The Online International  Journal of Onco Scientific Networks & Oncology is a peer-reviewed open acess journal that publishes original research articles as well as review articles in all areas of Oncology. this practical journal also includes information on new products, new therapies and patient management, as well as reviews of the latest research. Cancer is a complex problem. The international effort to understand and control it involves clinicians trained in many branches of medicine and scientists from most biological disciplines, chemistry, pharmaceutical and physical sciences The International Online Journal of Cancer & Therapeutics exists to serve the needs of this diverse community, providing a forum for prompt communication of original and innovative research findings that have relevance to understanding the etiology of cancer and to improving the treatment and survival of patients.

The journal publishes important original studies, reviews, and perspectives within the major topic areas of biology of premalignancy, risk factors and risk assessment, early detection research, immunoprevention, and chemopreventive and other interventions, including the basic science behind them. This journal comprises preclinical, clinical and translational research, with special attention given to molecular discoveries and an emphasis on building a translational bridge between the basic and clinical sciences. Main focuses of interest include: systemic anticancer therapy (with specific interest on molecular targeted agents and new immune therapies), randomized trials (including negatives ones), top-level guidelines, and new fields currently emerging as key components of personalized medicine, such as molecular pathology, bioinformatics, modern statistics, and biotechnologies. Radiotherapy, surgery and pediatrics manuscripts can be considered if they display a clear interaction with one of the fields above or are paradigm-shifting.

Oncology is the diagnosis and treatment of cancers,including breast,prostate,colon,lung and ovarian cancers as well as brain tumors,leukemia,lymphoma and many other types of cancer.. A doctor who works in the field of oncology is called an oncologist. The primary regions of oncology are radiation, which is worried with radiation treatment, or radiotherapy; surgical, which is contained specialists who spend significant time in tumor evacuation; therapeutic, which manages disease drugs, including chemotherapy; and interventional, which includes interventional radiologists who have some expertise in insignificantly obtrusive picture guided tumor treatment.




Claudio Gambardella

General Surgeon

2004 – 2010 - Second University of Naples - Italy, Degree in Medicine and Surgery, Final vote: 110/110 cum laude. – Final thesis: “Role of Narrow Band Imaging and transanal surgery in unfit patients with rectal cancer”.
2010 - 2011 - State examination to practice the profession
2012 - 2017 - University of Campania “Luigi Vanvitelli” – Naples, Italy, General Surgery Residency Program (2011-2017), Division of General and Oncologic Surgery,University Department of Cardio-Thoracic and Respiratory Sciences, 
Final vote: 50/50 cum laude. – Final thesis: “Role of Electroporation in Locally Advanced Pancreatic Cancer (Stage III)” 
General Surgery Residency Program (2014 November – 2015)

General and Digestive Surgery Division at the “Hospital de la Santa Creu I Sant                Pau” – Barcelona
2017-PhD in Medical, Clinical and Experimental Sciences - University of Campania “Luigi Vanvitelli” – Naples, Italy,  University Department of Cardio-Thoracic and  Respiratory Sciences


  1. Gambardella A, Mocerino C, Taddeo M, Di Sarno G, Gambardella C, Santini L. Surgical risk assessment and therapeutic management in elderly patients with rectal cancer. G Gerontol. 2011;59:292-297.
  2. Conzo G, Docimo G, Ruggiero R, Napolitano S, Palazzo A, Gambardella C, Mauriello C, Tartaglia E, Cavallo F, Santini L. Surgical treatment of papillary thyroid carcinoma without lymph nodal involvement. G Chir. 2012 Oct;33(10):339-42.
  3. Conzo G, Mauriello C, Gambardella C, Napolitano S, Cavallo F, Tartaglia E, Santini L. Gallstone ileus: One-stage surgery in an elderly patient: One-stage surgery in gallstone ileus. Int J Surg Case Rep. 2013;4(3):316-8. doi: 10.1016/j.ijscr.2012.12.016.
  4. Conzo G, Docimo G, Mauriello C, Gambardella C, Esposito D, Cavallo F, Tartaglia E, Napolitano S, Santini L. The current status of lymph node dissection in the treatment of papillary thyroid cancer. A literature review. Clin Ter. 2013 Jul-Aug;164(4):e343-6. doi: 10.7417/CT.2013.1599.
  5. Conzo G, Docimo G, Pasquali D, Mauriello C, Gambardella C, Esposito D, Tartaglia E, Della Pietra C, Napolitano S, Rizzuto A, Santini L. Predictive value of nodal metastases on local recurrence in the management of differentiated thyroid cancer. Retrospective clinical study. BMC Surg. 2013 Oct 8;13 Suppl 2:S3. doi: 10.1186/1471-2482-13-S2-S3. Epub 2013 Oct 8.
  6. Conzo G, Gambardella C, Pasquali D, Ciancia G, Avenia N, Pietra CD, Napolitano S, Palazzo A, Mauriello C, Parmeggiani D, Pettinato G, Napolitano V, Santini L. Multifocal thoracic chordoma mimicking a paraganglioma. J Cancer Res Ther. 2013 Jul-Sep;9(3):497-9. doi: 10.4103/0973-1482.119312.
  7. Conzo G, Perna AF, Napolitano S, Mauriello C, Gambardella C, Satta E, Ciancia G, Capasso G, Santini L.Partial response to cinacalcet treatment in a patient with secondary hyperparathyroidism undergoing hemodialysis: a case report. J Med Case Rep. 2012 Dec 11;6(1):417. doi: 10.1186/1752-1947-6-417.
  8. Conzo G, Tartaglia E, Gambardella C, Mauriello C, Esposito D, Mascolo M, Russo D, Stornaiuolo G, Gaeta GB, Santini L. Suprarenal solitary fibrous tumor associated with a NF1 gene mutation mimicking a kidney neoplasm: implications for surgical management. World J Surg Oncol. 2014 Apr 7;12(1):87. doi: 10.1186/1477-7819-12-87.PMID: 24708790
  9. Conzo G, Pasquali D, Colantuoni V, Circelli L, Tartaglia E, Gambardella C, Napolitano S, Mauriello C, Avenia N, Santini L, Sinisi AA. Current concepts of pheochromocytoma. Int J Surg. 2014;12(5):469-74. doi: 10.1016/j.ijsu.2014.04.001.
  10. Conzo G, Calò PG, Sinisi AA, De Bellis A, Pasquali D, Iorio S, Tartaglia E, Mauriello C, Gambardella C, Cavallo F, Medas F, Polistena A, Santini L, Avenia N. Impact of prophylactic central compartment neck dissection on locoregional recurrence of differentiated thyroid cancer in clinically node-negative patients: A retrospective study of a large clinical series. Surgery. 2014 Jun;155(6):998-1005. doi:10.1016/j.surg.2014.02.010.
  11. Conzo G, Calò PG, Gambardella C, Tartaglia E, Mauriello C, Della Pietra C, Medas F, Cruz RS, Podda F, Santini L, Troncone G. Controversies in the surgical management of thyroid follicular neoplasms. Retrospective analysis of 721 patients. Int J Surg. 2014 May 22. pii: S1743-9191(14)00112-5. doi: 10.1016/j.ijsu.2014.05.013
  12. Conzo G, Pasquali D, Gambardella C, Della Pietra C, Esposito D, Napolitano S, Tartaglia E, Mauriello C, Thomas G, Pezzolla A, De Bellis A, Santini L, Sinisi AA. Long-term outcomes of laparoscopic adrenalectomy for Cushing disease. Int J Surg. 2014 May 23. pii: S1743-9191(14)00135-6. doi: 10.1016/j.ijsu.2014.05.036.
  13. Conzo G, Mauriello C, Docimo G, Gambardella C, Thomas G, Cavallo F, Tartaglia E, Napolitano S, Varriale R, Rossetti G, Fei L, Santini L. Clinicopathological pattern of lymph node recurrence of papillary thyroid cancer. Implications for surgery. Int J Surg. 2014;12 Suppl 1:S194-7. pii: S1743-9191(14)00109-5. doi: 10.1016/j.ijsu.2014.05.010.
  14. Conzo G, Della Pietra C, Tartaglia E, Gambardella C, Mauriello C, Palazzo A, Santini L, Fei L, Rossetti G, Docimo G, Perna A. Long-term function of parathyroid subcutaneous autoimplantation after presumed total parathyroidectomy in the treatment of secondary hyperparathyroidism. A clinical retrospective study. Int J Surg. 2014 May 24. pii: S1743-9191(14)00118-6. doi: 10.1016/j.ijsu.2014.05.019.
  15. Conzo G, Polistena A, Calò PG, Bononi P, Gambardella C, Mauriello C, Tartaglia E, Avenia S, Sanguinetti A, Medas F, de Toma G, Avenia N. Efficacy of combined treatment for anaplastic thyroid carcinoma: Results of a multinstitutional retrospective analysis. Int J Surg. 2014 May 24. pii: S1743-9191(14)00114-9. doi: 10.1016/j.ijsu.2014.05.015.
  16. Conzo G, Candela G, Tartaglia E, Gambardella C, Mauriello C, Pettinato G, Bellastella G, Esposito K, Santini L.Leiomyosarcoma of the thyroid gland: A case report and literature review. Oncol Lett. 2014 Apr;7(4):1011-1014. Epub 2014 Feb 4. PMID: 24944660
  17. Conzo G., Gambardella C., Mauriello C., Tartaglia E., Thomas G., Docimo G., Perna A., Capasso G., Santini L. Phenobarbital administration induces calcimimetic resistance and requires parathyroidectomy in secondary hyperparathyroidism hemodialysis patients. Min Chir 2014. [Epub ahead of print]
  18. Conzo G, Mauriello C, Gambardella C, Cavallo F, Tartaglia E, Napolitano S, Santini L. Isolated repeated anastomotic recurrence after sigmoidectomy. World J Gastroenterol. 2014 Nov 21;20(43):16343-8. doi: 10.3748/wjg.v20.i43.16343. Review. PMID: 25473193
  19. Conzo G, Gambardella C, Tartaglia E, Sciascia V, Mauriello C, Napolitano S, Orditura M, De Vita F, Santini L. Pancreatic fistula following pancreatoduodenectomy. Evaluation of different surgical approaches in the management of pancreatic stump. Literature review. Int J Surg. 2015 Sep;21 Suppl 1:S4-9. doi: 10.1016/j.ijsu.2015.04.088. Epub 2015 Jun 26. Review. PMID: 26118602
  20. Mauriello C, Napolitano S, Gambardella C, Candela G, De Vita F, Orditura M, Sciascia V, Tartaglia E, Lanza M, Santini L, Conzo G. Conservative management and parenchyma-sparing resections of pancreatic neuroendocrine tumors: Literature review. Int J Surg. 2015 Sep;21 Suppl 1:S10-4. doi: 10.1016/j.ijsu.2015.04.089. Epub 2015 Jun 26. Review. PMID: 26118605
  21. Mauriello C, Marte G, Canfora A, Napolitano S, Pezzolla A, Gambardella C, Tartaglia E, Lanza M, Candela G. Bilateral benign multinodular goiter: What is the adequate surgical therapy? A review of literature.Int J Surg. 2016 Apr;28 Suppl 1:S7-12. doi: 10.1016/j.ijsu.2015.12.041.
  22. Conzo G, Tartaglia E, Gambardella C, Esposito D, Sciascia V, Mauriello C, Nunziata A, Siciliano G, Izzo G, Cavallo F, Thomas G, Musella M, Santini L. Minimally invasive approach for adrenal lesions: Systematic review of laparoscopic versus retroperitoneoscopic adrenalectomy and assessment of risk factors for complications. Int J Surg. 2016 Apr;28 Suppl 1:S118-23. doi: 10.1016/j.ijsu.2015.12.042. Epub 2015 Dec 18. Review. PMID: 26708860
  23. Conzo G, Avenia N, Ansaldo GL, Calò P, De Palma M, Dobrinja C, Docimo G, Gambardella C, Grasso M, Lombardi CP, Pelizzo MR, Pezzolla A, Pezzullo L, Piccoli M, Rosato L, Siciliano G, Spiezia S, Tartaglia E, Tartaglia F, Testini M, Troncone G, Signoriello G. Surgical treatment of thyroid follicular neoplasms: results of a retrospective analysis of a large clinical series. Endocrine. 2017 Feb;55(2):530-538. PMID: 27075721
  24. Conzo G, Tartaglia E, Avenia N, Calò PG, de Bellis A, Esposito K, Gambardella C, Iorio S, Pasquali D, Santini L, Sinisi MA, Sinisi AA, Testini M, Polistena A, Bellastella G. Role of prophylactic central compartment lymph node dissection in clinically N0 differentiated thyroid cancer patients: analysis of risk factors and review of modern trends. World J Surg Oncol. 2016 May 17;14(1):149. doi: 10.1186/s12957-016-0879-4. Review. PMID: 27185169
  25. Gambardella C, Tartaglia E, Nunziata A, Izzo G, Siciliano G, Cavallo F, Mauriello C, Napolitano S, Thomas G, Testa D, Rossetti G, Sanguinetti A, Avenia N, Conzo G. Clinical significance of prophylactic central compartment neck dissection in the treatment of clinically node-negative papillary thyroid cancer patients. World J Surg Oncol. 2016 Sep 19;14(1):247. Review.
  26. Calò PG, Conzo G, Raffaelli M, Medas F, Gambardella C, De Crea C, Gordini L, Patrone R, Sessa L, Erdas E, Tartaglia E, Lombardi CP. Total thyroidectomy alone versus ipsilateral versus bilateral prophylactic central neck dissection in clinically node-negative differentiated thyroid carcinoma. A retrospective multicenter study. Eur J Surg Oncol. 2016 Oct 13. pii: S0748-7983(16)30931-3.
  27. Marotta V, Sciammarella C, Capasso M, Testori A, Pivonello C, Chiofalo MG, Gambardella C, Grasso M, Antonino A, Annunziata A, Macchia PE, Pivonello R, Santini L, Botti G, Losito S, Pezzullo L, Colao A, Faggiano A. Germline polymorphisms of the VEGF-pathway predict recurrence in non-advanced differentiated thyroid cancer. J Clin Endocrinol Metab. 2017 Feb 1;102(2):661-671.
  28. Mauriello C, Polistena A, Gambardella C, Tartaglia E, Orditura M, De Vita F, Santini L, Avenia N, Conzo G. Pancreatic stump closure after pancreatoduodenectomy in elderly patients: a retrospective clinical study. Aging Clin Exp Res. 2016 Nov 11.
  29. Calò PG, Medas F, Conzo G, Podda F, Canu GL, Gambardella C, Pisano G, Erdas E, Nicolosi A. Intraoperative neuromonitoring in thyroid surgery: Is the two-staged thyroidectomy justified? Int J Surg. 2017 May;41 Suppl 1:S13-S20.
  30. Accardo G, Conzo G, Esposito D, Gambardella C, Mazzella M, Castaldo F, Di Donna C, Polistena A, Avenia N, Colantuoni V, Giugliano D, Pasquali D. Genetics of medullary thyroid cancer: An overview. Int J Surg. 2017 May;41 Suppl 1:S2-S6.
  31. Ferraro F, Gambardella C, Testa D, Santini L, Marfella R, Fusco P, Lombardi CP, Polistena A, Sanguinetti A, Avenia N, Conzo G. Nasotracheal prolonged safe extubation in acute respiratory failure post-thyroidectomy: An efficacious technique to avoid tracheotomy? A retrospective analysis of a large case series. Int J Surg. 2017 May;41 Suppl 1:S48-S54.
  32. Gambardella C, Polistena A, Sanguinetti A, Patrone R, Napolitano S, Esposito D, Testa D, Marotta V, Faggiano A, Calò PG, Avenia N, Conzo G. Unintentional recurrent laryngeal nerve injuries following thyroidectomy: Is it the surgeon who pays the bill? Int J Surg. 2017 May;41 Suppl 1:S55-S59.
  33. Medas F, Erdas E, Gordini L, Conzo G, Gambardella C, Canu GL, Pisano G, Nicolosi A, Calò PG. Risk of malignancy in thyroid nodules classified as TIR-3A: What therapy? Int J Surg. 2017 May;41 Suppl 1:S60-S64.
  34. Parmeggiani D, Gambardella C, Patrone R, Polistena A, De Falco M, Ruggiero R, Cirocchi R, Sanguinetti A, Cuccurullo V, Accardo M, Avenia N, Docimo G, Tolone S, Bassi V, Docimo L, Conzo G. Radioguided thyroidectomy for follicular tumors: Multicentric experience. Int J Surg. 2017 May;41 Suppl 1:S75-S81.
  35. Marotta V, Sciammarella C, Chiofalo MG, Gambardella C, Bellevicine C, Grasso M, Conzo G, Docimo G, Botti G, Losito NS, Troncone G, De Palma M, Giacomelli L, Pezzullo L, Colao AA, Faggiano A. Hashimoto's thyroiditis predicts outcome in intrathyroidal papillary thyroid cancer. Endocr Relat Cancer. 2017 Sep;24(9):485-493. doi: 10.1530/ERC-17-0085. Epub 2017 Jul 10.
  36. Conzo G, Gambardella C, Candela G, Sanguinetti A, Polistena A, Clarizia G, Patrone R, Di Capua F, Offi C, Musella M, Iorio S, Bellastella G, Pasquali D, De Bellis A, Sinisi A, Avenia N. Single center experience with laparoscopic adrenalectomy on a large clinical series. BMC Surg. 2018 Jan 11;18(1):2.