokines improving the cardiovascular response and resistance to infection by Trypanosoma cruzi, IX South Symposium of Immunology - Fiocruz-Pr
  • Kevin L Fritsche – Missouri University, Columbia, USA

Phytomonas spp.: Modelo para Estudo de Processos Biológicos da Família Trypanosomatidae? In: Tópicos especiais em microbiologia [livro eletrônico].1 ed.Londrina : ADUEL, 2015, v.1, p. 148-165.ISBN: 9788578463595