International Journal of Immunology is a peer-reviewed open access journal that publishes original research articles as well as review articles in all areas of immunology. Immunology is a diverse and growing discipline that can be defined as the study of the tissues, cells and molecules involved in host defense mechanisms. Immunologists attempt to understand how the immune system develops, how the body defends itself against disease, and what happens when it all goes wrong. Priority is given to work that provides fundamental insight into the workings of the immune system. Areas covered include, but are not limited to, innate immunity and inflammation; development; immune receptors, signaling and apoptosis; antigen presentation; gene regulation and recombination; cellular and systemic immunity; vaccines; immune tolerance; autoimmunity and tumor immunology, microbial immunopathology; and transplantation.

The great advances in immunology in recent years make this field one of the most dynamic and rapidly growing in biological sciences. This remarkable growth is stimulated by the influx of investigators from other disciplines such as biochemistry, genetics, molecular biology, microbiology, virology and various medical disciplines. These disciplines are so well interlinked with immunology that no immunological challenge can now be properly addressed without sophisticated applications of expertise of combinations of these disciplines. As a consequence, immunology has become a vast and rich field encompassing discoveries and outlooks that range from the highly clinical to the highly molecular. Although such perspectives may appear diverse, they are, in fact, extremely interdependent. The journal seeks to present a balanced overview of contemporary immunology and melds together different aspects of molecular immunology, immunobiology and clinical immunology.

Immunology is the branch of biomedical science that deals with the response of an organism to antigenic challenge and its recognition of what is self and what is not. It deals with the defense mechanisms including all physical, chemical and biological properties of the organism that help it to combat its susceptibility to foreign organisms, material, etc

Immunology has its origins in the study of how the body protects itself against infectious diseases caused by microorganisms, such as bacteria, viruses, protozoa, and fungi, and also parasitic organisms, such as helminth worms. Research / review articles deals with, among other things, the physiological functioning of the immune system in states of both health and disease; malfunctions of the immune system in immunological disorders (autoimmune diseases, hypersensitivities, immune deficiency, transplant rejection); the physical, chemical and physiological characteristics of the components of the immune system in vitro, in situ, and in vivo are of prime interest.


committee

Members

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Bing Sun

Adjunct Professor

Prof. Bing Sun is burn from China. Now he is professor in Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences (in Shanghai, China) and was a chief, Lab of Molecular Immunology, He has MD and Ph.D. He has been working on Dendritic Cell maturation and T helper cell differentiation and their functions in autoimmune diseases. He has identified that Trim-30a, Dec2 and ECM1 are key molecules in controlling innate immunity and Th2 cell-mediated response (Nature Immunology 2008, 2009 and 2011). Since 2003 he has been working on viral ion channel protein, he has discovered 3a protein of SARS and P7 protein of HCV are an ion channel protein, which are important for viral life cycle and potential a drug target (PNAS 2006, Nature 2013). Currently the study is mainly to focus on the interaction of Th2 cells and ILC2 in asthma diseases. He was a funding director for Shanghai Institute of Pasteur in CAS and he established a whole program (2005 to 2016) for the institute to work on pathogen, immunology and vaccine. He was as a postdoctoral fellow at NIH,USA from 1994-1999.

Current Research

  • Th cell differentiation and innate lymphoid type 2 activation in asthma
  • Tumor immunotherapy
  • Single cell-PCR to generate full-human monoclonal antibody
  • Autoimmune disease
     

Interested topics

  • Dendritic cell maturation
  • ILC2 activation
  • Autoimmune disease
  • Engineering Ab technology
  • T helper cell differentiation
  • 2012 – Recipient, the shanghai Natural Science Award
  • 2013 – Recipient, National Natural Science Award
  • 2010 – Outstanding Teacher of Achievement, Chinese Academy of Sciences
  • 2010 – Certified Speaker, 14th international Immunology conference, Kobe,Japan
  • 2006- director, Shanghai Institute of Pasteur, Chinese Academy of Sciecens
  • 2005 – Joint Commission Advisory Panel ,Xingjiang Medical University,
  • 2003 – Outstanding Young Scientist of Achievement, National Science Fundation of China
  • 1994 – International Scholar, National Eye Institute, National Institute of Health,

 

  • NSFC grant“3a and its homologous proteins regulate coronaviruses release mechanism and drug target study” (2009.1-2011.12) work with Professor H. D. Klenk in Institut fuer Virologie, Marburg, Germany
  • MOST grant “The pathogenicity of RNA polymerase and NS1 suppression on IFN-α/ß production in different strains of avian flu viruses” (2009.1-2012.1) work with Professor Otto Haller in Department of Virology, University of Freiburg, Freiburg, Germany
  • EU project “FLUINNATE Innate immunity in influenza virus infection of mammalian airways ” work with professor Otto Haller and Georg Kochs in Department of Virology, University of Freiburg, Freiburg, Germany
  • NIH-NSFC joint project “Molecular mechanisms of T helper cell differentiation and migration regulated by transcription factors of T-bet and GATA3 in immune related diseases ” Work with Dr. Jinfang Zhu in NIAID, NIH,USA
  • NIH-NSFC joint project“Novel long intergenic non-coding RNAs and transcription factors in regulating the functions of Th2 cells and type 2 innate lymphoid cells in mouse models of asthma ” Work with Dr. Jinfang Zhu in NIAID, NIH,USA
  • Novo Nordisk-CAS joint project “Treatment of EAE with Extracellular matrix protein 1(ECM1) by inhibiting Th17 cell differentiation”
  • 1998 – American Association of immunologist, USA
  • 2003 – Chinese society of Immunology , China, vice president
  • 2008 – Federation of European Biochemical Societies