International Journal of Immunology is a peer-reviewed open access journal that publishes original research articles as well as review articles in all areas of immunology. Immunology is a diverse and growing discipline that can be defined as the study of the tissues, cells and molecules involved in host defense mechanisms. Immunologists attempt to understand how the immune system develops, how the body defends itself against disease, and what happens when it all goes wrong. Priority is given to work that provides fundamental insight into the workings of the immune system. Areas covered include, but are not limited to, innate immunity and inflammation; development; immune receptors, signaling and apoptosis; antigen presentation; gene regulation and recombination; cellular and systemic immunity; vaccines; immune tolerance; autoimmunity and tumor immunology, microbial immunopathology; and transplantation.

The great advances in immunology in recent years make this field one of the most dynamic and rapidly growing in biological sciences. This remarkable growth is stimulated by the influx of investigators from other disciplines such as biochemistry, genetics, molecular biology, microbiology, virology and various medical disciplines. These disciplines are so well interlinked with immunology that no immunological challenge can now be properly addressed without sophisticated applications of expertise of combinations of these disciplines. As a consequence, immunology has become a vast and rich field encompassing discoveries and outlooks that range from the highly clinical to the highly molecular. Although such perspectives may appear diverse, they are, in fact, extremely interdependent. The journal seeks to present a balanced overview of contemporary immunology and melds together different aspects of molecular immunology, immunobiology and clinical immunology.

Immunology is the branch of biomedical science that deals with the response of an organism to antigenic challenge and its recognition of what is self and what is not. It deals with the defense mechanisms including all physical, chemical and biological properties of the organism that help it to combat its susceptibility to foreign organisms, material, etc

Immunology has its origins in the study of how the body protects itself against infectious diseases caused by microorganisms, such as bacteria, viruses, protozoa, and fungi, and also parasitic organisms, such as helminth worms. Research / review articles deals with, among other things, the physiological functioning of the immune system in states of both health and disease; malfunctions of the immune system in immunological disorders (autoimmune diseases, hypersensitivities, immune deficiency, transplant rejection); the physical, chemical and physiological characteristics of the components of the immune system in vitro, in situ, and in vivo are of prime interest.


committee

Members

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Alok Das Mohapatra

Research Associate

2011 Doctor of Philosophyin Life science (Cellular Immunology)Utkal University, Orissa, India.

2000 Master of Science in Microbiology Orissa University of Agriculture and Technology(OUAT),India.

 

-Studying the interaction between tumor cells and host immune system during early     tumorigenesis.                          

-Understanding the antitumor properties of host immune system and explore how this can be       exploited for the immunotherapeutic intervention against cancer.

-Processing and presentation of live tumor cell associated antigens by antigen presenting cells.   

-Evaluating the potential of induced programmed cell death in cancer cells in anti-cancer therapy.

-Studying the role  of adjuvants in determining the efficacy of vaccines

-Exploring alternative approaches to  vaccine design in cancer and infectious diseases

2015 Travel awardfororal presentation in AmericanAssociation of Immunologymeeting, New Orleans,LA, USA.

 

 1-Tumor Biology (Springer Publication).

 2-PLOS Neglected Tropical Diseases (PLOS publication).

 3-Journal of Plant Biochemistry and Biotechnology (Springer Publication).

 4-BMC Oral biology (Biomed Central Publication).

 5-Journal of food safety(Wiley online Publication).

 6-Food borne pathogens and disease (Mary Ann Liebert,Inc. Publication, USA)

 7-Indian Journal of Geo-Marine Sciences (NISCAIR Publication, INDIA). 

 

#Henry Journal of Immunology & Immunotherapy

#Gavin Journal of Vaccines Immunology and Immunopathology

1.Alok Das Mohapatra, Santosh K Panda, Anjan K Pradhan,Birendra K Prusty, Ashok K Satapathy,Balachandran Ravindran. Filarial antigens induce apoptosis of human monocytes through TLR4.Journalof Infectious Diseases.2014 doi:10.1093/infdis/jiu208.

2.Madhumita Panda,Prakash K Sahoo, Alok Das Mohapatra,Somya Kanti Dutta,Pravat K thatoi, Rina Trpathy,Bidyut K Das, Ashok K Satapathy, Balachandran Ravindran. Decreased prevalence of sepsis but not mild or severe P. falciparum malaria is associated with pre-existing filarial infectionParasite and vectors. 2013, 6:203.                                      

3. Kasturi Bala Nayak,Nivedita Kuila,Alok Das Mohapatra,Aditya kumar Panda,Soumen ChakrabortyEVI1 targets ΔNp63 and up regulates the cyclindependent kinase inhibitor p21 independent of p53 to delay cell cycle   progression and cell proliferation in colon cancer cells. International Journal of Biochemistry. & Cell   biology2013, 45(8):1568-76.                                                                                                                                 

4.Alok Das Mohapatra,Sunil kumar,Ashok kumar Satapathy,Balachandran Ravindran.Caspase dependent  programmed cell death in developing embryos: a potential target for therapeutic intervention against pathogenic nematodes PLoS Neglected Tropical Diseases09/2011; 5(9):e1306.

5.Anjan K Pradhan,Alok Das Mohapatra,Kasturi Bala Nayak, Soumen Chakraborty.Acetylation of  the  protooncogene EVI1 abrogates Bcl-xL promoter binding and induces apoptosis. PloS  One.01/2011;   6(9):e25370.

6. Pranati Sar,Rosalima Peter, Bandita Rath, Alok Das Mohapatra, Sandip K Mishra. 3,3’5 Triiodo  thyronine   induces apoptosis in human breast cancer MCF-7 cells, repressing SMP30 expression through  negative thyroid   response elements. Plos One. 01/20116(6):e20861.                                                                                                                                          

7.JayantaKumar Patra, Alok Das Mohapatra, Sakti Kanta Rath,Nabin Kumar Dhal,Hrudayanath Thatoi. Screeening of antioxidant and antifilarial activity of leaf extracts of Excoecaria agallocha L. International Journal of Integrative Biology 2009,7(1), 9-15.  

8.Bikash Ranjan Sahu,Alok Das Mohapatra Arindam Majumder, Pradip K Das, Balachandran Ravindran “A  Flow  cytometry Based method for studying Embryogenesis and Immune reactivity to embryonic stages of filarial   parasites.Filaria journal,2005,4:11.

9. A Das Mohapatra,C.C. Rath S.K.Dash and R.K.Mishra. Microbiological Evaluation of   Popular StreetFoods in Bhubaneswar” Journal of FoodScience and Technology 2002, 39 (1), 59-61.                 .    

10.Sahar Al Seesi, Alok Das Mohapatra, Arpita Pawashe,Ion I Mandoiu, Fei Duan.Finding Neoepitopes in Mouse Genome for Personalized Cancer Immunotherapy.(In Press).