International Journal of Genome science is a peer-reviewed open acess journal that publishes original research articles as well as review articles in all areas of Genetics. As a journal that has evolved with the field that carries its name, Genomics focuses on the development and application of cutting-edge methods, addressing fundamental questions with potential interest to a wide audience. Our aim is to publish the highest quality research and to provide authors with rapid, fair and accurate review and publication of manuscripts falling within our scope. This journal provides the means for scientists, researchers, medical doctors, clinicians and biotechnologists to publish original rapid communications, full papers and timely state-of- the-art reviews encompassing the fundamental and applied research in all areas of the genome science and technology. Highest priority will be given to short communications reporting important new scientific and technological findings. Short communications on new findings with breakthrough results will be considered for accelerated publication though authors should provide a brief description why the manuscript be considered for fast tracking . International Journal of Genome science provides the means for scientists, researchers, medical doctors, clinicians and biotechnologists to publish original rapid communications, full papers and timely state-of- the-art reviews encompassing the fundamental and applied research in all areas of the genome science and technology. Highest priority will be given to short communications reporting important new scientific and technological findings. Short communications on new findings with breakthrough results will be considered for accelerated publication though authors should provide a brief description why the manuscript be considered for fast-tracking.

Genetics and genomics both play roles in health and disease. Genetics helps individuals and families learn about how conditions such as sickle cell anemia and cystic fibrosis are inherited in families, what screening and testing options are available, and, for some genetic conditions, what treatments are available. Genetics is a term that refers to the study of genes and their roles in inheritance - in other words, the way that certain traits or conditions are passed down from one generation to another. Genetics involves scientific studies of genes and their effects.




Michael Bukrinsky




Institute of Molecular Biology Award for Young Scientists


Institute of Virology Award for Young Scientists


USSR State Award for Young Scientists


GWU Distinguished Scientist Award


Oscar and Shoshana Trachtenberg Prize for GW Scholarship


Fellow of the American Heart Association



American Society for Microbiology


American Association for the Advancement of Science


New York Academy of Sciences


American Society for Biochemistry and Molecular Biology


International AIDS Society


  • Ad hoc reviewer for Nature, Nature Medicine, Nature Reviews, Journal of Experimental Medicine, Journal of Virology, Journal of Infectious Diseases, AIDS Research and Human Retroviruses, Journal of Immunology, Journal of Immunological Methods, Antiviral Research, European Journal of Immunology
  • Associate Editor, Frontiers in Bioscience, 1997 - 1999
  • Member of the Editorial Board, Virology, 2006 – present
  • Member of the Editorial Board, Retrovirology, 2006 – present
  • Member of the Editorial Board, The Open Medicine Journal, 2006 – present
  • Member of the Editorial Board, The Open Virology Journal, 2006 – present
  • Member of the Editorial Board, Cholesterol, 2006 – present
  • Member of the Editorial Board, Virology: Research and Treatment, 2011 - present
  • Editor, Advances in Virology, 2010 - present
  • Contributing Editor, Molecular Medicine, 2006 – present
  • Member of the Editorial Advisory Board, Recent patents on Anti-Infective Drug Discovery, 2006
  • Editor-in-Chief, Open AIDS Journal, 2010 - present


1.  Sabelnikov A.G., Bukrinsky M.I., Ilyashenko B.N. (1981).  Entry of double and single-stranded linear DNA into Ca2+-treated E. coli cells.  Mol. Biol. (Russian) 15:403-407.

2.  Bukrinsky M.I., Sabelnikov A.G. (1981).  Quantity of exogenous linear DNA absorbed by E. coli cells treated with Ca2+ cations.  Bull. Eksp. Biol. Med. (Russian) 5:594-596.

3.  Sabelnikov A.G., Bukrinsky M.I., Ilyashenko B.N. (1983).  Structural changes of exogenous DNAs in the process of homologous transformation of E. coli. Mol. Gen. Mikrobiol. Virusol. (Russian) 4:29-33.

4.  Bukrinsky M.I., Kramerov D.A. (1984).  Repetitive sequences of the A2 genome family in mice: size and transcription characteristics.  Dokl. Acad. Nauk SSSR (Russian) 178:231 -233.

5.  Bukrinsky M.I., Kramerov D.A. (1984).  Characteristics of the gene transcription of the intracisternal A-particles. Vopr. Virusol. (Russian) 3:345-350.

6.  Kramerov D.A., Bukrinsky M.I., Ryskov A.P. (1985).  DNA sequences homologous to long double-stranded RNA Transcription of intracisternal A-particle genes and major long repeat of the mouse genome.  Biochim. Biophys. Acta 826:20-29.

7.  Bukrinsky M.I., Kovtunenko L.V, Ulyashenko B.N. (1986).  Rapid method for analyzing the plasmid DNA of Bacillus cereus.  Mol. Gen. Mikrobiol. Virusol. (Russian) 9:22-24.

8.  Bukrinsky M.I., Barsov E.V., Karamov E.V. (1986).  Generation of HTLV-III-specific polypeptides in E. coli cells.  Vopr. Virusol. (Russian) 4:489-493.

9.  Bukrinsky M.I., Barsov E.V., Zhdanov V.M. (1986).  Cloning and expression of HTLV-III env gene fragment in Escherichia coli cells.  Dokl. Akad. Nauk SSSR (Russian) 289:498-499.

10.  Slepushkin V.A., Bukrinsky M.I. (1987).  Effective method of introducing plasmid DNA into eukaryotic cells by using liposomes for producing vaccinia virus recombinants.  Bull. Eksp. Biol. Med. (Russian) 10:478-480.

11.  Tentsov Y.Y., Bukrinsky M.I. (1987).  Detection of HTLV-III-specific sequences in T-lymphocyte lines by molecular hybridization.  Vopr. Virusol. (Russian) 2:219-221.

12.  Kovtunenko L.V., Bukrinsky M.I., Ilyashenko B.N. (1987).  Plasmid transformation of Bacillus cereus protoplasts.  Mol. Gen. Mikrobiol. Virusol. (Russian) 11:27-30.

13.  Bukrinsky M.I., Barsov E.V., Karamov E.V. (1988).  Use of recombinant proteins carrying antigenic determinants of the envelope proteins of AIDS virus in the diagnosis of acquired immunodeficiency syndrome.  Bull. Eksp. Biol. Med. (Russian) 5:577-578.

14.  Bukrinsky M.I., Zlobin A.Y., Arakelov S.A, Popov S.A., Chaplinskas S.A., Eremin V.F., Korneeva M.N., Nosik D.N., Rudneva I.A., Karamov E.V., Rytik P.G., Stakhanova V.M., Uryvaev L.V. (1988).  An analysis of blood sera by the immunoblot method using natural and recombinant antigens of the human immunodeficiency virus.  Vopr. Virusol. (Russian) 6:700-703.

15.  Popov S.A., Barsov E.V., Bukrinsky M.I., Zhdanov V.M. (1988).  Expression of gag gene of human immunodeficiency virus in recombinant vaccinia virus.  Mol. Gen. Mikrobiol. Virusol. (Russian) 9:36-39.

16.  Bukrinsky M.I., Barsov E.V., Shilov A.A. (1988).  Multicopy expression vector based on temperature-regulated lac repressor expression of human immunodeficiency virus env gene in E. coli.  Gene 70:415-417.

17.  Bukrinsky M.I., Briune I.R., Bartelemi L.L. (1989).  A study of strains of the human immunodeficiency virus type 1, isolated from 3 patients by a molecular hybridization method.  Vopr. Virusol. (Russian) 3:342-343.

18.  Barsov E.V., Bukrinsky M.I. (1989).  Construction of a novel vector for thermo- regulated gene expression.  Synthesis of a polypeptide carrying HIV antigenic determinants in E.coli cells.  Biotechnologia (Russian) 5:4-8.

19.  Bukrinsky M.I., Chaplinskas S.A., Syrtsev V.A., Bravkilene L.A., Philippov Yu.V. (1988).  Reactivity to gag- and env- related proteins in immunoblot assay is not necessarily indicative of HIV infection.  AIDS 2:405-406.

20.  Bukrinsky M.I., Syrtsev V.A., Popov S.A., Barsov E.V., Chaplinskas S.A., Karamov E.V. (1989).  False-positive sera do not react with human immunodeficiency virus (HIV) Gag encoded recombinant antigen.  J. Med. Virol. 27:72-75.

21.  Etkin A.F., Bukrinsky M.I. (1989).  Heterogeneity of the ARV-2 strain and natural isolates of the human immunodeficiency virus.  Arch. Virol. 108:271-277.

22.  Bukrinsky M.I., Etkin A.F. (1990).  Plus strand of the HIV provirus DNA is expressed at early stages of infection.  AIDS Res. Human Retroviruses 6:425-426.

23.  Bukrinsky M.I., Vzorov A.N., Bukrinskaya A.G. (1990).  Intracellular localization of recombinant vaccinia virus-produced HIV antigens and their use for confirmation of HIV seropositivity.  Acta Virol. 34:487-492.

24.  Vzorov A.N., Bukrinsky M.I., Grygoryev V.B., Tentsov Y.Y., Bukrinskaya A.G. (1991).  Highly immunogenic human immunodeficiency virus-like particles are produced by recombinant vaccinia virus infected cells.  AIDS Res. Human Retroviruses 7:29 36.

25.  Haggerty S., Dempsey M.P., Bukrinsky M.I., Guo L., Stevenson M. (1991).  Posttranslational modifications within the HIV-1 envelope glycoprotein which restrict virus assembly and CD4-dependent infection.  AIDS Res. Human Retroviruses 7:429-438.

26.  Bukrinsky M.I., Stanwick T.L., Dempsey M.P., Stevenson M. (1991).  Quiescent T Lymphocytes as an inducible reservoir in HIV-1 infection.  Science 254:423-427.

27.  Bukrinsky M.I., Sharova N.K., Dempsey M.P., Stanwick M.P., Bukrinskaya A.G., Haggerty S., Stevenson M. (1992).  Active nuclear transport of HIV-1 preintegration complexes.  Proc. Natl. Acad. Sci. U.S.A. 89:6580-6584.

28.  Bukrinsky M.I., Sharova N., McDonald T.L., Pushkarskaya T., Tarpley W.G., Stevenson M. (1993).  Association of integrase, matrix and reverse transcriptase antigens of human immunodeficiency virus type 1 with viral nucleic acids following acute infection.  Proc. Natl. Acad. Sci. U.S.A. 90:6125-6129.

29.  Bukrinsky M.I., Sharova N.K., Stevenson M. (1993).  Human immunodeficiency virus type 1 2-LTR circles reside in a nucleoprotein complex which is different from the preintegration complex.  J. Virol. 67:6863-6865.

30.  Bukrinsky M.I., Haggerty S, Dempsey M.P., Sharova N., Adzhubei A., Spitz L., Lewis P., Goldfarb D., Emerman M., Stevenson M. (1993).  A nuclear localization signal within HIV-1 matrix protein that governs infection of non-dividing cells.  Nature 365:666-669.

31.  Gulizia J., Dempsey M.P., Sharova N., Bukrinsky M.I., Spitz L., Goldfarb D., and Stevenson M. (1994).  Reduced nuclear import of human immunodeficiency virus type 1 preintegration complexes in the presence of a prototypic nuclear targeting signal.  J. Virol. 68:2021-2025.

32.  Heinzinger N.*, Bukrinsky M.I.*, Haggerty S., Ragland A., Kewalramani V., Lee M-A., Gendelman H., Ratner L., Stevenson M., Emerman M. (1994).  The HIV-1 Vpr protein is a component of the viral pre-integration complex which influences nuclear targeting of viral, nucleic acids in non-dividing host cells.  Proc. Natl Acad. Sci. U.S.A. 91:7311 -7315.

*Equal contribution.

33.  Emerman M., Bukrinsky M., and Stevenson M. (1994). HIV-1 infection of non-dividing cells.  Nature 369:107-108.

34.  Bukrinsky M., Nottet H.S.L.M., Schmidtmayerova H., Dubrovsky L., Flanagan C.R., Mullins M.E., Lipton S.A., and Gendelman H.E. (1995).  Regulation of nitric oxide synthase activity in HIV-1 monocytes: Implications for HlV-associated neurological diseases. J. Exp. Med. 181:735-745.

35.  Dubrovsky L., Ulrich P., Nuovo G.L., Manogue K.R., Cerami A., and Bukrinsky M. (1995).  Nuclear localization signal of HIV-1 as a novel target for therapeutic intervention.  Mol. Med. 1:217-230.

36.  Bianchi M., Ulrich P., Bloom O., Meistrell M., Zimmerman G.A., Schmidtmayerova H., Bukrinsky M., Donnelley T., Bucala R., Sherry B., Manogue K., Tortolani A.J., Cerami A., Tracey K.J. (1995).  An inhibitor of macrophage arginine transport and nitric oxide production (CNI-1493) prevents acute inflammation and endotoxin lethality.  Mol. Med. 1:254-266.

37.  Bukrinsky M., Manogue K., and Cerami A. (1995).  HIV results in the frame: Other approaches.  Nature 375:195-196 (Correspondence).

38.  Bianchi M., Bloom O., Raabe T., Cohen P.S., Chesney J., Sherry B., Schmidtmayerova H., Zhang X., Bukrinsky M., Ulrich P., Cerami A., and Tracey K. (1996).  Suppression of proinflammatory cytokines in monocytes by a tetravalent guanylhydrazone.  J. Exp. Med. 183:927-936.

39.  Schmidtmayerova H., Nottet H.S.L.M., Nuovo G., Raabe T., Flanagan C.R., Dubrovsky L., Gendelman H.E., Cerami A., Bukrinsky M., and Sherry B. (1996).  HIV-1 infection alters  chemokine peptide expression in human monocytes: Implications for recruitment of leukocytes into brain and lymph nodes.  Proc. Natl. Acad. Sci. U.S.A. 93:700-704.

40.  Thomas E.K., Connelly R.J., Pennathur S., Dubrovsky L., Haffar O.K., and Bukrinsky M. (1996).  Anti-idiotypic antibody to the V3 domain of gp120 binds to vimentin: A possible role of intermediate filaments in the early steps of HIV-1 infection cycle.  Viral Immunol. 9:73-87.

41.  Chao C.C., Hu S., Sheng W.S., Bu D., Bukrinsky M., and Peterson P.K. (1996).  Cytokine-stimulated astrocytes damage human neurons via a nitric oxide mechanism.  Glia 16:276-284.

42.  Bukrinsky M., Schmidtmayerova H., Zybarth G., Dubrovsky L., Sherry B., and Enikolopov G. (1996).  A critical role of nitric oxide in human immunodeficiency virus type 1-induced hyperresponsiveness of cultured monocytes.  Mol. Med. 2:460-468.

43.  Popov S., Dubrovsky, L., Lee M.-A., Pennathur S., Haffar O., Al-Abed Y., Tonge P., Ulrich P., Rexach M., Blobel G., Cerami A., and Bukrinsky M. (1996).  Critical role of reverse transcriptase in the inhibitory mechanism of CNI-H0294 on HIV-1 nuclear translocation.  Proc. Natl. Acad. Sci. U.S.A 93:11859-11864.

44.  Schmidtmayerova H., Sherry B., and Bukrinsky M. (1996).  Chemokines and HIV replication.  Nature 382:767.

45.  Schmidtmayerova H., Nuovo G., and Bukrinsky M. (1997).  Cell proliferation is not required for productive HIV-1 infection of macrophages.  Virology 232:379-384.

46.  Bukrinsky M., Sherry, B., Schmidtmayerova, H., Raabe, T., and Dubrovsky, L. (1997).  Differential regulation by nitric oxide: Production of macrophage inflammatory protein.  In “HIV and Cytokines”, M. Guenounou (ed.). Les Editions INSERM, Paris, pp. 89-97.

47.  Cohen P.S., Schmidtmayerova H., Dennis J., Dubrovsky L., Sherry B., Wang H., Bukrinsky M., and Tracey K.J. (1997).  The critical role of p38 MAP kinase in T cell HIV-1 replication.  Mol. Med. 3:339-346.

48.  Popov S., Rexach M., Zybarth G., Reiling N., Lee M.-A., Ratner L., Lane C.M., Moore M.S., Blobel G., and Bukrinsky M. (1998). Viral protein R regulates nuclear import of the HIV-1 pre-integration complex.  EMBO J. 17:909-917.

49.  Sherry B., Zybarth G., Alfano M., Dubrovsky L., Mitchell R., Rich D., Ulrich P., Bucala R., Cerami A., and Bukrinsky M. (1998).  Role of cyclophilin A in the uptake of HIV-1 by macrophages and T lymphocytes.  Proc. Natl. Acad. Sci. U.S.A. 95:1758-1763.

50.  Raabe T., Bukrinsky M., and Currie R.A. (1998). Relative contribution of transcription and translation to the induction of tumor necrosis factor-a by lipopolysaccharide.  J. Biol. Chem. 273:974-980.

51.  Popov S., Rexach M., Ratner L., Blobel G., and Bukrinsky M. (1998). Viral protein R regulates docking of the HIV-1 preintegration complex to the nuclear pore complex.  J. Biol. Chem. 273: 13347-13352.

52.  Haffar O.K., Smithgall M.D., Popov S., Ulrich P., Bruce A.G., Nadler S.G., Cerami A., and Bukrinsky M. (1998). CNI-H0294, a nuclear importation inhibitor of the human immunodeficiency virus type 1 genome, abrogates virus replication in infected activated peripheral blood mononuclear cells.  Antimicrob. Agents Chemother. 42: 1133-1138.

53.  Schmidtmayerova H., Alfano M., Nuovo G., and Bukrinsky M. (1998). Human immunodeficiency virus type 1 T-lymphotropic strains enter macrophages via a CD4- and CXCR4-mediated pathway: replication is restricted at a postentry level.  J. Virol. 72: 4633-4642.

54.  Alfano M., Schmidtmayerova H., and Bukrinsky M. (1998). Bacterial lipopolysaccharide is a potent inhibitor of HIV-1 replication in T lymphocytes and macrophages.  AIDS 12:10-12.

55.  Zybarth G., Reiling N., Schmidtmayerova H., Sherry B., and Bukrinsky M. (1999). Activation-induced resistance of human macrophages to HIV-1 infection in vitro.  J. Immunol. 162:400-406.

56.  Alfano M., Amella C.-A., Schmidtmayerova H., and Bukrinsky M. (1999). The B-oligomer of pertussis toxin deactivates CC-chemokine receptor 5 and blocks entry of M-tropic HIV-1 strains.  J. Exp. Med. 190:597-605 (Cover article).

57.  Franchin G., Zybarth G., Dai W.W., Dubrovsky L., Reiling N., Schmidtmayerova H., Bukrinsky M., and Sherry B. (2000). Lipopolysaccharide inhibits HIV-1 infection of monocyte-derived macrophages through direct and sustained downregulation of CCR5 receptors.  J. Immunol. 164:2592-2601.

58.  Haffar O.K., Popov S., Dubrovsky L., Agostini I., Tang H., Pushkarsky T., Nadler S.G., and Bukrinsky M. (2000). Two nuclear localization signals in the HIV-1 matrix protein regulate nuclear import of the HIV-1 pre-integration complex.  J. Mol. Biol. 299:359-368.

59.  Glushakova S., Dubrovsky L., Grivel J.-C., Haffar O.K., and Bukrinsky M. (2000). Small molecule inhibitor of HIV-1 nuclear import suppresses HIV-1 replication in human lymphoid tissue ex vivo: A potential addition to current anti-HIV drug repertoire.  Antiviral Res. 47:89-95.

60.  Sherry B., Schmidtmayerova H., Zybarth G., Dubrovsky L., Raabe T., and Bukrinsky M. (2000). Nitric oxide regulates MIP-1 expression in primary macrophages and T lymphocytes: implications for anti-HIV-1 response.  Mol. Med. 6:542-549.

61.  Agostini I., Popov S., Li J., Dubrovsky L., and Bukrinsky M. (2000). Heat-shock protein 70 can replace viral protein R of HIV-1 during nuclear import of the viral pre-integration complex.  Exp. Cell Res. 259:398-403.

62.  Alfano M., Pushkarsky T., Poli G., and Bukrinsky M. (2000). The B-oligomer of pertussis toxin inhibits HIV-1 replication at multiple stages.  J. Virol. 74:8767-8770.

63.  Alfano M., Vallanti G., Biswas P., Bovolenta C., Vicenzi E., Rappuoli R., Lazzarin A., Bukrinsky M.*, and Poli G*. (2001). The B-oligomeric subunit of pertussis toxin inhibits HIV replication in human macrophages and virus expression in chronically infected promonocytic U1 cells.  J. Immunol. 166:1863-1870.

*Equal contribution.

64.  Gujuluva C., Burns A.R., Pushkarsky T., Popik W., Berger O., Bukrinsky M., Graves M.C., and Fiala M. (2001). HIV-1 penetrates coronary artery endothelial cells by transcytosis.  Mol. Med. 7:169-176.

65.  Pushkarsky T., Zybarth G., Dubrovsky L., Yurchenko V., Guo H., Toole B., Sherry B., and Bukrinsky M. (2001). CD147 facilitates HIV-1 infection by interacting with virus-associated cyclophilin A.  Proc. Natl. Acad. Sci. U.S.A. 98:6360-6365.

66.  Yurchenko V., O'Connor M., Dai W.W., Guo H., Toole B., Sherry B., and Bukrinsky M. (2001). CD147 is a signaling receptor for cyclophilin B.  Biochem. Biophys. Res. Commun. 288:786-788.

67.  Pushkarsky T., Dubrovsky L., and Bukrinsky M. (2001). Lipopolysaccharide stimulates HIV-1 entry and degradation in human macrophages.  Endotox. Res. 7:271-276.

68.  Agostini I., Popov S., Hao T., Li J-H., Dubrovsky L., Chaika O., Chaika N., Lewis R., and Bukrinsky M. (2002). Phosphorylation of Vpr regulates HIV-1 nuclear import and macrophage infection.  AIDS Res. Human Retroviruses 18:283-288.

69.  Liu N.Q., Lossinsky A.S., Popik W., Li X., Gujuluva C., Kriederman B., Pushkarsky T., Bukrinsky M., Witte M., Weinand M., and Fiala M. (2002). Human immunodeficiency virus type 1 enters brain microvascular endothelia by macropinocytosis dependent upon lipid rafts and mitogen-activated protein kinase signaling pathway. J. Virol. 76:6689-6700.

70.  Yurchenko V., Zybarth G., O’Connor M., Dai W.W., Franchin G., Hao T., Guo H, Hung H.-C., Toole B., Gallay P., Sherry B., and Bukrinsky M. (2002). Active-site residues of cyclophilin A are crucial for its signaling activity via CD147. J. Biol. Chem. 277:22959-22965.

71.  Twu C., Liu N.Q., Popik W., Bukrinsky M., Sayre J., Roberts J., Rania S., Bramhandam V., Roos K.P., MacLellan W.R., and Fiala M. (2002). Cardiomyocytes undergo apoptosis in human immunodeficiency virus cardiomyopathy through mitochondrion- and death receptor-controlled pathways. Proc. Natl. Acad. Sci. U.S.A. 99:14386-14391.

72.  Iordanskiy S., Iordanskaya T., Quivy V., Van Lint C., and Bukrinsky M. (2002). B-Oligomer of pertussis toxin inhibits HIV-1 LTR-driven transcription through suppression of NF-kB p65 subunit activity. Virology 302:195-206.

73.  Di Marzio P., Sherry B., Thomas E.K., Franchin G., Schmidtmayerova H., and Bukrinsky M. (2003). b-Chemokine production in CD40L-stimulated monocyte-derived macrophages requires activation of MAPK signaling pathways. Cytokine 23:53-63

74.  Iordanskiy S., Zhao Y., DiMarzio P., Agostini I., Dubrovsky L., and Bukrinsky M. (2004). Heat-shock protein 70 exerts opposing effects on Vpr-dependent and Vpr-independent HIV-1 replication in macrophages. Blood 104:1867-1872.

75.  Bukrinsky M. and Zhao Y. (2004). Heat-shock proteins reverse the G2 arrest caused by HIV-1 viral protein R. DNA Cell Biol. 23:223-225.

76.  Iordanskiy S., Zhao Y., Dubrovsky S., Iordanskaya T., Chen M., Liang D., and Bukrinsky M. (2004). Heat-shock protein 70 protects cells from cell cycle arrest and apoptosis induced by HIV-1 viral protein R. J. Virol. 78:9697-9704.

77.  Benko Z., Liang D., Agbottah E., Hou J., Chiu K., Yu M., Innis S., Reed P., Kabat W., Elder R.T., Di Marzio P., Taricani L., Ratner L., Young P.G., Bukrinsky M., and Zhao R.Y. (2004). Antagonistic interactions between small heat shock proteins and HIV-1 viral protein R. J. Virol. 78:11016-11029.

78.  Yurchenko V, Pushkarsky T, Li JH, Dai WW, Sherry B and Bukrinsky M. (2005). Regulation of CD147 cell surface expression: involvement of the proline residue in the CD147 transmembrane domain. J. Biol Chem. 280:17013-17019.

79.  Arora K, Gwinn WM, Bower MA, Watson A, Okwumabua I, Macdonald HR, Bukrinsky M., and Constant SL. (2005). Extracellular cyclophilins contribute to the regulation of inflammatory responses. J. Immunol. 175:517-522.

80.  Pushkarsky T, Yurchenko V, Vanpouille C, Brichacek B, Vaisman I, Hatakeyama S, Nakayama KI, Sherry B, and Bukrinsky M. (2005). Cell surface expression of CD147/EMMPRIN is regulated by cyclophilin 60. J. Biol. Chem. 280:27866-27871.

81.  Haffar O, Dubrovsky L, Lowe R, Berro R, Kashanchi F, Godden J, Vanpouille C, Bajorath J, and Bukrinsky M. (2005). Oxadiazols: a new class of rationally designed anti-HIV compounds targeting nuclear localization signal of the viral matrix protein. J. Virol. 79:13028-13036.

82.  Iordanskiy S, Berro R, Altieri M, Kashanchi F, and Bukrinsky M. (2006). Intracytoplasmic maturation of the human immunodeficiency virus type 1 reverse transcription complexes determines their capacity to integrate into chromatin. Retrovirology 3:4.

83.  Brichacek B, Vanpouille C, Trachtenberg AJ, Pushkarsky T, Dubrovsky L, Martin G, Simon G, and Bukrinsky M. (2006). Long-term changes of serum chemokine levels in vaccinated military personnel. BMC Immunol. 7:21.

84.  Mujawar Z, Rose H, Morrow MP, Pushkarsky T, Dubrovsky L, Mukhamedova N, Fu Y, Dart A, Orenstein JM, Bobryshev YV, Bukrinsky M.*, and Sviridov D (2006). Human immunodeficiency virus impairs reverse cholesterol transport from macrophages. PLoS Biol. 4:e365.

*Corresponding author

85.  Gwinn WM, Damsker JM, Falahati R, Okwumabua I, Kelly-Welch A, Keegan AD, Vanpouille C, Lee JJ, Dent LA, Leitenberg D, Bukrinsky M., and Constant SL (2006). Novel approach to inhibit asthma-mediated lung inflammation using anti-CD147 intervention. J. Immunol. 177:4870-4879.

86.  Bukrinsky M. and Sviridov D (2007). HIV and cardiovascular disease: contribution of HIV-infected macrophages to development of atherosclerosis (commentary). PLoS Med. 4:e43.

87.  Benko Z, Liang D, Agbottah E, Hou J, Taricani L, Young PG, Bukrinsky M. and Zhao RY. (2007). Antagonistic interaction of HIV-1 Vpr with Hsf-mediated cellular heat shock response and Hsp16 in fission yeast (Schizosaccharomyces pombe). Retrovirology 4:16.

88.  Damsker JM, Bukrinsky M., Constant SL. (2007). Preferential chemotaxis of activated human CD4+ T cells by extracellular cyclophilin A. J. Leukoc. Biol. 82:613-618.

89.  Mukhamedova N, Fu Y, Bukrinsky M., Remaley A, Sviridov D. (2007). The role of different regions of ABCA1 in cholesterol efflux. Biochemistry 46:9388-9398.

90.  Liang D, Benko Z, Agbottah E, Bukrinsky M.*, Zhao RY. (2007). Anti-Vpr activities of heat-shock protein 27. Mol. Med. 13:229-239.

*Corresponding author

91.  Pushkarsky T, Yurchenko V, Laborico A, and Bukrinsky M. (2007). CD147 stimulates HIV-1 infection in a signal-independent fashion. Biochem. Biophys. Res. Com. 363:495-499.

92.  Yurchenko V, Xue Z, Sherry B and Bukrinsky M. (2008). Functional analysis of Leishmania major cyclophilin. Int. J. Parasitol. 38:633-639.

93.  Wu W, Kehn-Hall K, Pedati C, Zweier L, Castro I, Klase Z, Dowd CS, Dubrovsky L, Bukrinsky M., and Kashanchi F. (2008). Drug 9AA reactivates p21/Waf1 and Inhibits HIV-1 progeny formation. Virol J. 5:41.

94.  Rose H, Hoy J, Woolley I, Tchoua U, Bukrinsky M., Dart A, and Sviridov D. (2008). HIV infection and high density lipoprotein metabolism. Atherosclerosis 199:79-86.

95. Mukhamedova N, Escher G, D'Souza W, Tchoua U, Grant A, Krozowski Z, Bukrinsky M., and Sviridov D. (2008). Enhancing apolipoprotein A-I-dependent cholesterol efflux elevates cholesterol export from macrophages in vivo. J. Lipid Res. 49:2312-2322.

96.  Damsker JM, Okwumabua I, Pushkarsky T, Arora K, Bukrinsky M., and Constant SL. (2009). Targeting the chemotactic function of CD147 reduces collagen-induced arthritis. Immunology 126:55-62.

97.  Mukhamedova N, Rose H, Cui HL, Grant A, Tchoua U, Dart A, Bukrinsky M., Sviridov D. (2009). Antiretroviral compounds and cholesterol efflux from macrophages. Atherosclerosis 206:439-443.

98.  Kadiu I, Wang T, Schlautman JD, Dubrovsky L, Ciborowski P, Bukrinsky M., Gendelman HE. (2009). HIV-1 transforms the monocyte plasma membrane proteome. Cell Immunol. 258:44-58.

99.  Iordanskiy SN, Bukrinsky M. (2009). Analysis of viral and cellular proteins in HIV-1 reverse transcription complexes by co-immunoprecipitation. Methods Mol Biol. 485:121-34.

100. Li G, Bukrinsky M., Zhao RY. (2009). HIV-1 viral protein R (Vpr) and its interactions with host cell. Curr HIV Res. 7:178-183.

101. Schlegel J, Redzic JS, Porter CC, Yurchenko V, Bukrinsky M., Labeikovsky W, Armstrong GS, Zhang F, Isern NG, DeGregori J, Hodges R, Eisenmesser EZ. (2009). Solution characterization of the extracellular region of CD147 and its interaction with its enzyme ligand cyclophilin A. J Mol Biol. 391:518-535.

102. Malesević M, Kühling J, Erdmann F, Balsley MA, Bukrinsky M., Constant SL, Fischer G. (2010). A cyclosporin derivative discriminates between extracellular and intracellular cyclophilins. Angew Chem Int Ed Engl. 49:213-215.

103. Morrow MP, Grant A, Mujawar Z, Dubrovsky L, Pushkarsky T, Kiselyeva Y, Jennelle L, Mukhamedova N, Remaley AT, Kashanchi F, Sviridov D, Bukrinsky M. (2010). Stimulation of the liver X receptor pathway inhibits HIV-1 replication via induction of ATP-binding cassette transporter A1. Mol Pharmacol. 78:215-225.

104. Weinstein RS, Weinstein MM, Alibek K, Bukrinsky M., Brichacek B. (2010). Significantly reduced CCR5-tropic HIV-1 replication in vitro in cells from subjects previously immunized with Vaccinia Virus. BMC Immunol. 11:23.

105. Li G, Elder RT, Dubrovsky L, Liang D, Pushkarsky T, Chiu K, Fan T, Sire J, Bukrinsky M., Zhao RY. (2010). HIV-1 replication through hHR23A-mediated interaction of Vpr with 26S proteasome. PLoS One 5:e11371.

106. Asztalos BF, Mujawar Z, Morrow MP, Grant A, Pushkarsky T, Wanke C, Shannon R, Geyer M, Kirchhoff F, Sviridov D, Fitzgerald ML, Bukrinsky M., Mansfield KG. (2010). Circulating Nef induces dyslipidemia in simian immunodeficiency virus-infected macaques by suppressing cholesterol efflux. J Infect Dis. 202:614-623.

107. Mujawar Z, Tamehiro N, Grant A, Sviridov D, Bukrinsky M., Fitzgerald ML. (2010). Mutation of the ATP Cassette Binding Transporter A1 (ABCA1) C-Terminus Disrupts HIV-1 Nef Binding but Does Not Block the Nef Enhancement of ABCA1 Protein Degradation. Biochemistry 49:8338-8349.

108. Balsley MA, Malesevic M, Stemmy EJ, Gigley J, Jurjus RA, Herzog D, Bukrinsky M., Fischer G, Constant SL. (2010). A cell-impermeable cyclosporine a derivative reduces pathology in a mouse model of allergic lung inflammation. J Immunol. 185:7663-7670.

109. Stemmy EJ, Balsley MA, Jurjus RA, Damsker JM, Bukrinsky M., Constant SL. (2011). Blocking Cyclophilins in Chronic Phase of Asthma Reduces Leukocyte Persistence and Disease Reactivation. Am J Respir Cell Mol Biol. 45:991-998.

110. Trachtenberg A, Pushkarsky T, Heine S, Constant S, Brichacek B, Bukrinsky M. (2011). The level of CD147 expression correlates with cyclophilin-induced signaling and chemotaxis. BMC Res Notes 4:396.

111. Heine SJ, Olive D, Gao JL, Murphy PM, Bukrinsky M., Constant SL. (2011). Cyclophilin A cooperates with MIP-2 to augment neutrophil migration. J Inflamm Res. 4:93-104.

112. Dubrovsky L, Duyne RV, Senina S, Guendel I, Pushkarsky T, Sviridov D, Kashanchi F, Bukrinsky M. (2012). Liver X receptor agonist inhibits HIV-1 replication and prevents HIV-induced reduction of plasma HDL in humanized mouse model of HIV infection. Biochem Biophys Res Commun. 419: 95-98.

113. Cui HL, Grant A, Mukhamedova N, Pushkarsky T, Jennelle L, Dubrovsky L, Gaus K, Fitzgerald ML, Sviridov D, Bukrinsky M. (2012). HIV-1 Nef mobilizes lipid rafts in macrophages through a pathway that competes with ABCA1-dependent cholesterol efflux. J Lipid Res. 53: 696-708.

114. Santos S, Obukhov Y, Nekhai S, Bukrinsky M., Iordanskiy S. (2012). Virus-producing cells determine the host protein profiles of HIV-1 virion cores. Retrovirology 9:65.

115. Rose H, Low H, Dewar E, Bukrinsky M., Hoy J, Dart A, Sviridov D. (2013). The effect of HIV infection on atherosclerosis and lipoprotein metabolism: a one year prospective study. Atherosclerosis 229: 206-211.

116. Cui HL, Guo B, Scicluna B, Coleman BM, Lawson VA, Ellett L, Meikle PJ, Bukrinsky M., Mukhamedova N, Sviridov D, Hill AF. (2014). Prion infection impairs cholesterol metabolism in neuronal cells. J Biol Chem. 289: 789-802.

117. Jacob D, Hunegnaw R, Sabyrzyanova TA, Pushkarsky T, Chekhov VO, Adzhubei AA, Kalebina TS, Bukrinsky M. (2014). The ABCA1 domain responsible for interaction with HIV-1 Nef is conformational and not linear. Biochem Biophys Res Commun. 444: 19-23.

118. Cui HL, Ditiatkovski M, Kesani R, Bobryshev YV, Liu Y, Geyer M, Mukhamedova N, Bukrinsky M., Sviridov D. (2014). HIV protein Nef causes dyslipidemia and formation of foam cells in mouse models of atherosclerosis. FASEB J. 28: 2828-2839.

119. Jennelle L, Hunegnaw R, Dubrovsky L, Pushkarsky T, Fitzgerald ML, Sviridov D, Popratiloff A, Brichacek B, Bukrinsky M. (2014). HIV-1 protein Nef inhibits activity of ATP-binding cassette transporter A1 by targeting endoplasmic reticulum chaperone calnexin. J Biol Chem. 289: 28870-28884.

120. Brichacek B, Darwish C, Popratiloff A, Dubrovsky L, Bukrinsky M. (2014). HIV-1 infection of macrophages induces retention of cholesterol transporter ABCA1 in the endoplasmic reticulum. AIDS Res Hum Retroviruses 30: 947-948.

121. Ditiatkovski M, Neelisetti VN, Cui HL, Malesevic M, Fischer G, Bukrinsky M., Sviridov D. (2015). Inhibition of extracellular cyclophilins with cyclosporine analog and development of atherosclerosis in apolipoprotein E-deficient mice. J Pharmacol Exp Ther. 353: 490-495.

122. Ramezani A, Dubrovsky L, Pushkarsky T, Sviridov D, Karandish S, Raj DS, Fitzgerald ML, Bukrinsky M. (2015). Stimulation of Liver X Receptor Has Potent Anti-HIV Effects in a Humanized Mouse Model of HIV Infection. J Pharmacol Exp Ther. 354: 376-383.

123. Iordanskaia T, Malesevic M, Fischer G, Pushkarsky T, Bukrinsky M.*, Nadler E. (2015). Targeting extracellular cyclophilins ameliorates disease progression in experimental biliary atresia. Mol Med. In press. doi: 10.2119/molmed.2015.00076.

*Corresponding author

124. Siegel MO, Borkowska AG, Dubrovsky L, Roth M, Welti R, Roberts AD, Parenti DM, Simon GL, Sviridov D, Simmens S, Bukrinsky M.*, Fitzgerald ML. (2015). HIV infection induces structural and functional changes in high density lipoproteins. Atherosclerosis 243: 19-29.

*Corresponding author

125. Meikle P, Low H, Churchill MJ, Bukrinsky M, Sviridov D. (2015). Lipidomic dataset of plasma from patients infected with wild type and Nef-deficient HIV-1 strain. Data Brief. 6: 168-175.

126. Low H, Cheng L, Di Yacovo MS, Churchill MJ, Meikle P, Bukrinsky M, Hill AF, Sviridov D. (2016). Lipid metabolism in patients infected with Nef-deficient HIV-1 strain. Atherosclerosis 244: 22-28.

127. Siegel J, Darwish C, Popratiloff A, Bukrinsky M*, Brichacek B. (2016). Live Cell Imaging of ABCA1 Downregulation by HIV-1 Nef in an Experimental Model of HeLa ABCA1-GFP. AIDS Res Hum Retroviruses. 32: 872-873.

*Corresponding author

128. Low H, Mukhamedova N, Cui HL, McSharry BP, Avdic S, Hoang A, Ditiatkovski M, Liu Y, Fu Y, Meikle PJ, Blomberg M, Polyzos KA, Miller WE, Religa P, Bukrinsky M, Soderberg-Naucler C, Slobedman B, Sviridov D. (2016). Cytomegalovirus Restructures Lipid Rafts via a US28/CDC42-Mediated Pathway, Enhancing Cholesterol Efflux from Host Cells. Cell Rep. 16: 186-200.

129. Santos S, Obukhov Y, Nekhai S, Pushkarsky T, Brichacek B, Bukrinsky M*, Iordanskiy S. (2016). Cellular minichromosome maintenance complex component 5 (MCM5) is incorporated into HIV-1 virions and modulates viral replication in the newly infected cells. Virology 497: 11-22.

*Corresponding author

130. Hunegnaw R, Vassylyeva M, Dubrovsky L, Pushkarsky T, Sviridov D, Anashkina AA, Üren A, Brichacek B, Vassylyev DG, Adzhubei AA, Bukrinsky M. (2016). Interaction Between HIV-1 Nef and Calnexin: From Modeling to Small Molecule Inhibitors Reversing HIV-Induced Lipid Accumulation. Arterioscler Thromb Vasc Biol. 36: 1758-1771.

131. Mukhamedova N, Hoang A, Cui HL, Carmichael I, Fu Y, Bukrinsky M, Sviridov D. (2016).  Small GTPase ARF6 Regulates Endocytic Pathway Leading to Degradation of ATP-Binding Cassette Transporter A1. Arterioscler Thromb Vasc Biol. 36: 2292-2303.

132. Suttiprapa S, Rinaldi G, Tsai IJ, Mann VH, Dubrovsky L, Yan HB, Holroyd N, Huckvale T, Durrant C, Protasio AV, Pushkarsky T, Iordanskiy S, Berriman M, Bukrinsky MI*, Brindley PJ. (2016). HIV-1 Integrates Widely throughout the Genome of the Human Blood Fluke Schistosoma mansoni. PLoS Pathog. 12: e1005931.

*Corresponding author

133. Volotskova O, Dubrovsky L, Keidar M, Bukrinsky M. (2016). Cold Atmospheric Plasma Inhibits HIV-1 Replication in Macrophages by Targeting Both the Virus and the Cells. PLoS One 11: e0165322.

134. Pushkarsky T, Shilov E, Kruglova N, Naumann R, Brichacek B, Jennelle L, Sviridov D, Kruglov A, Nedospasov SA, Bukrinsky M. (2017). Short Communication: Accumulation of Neutral Lipids in Liver and Aorta of Nef-Transgenic Mice. AIDS Res Hum Retroviruses 33: 57-60.

135. Kuniholm MH, Liang H, Anastos K, Gustafson D, Kassaye S, Nowicki M, Sha BE, Pawlowski EJ, Gange SJ, Aouizerat BE, Pushkarsky T, Bukrinsky MI*, Prasad VR. (2017). Association of a 3' untranslated region polymorphism in proprotein convertase subtilisin/kexin type 9 with HIV viral load and CD4+ levels in HIV/hepatitis C virus coinfected women. AIDS 31: 2483-2492.