International Journal of Immunology is a peer-reviewed open access journal that publishes original research articles as well as review articles in all areas of immunology. Immunology is a diverse and growing discipline that can be defined as the study of the tissues, cells and molecules involved in host defense mechanisms. Immunologists attempt to understand how the immune system develops, how the body defends itself against disease, and what happens when it all goes wrong. Priority is given to work that provides fundamental insight into the workings of the immune system. Areas covered include, but are not limited to, innate immunity and inflammation; development; immune receptors, signaling and apoptosis; antigen presentation; gene regulation and recombination; cellular and systemic immunity; vaccines; immune tolerance; autoimmunity and tumor immunology, microbial immunopathology; and transplantation.

The great advances in immunology in recent years make this field one of the most dynamic and rapidly growing in biological sciences. This remarkable growth is stimulated by the influx of investigators from other disciplines such as biochemistry, genetics, molecular biology, microbiology, virology and various medical disciplines. These disciplines are so well interlinked with immunology that no immunological challenge can now be properly addressed without sophisticated applications of expertise of combinations of these disciplines. As a consequence, immunology has become a vast and rich field encompassing discoveries and outlooks that range from the highly clinical to the highly molecular. Although such perspectives may appear diverse, they are, in fact, extremely interdependent. The journal seeks to present a balanced overview of contemporary immunology and melds together different aspects of molecular immunology, immunobiology and clinical immunology.

Immunology is the branch of biomedical science that deals with the response of an organism to antigenic challenge and its recognition of what is self and what is not. It deals with the defense mechanisms including all physical, chemical and biological properties of the organism that help it to combat its susceptibility to foreign organisms, material, etc

Immunology has its origins in the study of how the body protects itself against infectious diseases caused by microorganisms, such as bacteria, viruses, protozoa, and fungi, and also parasitic organisms, such as helminth worms. Research / review articles deals with, among other things, the physiological functioning of the immune system in states of both health and disease; malfunctions of the immune system in immunological disorders (autoimmune diseases, hypersensitivities, immune deficiency, transplant rejection); the physical, chemical and physiological characteristics of the components of the immune system in vitro, in situ, and in vivo are of prime interest.


committee

Members

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Dr. Gamil G.S. Zeedan

Associate Professor

1. Interest by human and animals viruses (RVFV, BEFV, H5N1 avian influenza viruses, Parapox viruses , Pox viruses and Equine influenza virus infection of different cell lines and primary cells with different viruses such as Influenza virus and Borna disease virus. Infection of embryonated chicken eggs with influenza viruses and other viruses….etc

2. Isolation and propagation viruses and Bacteria on Cell culture and different cell line culture like CEF, neuronal and other cells and culture and maintenance of continuous cell lines like VERO,MDCK, A549, C6, OL, PC12, SKNSH, MT-4, MOLT-4, …… etc and Cell cloning.

3. Virus Quantification and Identification: plaque assay, TCID50, LD50, EID50,HA and HI, hemadsorption, FFU, neutralization, Virus purification; ultracentrifugation and gradient centrifugation…..etc.

4. Protein Characterization: immunoflourescence; direct and indirect, immunoblotting; SDS-PAGE and Western blotting, immunohistochemistry, PAP staining, ELISA, …..etc.

5. Molecular Characterization: RNA and DNA purification, PCR and RT-PCR, in situ hybridization, Northern blotting. DNA cloning, PCR purification, plasmid purification for sequence analysis, in vitro transcription…..etc.

6. Bacterial culture and isolation, media preparation, staining and characterization, competent cell preparation, transfection.

7. Bioinformatics: sequence analysis, primer construction, protein structure analysis,

8. RNA analysis, phylogenetic analysis, using sequence analysis programs; Bio Edit, Genetyx, MEGA4….etc.

9. Others; preparation and purification of monoclonal antibodies and polyclonal antibodies. Histopathological analysis.

10. Excellent long experience working in BSL-2 and BSL-3 biosecurity levels with infections such as H5N1, Scrapie.

11.  Extensive knowledge of SPSS statistical programs

My research focuses on the Molecular Typing and immunological Studies of Viruses and Bactria of Animal Origin with Special Interest of Antibacterial and Antiviral Agents