International Journal of Immunology is a peer-reviewed open access journal that publishes original research articles as well as review articles in all areas of immunology. Immunology is a diverse and growing discipline that can be defined as the study of the tissues, cells and molecules involved in host defense mechanisms. Immunologists attempt to understand how the immune system develops, how the body defends itself against disease, and what happens when it all goes wrong. Priority is given to work that provides fundamental insight into the workings of the immune system. Areas covered include, but are not limited to, innate immunity and inflammation; development; immune receptors, signaling and apoptosis; antigen presentation; gene regulation and recombination; cellular and systemic immunity; vaccines; immune tolerance; autoimmunity and tumor immunology, microbial immunopathology; and transplantation.
The great advances in immunology in recent years make this field one of the most dynamic and rapidly growing in biological sciences. This remarkable growth is stimulated by the influx of investigators from other disciplines such as biochemistry, genetics, molecular biology, microbiology, virology and various medical disciplines. These disciplines are so well interlinked with immunology that no immunological challenge can now be properly addressed without sophisticated applications of expertise of combinations of these disciplines. As a consequence, immunology has become a vast and rich field encompassing discoveries and outlooks that range from the highly clinical to the highly molecular. Although such perspectives may appear diverse, they are, in fact, extremely interdependent. The journal seeks to present a balanced overview of contemporary immunology and melds together different aspects of molecular immunology, immunobiology and clinical immunology.
Immunology is the branch of biomedical science that deals with the response of an organism to antigenic challenge and its recognition of what is self and what is not. It deals with the defense mechanisms including all physical, chemical and biological properties of the organism that help it to combat its susceptibility to foreign organisms, material, etc
Immunology has its origins in the study of how the body protects itself against infectious diseases caused by microorganisms, such as bacteria, viruses, protozoa, and fungi, and also parasitic organisms, such as helminth worms. Research / review articles deals with, among other things, the physiological functioning of the immune system in states of both health and disease; malfunctions of the immune system in immunological disorders (autoimmune diseases, hypersensitivities, immune deficiency, transplant rejection); the physical, chemical and physiological characteristics of the components of the immune system in vitro, in situ, and in vivo are of prime interest.
We take great pleasure in welcoming you to our new journal, International Journal of Immunology. We have created this publication with the intention of providing a space for the generation of knowledge, dialogue, critique, debate, and collaboration among an international community of immunologists, pathologists, researchers, scholars, etc.
Our vision is to create a high-quality publication that will be relevant, challenging, thought-provoking, for graduate students, academic researchers and scholars. We welcome original research papers, reviews articles, case studies, book reviews, and works-in progress.
We look forward to welcoming your submissions.
1. Adaptive immunity 11. Cancer and Tumor Immunobiology
2. Immunologic Techniques 12. Cellular & Regional Immunology
3. Transplantation Immunology 13. Combining Cancer Immunotherapies
4. Computational Immunology 14. Allergy prevention and risk factors
5. Immunology 15. Nutritional Immunology
6. Immunotherapy 16. Clinical Immunology
7. Pediatric Immunology 17. Reproductive Immunology
8. Immune Tolerance 18. Fungal Immunology
9. Mucosal Immunology 19. Neuro Immunology
10. Immune Toxicology 20.Immunoinformatics and System
Immune Scientific Networks:
Immunology Leadership & Committees consider proposals for Special Issues Editors will return a decision on your proposal within Two weeks of receipt. To enrich our vision of making the scientific information available at an ease of access, Immunology Leadership & Committees initiated special issue for the open access journals. All the articles published under a special issue focuses on a single topic providing the complete information about the ongoing research providing more insight on an emphasized topic of research enabling the readers access wide forecasted information on a particular topic Issue.
Special Issue Proposals: Special Issue deals with focused research topics of high interest, falling under the scope of the Journal. Special Issues are the pool of articles under a current topic selected from the Ongoing Research under specific discipline. The aim of the Special Issue is to provide a platform for the researchers to understand the recent advancements and challenges in particular areas of research. These articles will provide an opportunity to the readers to understand and access the scientific information.
We encourage potential scientists to organize the Special Issue in their field of interests that fits within the Journal scope. This will provide an opportunity to increase the visibility of the Guest Editors. The Special Issue Titles may be from any basic and clinical area of Science, Technology and Medicine. People interested in publishing a special issue are advised to consider the following guidelines.
Your proposal should contain:
By submitting a Special Issue proposal to Immunology Leadership & Committees, you agree to abide by the Special Issue Editor Protocol should your proposal be accepted
Special issue articles are published immediately upon their acceptance and are released under upcoming regular issues. Special Issues are invited throughout the year. For more information or any queries about the special issues, please write us to firstname.lastname@example.org or email@example.com
Promoting Your Special Issue
Immunology Leadership & Committees will work with Guest Editors to increase the visibility of the Special Issue in the months leading up to the submission deadline and once it has been published.
What Immunology Leadership & Committees will do:
1. Immunology Leadership & Committees will circulate your Call for Papers to the Immune Editorial Board, targeted mailing lists, and relevant AoM listservs. It will also advertise your Call on the Immune websites and other social media platforms. It will re-issue the Call at appropriate intervals.
2. Once the Special Issue is published, announcements will be made to the Immune Editorial Board, targeted mailing lists, and relevant AoM listservs as well as on the Immune websites social media platforms.
3. Free access to the Special Issue will be made available in the website to Guest Editors and readers.
What is expected of Guest Editors?
1. We expect that Guest Editors will circulate the Call for Papers within their own personal networks, social media groups, and at any relevant conferences or workshops they may attend.
2. If it has not already been suggested as part of the proposal, consideration should be given to organizing a conference or workshop either to generate submissions or to aid in the development of submitted papers. A symposium or PDW at a well-known conference may also be considered.
3. We expect Guest Editors to identify up to 50 scholars for whom the Special Issue will be particularly relevant
If you have any queries, please contact Elena Griffin (firstname.lastname@example.org)
M.B.B.ch 1993 (From Mansoura Faculty of Medicine, Egypt)
M . Sc (Internal Medicine) 2000 (From Mansoura Faculty of Medicine, Egypt)
ILETs 2003 (From Kings school, Oxford University, UK )
MD, PhD (Internal Medicine) 2007 (From Benha University, Egypt)
INTERNATIONAL SOCIETY OF NEPHROLOGY FELLOWSHIP, TRANSPLANTATION IMMUNOLOGY 2002-2004 (OXFORD UNIVERSITY, UK).
1- THE BEST ORAL PRESENTATION:
Neural networks model for studying urea kinetics and prediction of the time of hemodialysis session in chronic hemodialysis patients.
A. Akl, M. Sobh, Y. Enab and J. Tattersall,
Urology & Nephrology Center, Mansoura, Egypt.
XXXVI Congress of the European Dialysis and Transplantation Association, Madrid, Spain, September, 6-9, 1999.
2- Holder of excellence prize in Nephrology and transplantation practice for the year 2001, The urology and Nephrology centre, Mansoura University, EGYPT (2001).
3- Internal Medicine science prize (Professor Fakhry), The Egyptian Academy of The Scientific Research and Technology, (2002).
4- Distinguished fellow’s Award, The International Society of Nephrology (ISN), Singapore, June 2005.
5- The Best Research Paper in transplantation, Prof. El Hussieni El Ghoniemi Prize, Arab society of nephrology and transplantation, Pan arab congress IX, Amman, Jordan April 2006.
6- Abdel Hamid Shoman foundation prize, Best Arab Medical research 2008, Amman, Jordan.
7- ISN EDUCATION AMBASSADOR 2013 and currently.
1- Akl AI, Sobh MA, Enab YM, Tattersall J.: Artificial intelligence: a new approach for prescription and monitoring of hemodialysis therapy. Am J Kidney Dis. 38(6):1277-83, 2001.
2- KJ Wood, S Luo, and A Akl: Regulatory T cells: potential in organ transplantation. Transplantation J. 77 (1): S6–S8, 2004.
3- Akl A, Luo S, Wood KJ: Induction of transplantation tolerance-the potential of regulatory T cells. Transplant immunology 14:225-230, 2005.
4- Sobh M, Neamatallah A, Sheashaa H, Akl A, Osman Y, Gad H, Eletrby M and Hegazy A: Sobh formula: A new formula for estimation of creatinine clearance in healthy subjects and patients with chronic renal disease. International Urology and Nephrology, 37:403-408, 2005.
5- Akl A, Jones ND, Rogers N, Bakr MA, Mostafa A, El Shehawy El M, Ghoneim MA and Wood KJ :An investigation to assess the potential of CD25(high)CD4 (+) T cells to regulate responses to donor alloantigens in clinically stable renal transplant recipients. Transplant Int. 2008 Jan; 21(1):65-73.(mini review)
6- Ahmed Akl, Amani mostafa and Mohamed Ahmed Ghoneim : Nomogram That Predicts Graft Survival Probability Following Living-Donor Kidney Transplant. Exp Clin Transplant. 2008 March; 1:30-36.
7- Akl A, Ismail AM, Ghoneim M. Prediction of graft survival of living-donor kidney transplantation: nomograms or artificial neural networks? . Transplantation. 2008 Nov 27; 86(10):1401-6.
8-El-Mekresh M, Akl A, Mosbah A, Abdel-Latif M, Abol-Enein H, Ghoneim MA. Prediction of survival after radical cystectomy for invasive bladder carcinoma: risk group stratification, nomograms or artificial neural networks? J Urol. 2009 Aug; 182(2):466-72.
9- Leone F, Akl A, Giral M, Dantal J, Blancho G, Soulillou JP, Cantarovich D. Six months anti-viral prophylaxis significantly decreased cytomegalovirus disease compared with no anti-viral prophylaxis following renal transplantation. Transpl Int. 2010 Sep; 23(9):897-906.
10- Gheith O, Ammar H, Akl A, Hamdy A, El-Saeed M, El-Salamouny T, Bakr MA, Ghoneim M. Spinal compression by brown tumor in two patients with chronic kidney allograft failure on maintenance hemodialysis. Iran J Kidney Dis. 2010 Jul;4(3):256-9.
11- Foucher Y, Daguin P, Akl A, Kessler M, Ladrière M, Legendre C, Kreis H, Rostaing L, Kamar N, Mourad G, Garrigue V, Bayle F, de Ligny BH, Büchler M, Meier C, Daurès JP, Soulillou JP, Giral M. A clinical scoring system highly predictive of long-term kidney graft survival. Kidney Int. 2010 Dec; 78(12):1288-94. PMID: 20861817.
12- Cantarovich D, De Amicis S, Akl A, Devys A, Vistoli F, Karam G, Soulillou JP. Posttransplant Donor-Specific Anti-HLA Antibodies Negatively Impact Pancreas Transplantation Outcome. Am J Transplant. 2011 Dec; 11(12):2737-46. PMID: 21906255.
13-Ehab W. Wafa, Ahmed A. Shokeir, Ahmed Akl, Nabil Hassan,Mohamed A. Fouda, Kalid El Dahshan, Mohamed A. Ghoneim. Effect of donor and recipient variables on the long-term live-donor renal allograft survival in children. Arab Journal of Urology 2011; 9:85-91.
14- Shebel HM, Akl A1, Dawood A, El-Diasty TA, Shokeir AA, Ghoneim MA. Power doppler sonography in early renal transplantation: does it differentiate acute graft rejection from acute tubular necrosis? Saudi J Kidney Dis Transpl. 2014 Jul;25(4):733-40.
15-Ghoneim MA1, Bakr MA, Refaie AF, Akl AI, Shokeir AA, Shehab El-Dein AB, Ammar HM, Ismail AM, Sheashaa HA, El-Baz MA. Factors affecting graft survival among patients receiving kidneys from live donors: a single-center experience. Biomed Res Int. 2013; 2013:912413. PMID: 23878820.
16-Degauque N, Ngono AE, Akl A, Lepetit M, Crochette R, Giral M, Lepourry J, Pallier A, Castagnet S, Dugast E, Guillot-Gueguen C, Jacq-Foucher M, Saulquin X, Cesbron A, Laplaud D, Nicot A, Brouard S, Soulillou JP. Characterization of antigen-specific B cells using nominal antigen-coated flow-beads. PLoS One. 2013 Dec 30; 8 (12):e84273.
17-Foucher Y1, Akl A, Rousseau V, Trébern-Launay K, Lorent M, Kessler M, Ladrière M, Legendre C, Kreis H, Rostaing L, Kamar N, Mourad G, Garrigue V, Morelon E, Buron F, Daurès JP, Soulillou JP, Giral M. An alternative approach to estimate age-related mortality of kidney transplant recipients compared to the general population: results in favor of old-to-old transplantations. Transpl Int. 2014 Feb; 27 (2):219-25. PMID: 24236869
18-Sarraj B, Ye J, Akl AI, Chen G, Wang JJ, Zhang Z, Abadja F, Abecassis M, Miller SD, Kansas GS, Ansari MJ. Impaired selectin-dependent leukocyte recruitment induces T-cell exhaustion and prevents chronic allograft vasculopathy and rejection. Proc Natl Acad Sci U S A. 2014 Aug 19;111(33):12145-50. doi: 10.1073/pnas.1303676111.
19-Fouad M, Abdellatif M, Hagag M, Akl A. Prediction of long term living donor kidney graft outcome: Comparison between different Machine Learning Methods. Ijct. 2014 Dec 9; 14(2):5419-31.
20-Nagib AM, Refaie AF, Akl AI, Neamatalla AH, Fouda MA, et al. (2015)
New Onset Diabetes Mellitus after Living Donor Renal Transplantation: A Unique
Pattern in the Egyptian Population. J Diabetes Metab 6: 519. doi:10.4172/2155-
21-Akl A, Neamatalla AH, Nagib AM, Bakr AM, Foda A (2015) Comparative Analysis of Long Term Survival of Pediatric and Adult Living Donor Renal Transplantation: Single Center 10 Years Experience. Urol Nephrol Open Access J 2(3): 00040. DOI: 10.15406/unoaj.2015.02.00040.
22- Maha Fouad, Mohamoud M Abd Ellatif, Mohamed Hagag, Ahmed Akl. Prediction of Long Term Living Donor Kidney Graft Outcome: Comparison Between Rule Based, Decision Tree and Linear Regression. IJARCST. 2015; 3(2):185.
23-Akl AI, Adel H, Rahim MA, Wafa EW, Shokeir AA. Outcome of glomerulonephritis in live-donor renal transplant recipients: A single-centre experience. Arab J Urol. 2015 Dec;13(4):295-305.
24- Ahmed Akl, Abdalla Sidahmed Mohamed, Naeim Salah, Mubarak Al-Shraim, Ahmed Nassar, Khalid Al-Alshiekh. Post Subtotal Thyroidectomy Calciphylaxis with Normal Calcium Phosphorus Product Following Kidney Transplantation: A Case Report. Urol Nephrol Open Access J 2016, 3(1): 00060.
25- Mohamed Alsaid, Essam Elsawy, Ahmed AKL, Ahmed Mosaad, Hany Adel, Mohamed Altayyeb, Yasser Farag, Ahmed Donia, Hussein Sheashaa, Mohamed Adel Bakr, Ayman Refaie. H1N1 Infection among Egyptian Renal Transplant Recipients. Urol Nephrol Open Access J 2016, 3(1): 00065.
26- Ahmed Akl, Mohamed A Megahd, Muhammed A El Hadedy, Ahmed H Neamatalla, Ayman M Nagib, Hussein A Sheashaa, Ehab W Wafa, Mohamed Ashraf Fouda, Ayman F. Refaie, Hossam Gad, Tarek El Diasty. Improvement of Renovascular Malignant Hypertension after Angioplasty. Urol Nephrol Open Access J 2016, 3(2): 00069.
27- Yasser Elsayed Matter, Ayman M Nagib, Omar E Lotfy, Ahmed Maher Alsayed, Ahmed F Donia, Ayman F Refaie, Ahmed I Akl, Mohamed Hamed Abbas, Mohammed M Abuelmagd, Hussein A Shaeashaa, Ahmed A Shokeir. Impact of Donor Source on the Outcome of Live Donor Kidney Transplantation: A Single Center Experience. Nephrourol Mon. 2016 May; 8(3): e34770.
28- Mohammed El-Rashedy, Ahmed Akl. Hemodialysis mining and patients intelligent clustering technologies. JESNT 2016, 16:124–130.
29- Elsaftawy MM, Akl A. Approach to Post Kidney Transplantation Anemia. Urol Nephrol Open Access J. 2017; 4(5): 00140.
30- Ahmed I. Akl, Hussein A. Sheashaa, Mona Abdel Rahim, Mohamed M. Abu-Elmagd, Muhammed A. El Hadedy, Ayman F. Refaie. Refractory CD20 Positive Cellular Rejection in Living Kidney Transplantation: A Case Report and review of Literature. Accepted in press Experimental & Clinical Transplantation Journal.