International Journal of Immunology is a peer-reviewed open access journal that publishes original research articles as well as review articles in all areas of immunology. Immunology is a diverse and growing discipline that can be defined as the study of the tissues, cells and molecules involved in host defense mechanisms. Immunologists attempt to understand how the immune system develops, how the body defends itself against disease, and what happens when it all goes wrong. Priority is given to work that provides fundamental insight into the workings of the immune system. Areas covered include, but are not limited to, innate immunity and inflammation; development; immune receptors, signaling and apoptosis; antigen presentation; gene regulation and recombination; cellular and systemic immunity; vaccines; immune tolerance; autoimmunity and tumor immunology, microbial immunopathology; and transplantation.

The great advances in immunology in recent years make this field one of the most dynamic and rapidly growing in biological sciences. This remarkable growth is stimulated by the influx of investigators from other disciplines such as biochemistry, genetics, molecular biology, microbiology, virology and various medical disciplines. These disciplines are so well interlinked with immunology that no immunological challenge can now be properly addressed without sophisticated applications of expertise of combinations of these disciplines. As a consequence, immunology has become a vast and rich field encompassing discoveries and outlooks that range from the highly clinical to the highly molecular. Although such perspectives may appear diverse, they are, in fact, extremely interdependent. The journal seeks to present a balanced overview of contemporary immunology and melds together different aspects of molecular immunology, immunobiology and clinical immunology.

Immunology is the branch of biomedical science that deals with the response of an organism to antigenic challenge and its recognition of what is self and what is not. It deals with the defense mechanisms including all physical, chemical and biological properties of the organism that help it to combat its susceptibility to foreign organisms, material, etc

Immunology has its origins in the study of how the body protects itself against infectious diseases caused by microorganisms, such as bacteria, viruses, protozoa, and fungi, and also parasitic organisms, such as helminth worms. Research / review articles deals with, among other things, the physiological functioning of the immune system in states of both health and disease; malfunctions of the immune system in immunological disorders (autoimmune diseases, hypersensitivities, immune deficiency, transplant rejection); the physical, chemical and physiological characteristics of the components of the immune system in vitro, in situ, and in vivo are of prime interest.




Sumit Ranjan Monu

Research Scientist

 Ph.D., Physiology and Pharmacology (Cardiovascular and Metabolic Disease Track), University of Toledo, USA,2010-2013 (All Honors, GPA: 3.8/4.0) with Dr.Nader Abraham (Mentor)
Thesis title: Heme-Oxygenase in myocardial infarction and cardiorenal syndrome.
 B.V.Sc & A.H. (equivalent to DVM), Madras Veterinary College, Tamil Nadu Veterinary and Animal Sciences University, India. 2003-2008 (Distinction. OGPA: 8.01/10)

 Research Scientist/Instructor- Hypertension and Vascular Research Division, Henry Ford Health System, Detroit. May 2016-Present.
 Post-doctoral Fellow- Hypertension and Vascular Research Division, Henry Ford Health System, Detroit. August 2013-April 2016
 Junior Research Fellow- Poultry Research Station, Tamil Nadu Veterinary and Animal Sciences University. Completed an extramural funded project on “Evaluation of animal by-products like Ossein, Sinews, Bone meal and Sludge on the performance of Broilers.” (October 2009 to June 2010.). Tamil Nadu Veterinary and Animal Sciences University, Chennai, India.

 American Heart Association. Kidney council young investigator award (Prize-$1000), Orlando, Florida 2016.
 Annual Henry Ford Health system Research symposium. Best poster award (Prize-$200). Detroit, Michigan.2015.
 Annual Henry Ford Medical Group Research symposium. Best poster award (Prize-$250). Detroit, Michigan 2017.

1.) Monu SR, Ren Y, Masjoan Juncos JX, Kutskill K, Wang H, Kumar N, Peterson EL, Carretero OA. Connecting tubule glomerular feedback mediates tubuloglomerular feedback resetting post unilaterally nephrectomy. (Am J Physiol Renal Physiol. 2017 Apr 19)
2.) Sumit Monu, Mani Maheshwari, Peterson EL, Carretero OA. Regulation of nephron afferent arteriole in obesity (Manuscript Under review Am J Physiol Renal Physiol. )
3.) Hong Wang, Cesar Romero, YiLin Ren, Sumit R. Monu, Kristopher Kutskill, Edward L. Peterson, Oscar A. Carretero. Luminal flow-stimulated superoxide participates in flow-induced connecting tubule glomerular feedback (Manuscript to be submitted June 2018)
4.) Nitin Kumar, Pablo Nakagawa, Branislava Janic, Cesar A. Romero, Morel E. Worou, Sumit R. Monu, Edward L. Peterson, Jiajiu Shaw, Frederick Valeriote, Elimelda M. Ongeri, Jean-Marie V. Niyitegeka, Nour-Eddine Rhaleb, and Oscar A. Carretero. The Anti-Inflammatory Peptide Ac-SDKP is released from Thymosin β4 by Renal Meprin and Prolyl Oligopeptidase. Am J Physiol Renal Physiol. 2016 May 15; 310(10):F1026-34
5.) Wang H, D'Ambrosio MA, Ren Y, Monu SR, Leung P, Kutskill K, Garvin JL, Janic B, Peterson EL, Carretero OA.nephron. Tubuloglomerular and connecting tubuloglomerular feedback during inhibition of various Na transporters in the nephron .Am J Physiol Renal Physiol. 2015 May 1; 308 (9), F1026-F1031.
6.) Sumit Monu, Paola Pesce, Komal Sodhi, Massimo Boldrin, Larisa Fedorova, David Sacerdoti, Stephen
Peterson, and Abraham NG. HO-1 Induction Improves Type-1 Cardiorenal Syndrome in Mice with
Impaired AngII-induced Lymphocyte Activation. Hypertension. 2013 Aug; 62(2):310-6
7.) Nitin P, Zhang F, Monu SR, Sodhi K,Bellner L,Lamon BD, ZhangY, Abraham NG,Nasjletti A.
Antioxidants Condition Pleiotropic Vascular Responses to Exogenous Hydrogen Peroxide: Role of
Modulation of Vascular TP receptors and the Heme Oxygenase System. Antioxid Redox Signal. 2013
Feb 10; 18(5): 471–480.
8.) Cao J, Sodhi K, Puri N, Monu SR, Rezzani R, Abraham NG. High fat diet enhances cardiac
abnormalities in SHR rats: Protective role of heme oxygenase-adiponectin axis. Diabetol Metab Syndr.
2011; 3: 37.

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