The International Online Journal of Cancer & Therapeutics is a peer-reviewed open acess journal that publishes original research articles as well as review articles in all areas of Oncology. this practical journal also includes information on new products, new therapies and patient management, as well as reviews of the latest research. Cancer is a complex problem. The international effort to understand and control it involves clinicians trained in many branches of medicine and scientists from most biological disciplines, chemistry, pharmaceutical and physical sciences The International Online Journal of Cancer & Therapeutics exists to serve the needs of this diverse community, providing a forum for prompt communication of original and innovative research findings that have relevance to understanding the etiology of cancer and to improving the treatment and survival of patients.

The journal publishes important original studies, reviews, and perspectives within the major topic areas of biology of premalignancy, risk factors and risk assessment, early detection research, immunoprevention, and chemopreventive and other interventions, including the basic science behind them. This journal comprises preclinical, clinical and translational research, with special attention given to molecular discoveries and an emphasis on building a translational bridge between the basic and clinical sciences. Main focuses of interest include: systemic anticancer therapy (with specific interest on molecular targeted agents and new immune therapies), randomized trials (including negatives ones), top-level guidelines, and new fields currently emerging as key components of personalized medicine, such as molecular pathology, bioinformatics, modern statistics, and biotechnologies. Radiotherapy, surgery and pediatrics manuscripts can be considered if they display a clear interaction with one of the fields above or are paradigm-shifting.

Oncology is the diagnosis and treatment of cancers,including breast,prostate,colon,lung and ovarian cancers as well as brain tumors,leukemia,lymphoma and many other types of cancer.. A doctor who works in the field of oncology is called an oncologist. The primary regions of oncology are radiation, which is worried with radiation treatment, or radiotherapy; surgical, which is contained specialists who spend significant time in tumor evacuation; therapeutic, which manages disease drugs, including chemotherapy; and interventional, which includes interventional radiologists who have some expertise in insignificantly obtrusive picture guided tumor treatment.


committee

Members

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Mohammad S Mubarak

Professor

Professor Mubarak received his Ph.D. degree from Indiana University, Bloomington, USA in 1982. He served as the chairman of the department of chemistry at The University of Jordan and the Vice Dean of the Faculty of Science for several years. He is also an Adjunct professor of Chemistry at Indiana University, Bloomington (USA) since 2009. In addition to electrochemistry, Professor Mubarak’s research program is broadly based on synthetic organic chemistry, especially synthesis of compounds with expected biological activity, medicinal chemistry, and drug design and discovery. He is the author and coauthor of more than 180 research papers and reviews published in peer-reviewed journals in addition to chapters published in specialized books. He has also supervised 39 theses and dissertations.

  • Ph.D. Chemistry, July 1982.  Indiana University, Bloomington, IN. 47405, U.S.A. (GPA 3.93/4)
  • M.Sc. Chemistry, February 1978. The University of Jordan, Amman, Jordan   Average: 87.2% (TOP OF CLASS)
  • B.Sc. Chemistry with a minor in Education, February 1976. The University of Jordan, Amman, Jordan.  Average: 78.9% (TOP OF CLASS).

 

  • Synthetic organic chemistry in its very broadest sense. Generally, our efforts are focused on the preparation of organic compounds and new heterocyclic compounds that may display biological activity and may have pharmacological significance. Present studies are directed toward the synthesis of new agents that may have anti-parasitic, antimicrobial, and antitumor activities. Several spectroscopic techniques, such as NMR spectroscopy, FTIR, Mass spectrometry, will be utilized for the identification of the new products, in addition to microanalysis. Examples of research projects ongoing in our laboratory include the following: (1) Synthesis of new coumarin derivatives that may have some antitumor activities. (2) Development of synthetic strategies for the preparation of new heterocyclic compounds that incorporate imidazole moieties.
  • Synthesis of new chelating polymers that may have applications in the removal of heavy metal ions from the aquatic environment. In addition, our research also focuses on immobilizing chelating groups on commercially available resins; these immobilized groups could be very effective in removing heavy metal ions from aqueous solutions
  • Organic electrochemistry; use of electroanalytical, methods (cyclicVoltammetry and coulometry) to investigate the mechanisms of reduction and oxidation processes involving organic and organometallic species at various electrodes in nonaqueous solvents. This kind of work is normally done in collaboration with Indiana University, Bloomington, In. USA.
  • Medicinal chemistry, natural products, and medicinal plants.

 

  • Recipient of the 2006/2007 distinguished researcher award from University of Jordan.
  • Recipient of an award from University of Jordan for bringing external fund from the EU, 2006/2007.
  • Jordan Scopus Award of Most Active author at the University of Jordan, March 31, 2009, under the patronage of HRH Princess Sumaya Bint El Hassan.
  • Adjunct Professor of Chemistry, Indiana University, Bloomington, In. 47405, USA. March, 2009-March 2012.
  • Honorary member of editorial board of Der Pharma Chemica, online Journal for Chemistry.
  • Recipient of distinguished researcher award from the University of Jordan, for 2009
  • Recipient of distinguished researcher award from the University of Jordan, for 2010
  • Recipient of distinguished researcher award from the University of Jordan, for 2011.
  • The Ali Mango award for the distinguished scientist of the year 2011, awarded by Hamdi Mango Center of Scientific Research, The University of Jordan, on April 26, 2012.

1. Jarrar, A. A.; El-Zaro, R. A.; Mubarak, M. S. "Kinetics of Oxidation of Benzoins by Hexacyano-ferrate (III) in an Alkaline Medium" Dirasat-Natural Sciences. 1979, 6, 7-18.

2. Mubarak, M. S.; Peters, D. G. "Electrochemiscal Reduction of 2-Iodooctane and 2-Bromooctane at Mercury Cathodes in Dimethylformamide" J. Org. Chem. 1982, 47, 3397-3403.

3. Mubarak, M. S.; Peters, D. G. "Electrochemical Reduction of Diphenyliodonium Salts and Phenyl Mercuric Halides in Dimethylformamide" J. Electroanal. Chem. Interfacial Electrochem. 1983, 152, 183-196.

4. Vieira, K. L.; Mubarak, M. S.; Peters, D. G. "Use of Deuterium Labeling to Assess the Roles of Tetramethylammonium Cation, Dimethylformamide, and Water as Proton Donors for Electro-generated tert-Butyl Carbanions: Evidence for the Formation of an Ylide (Trimethylammonium Methylide)" J. Am. Chem. Soc. 1984, 106, 5372-5373.

5. Mubarak, M. S.; Peters, D. G. " Electrochemical Reduction of Asymmetrically Substituted Diphenyliodonium Salts at Mercury Cathodes in Dimethylformamide" J. Org. Chem. 1985, 50, 673-677.

6. Cleary, J. A.; Mubarak, M. S.; Vieira, K. L.; Anderson, M. R.; Peters, D. G. "Electrochemical Reduction of Alkyl Halides at Vitreous Carbon Cathodes in Dimethylformamide" J. Electroanal. Chem. Interfacial Electrochem. 1986198, 107-124.

7. Mubarak, M. S.; Peters, D. G. "Use of Nafion Coatings on Glassy Carbon Electrodes as Localized Sources of Protons for Electrogenerated Redical-Anions in Acetonitrile" J. Electroanal. Chem. Interfacial Electrochem. 1989, 273, 283-292.

8. Mubarak, M. S.; Karras, L. L.; Murcia, N. S.; Bart, J. C.; Stemple, J. Z.; Peters, D. G. "Electrochemical Reduction of 4-Iodo- and 4-Bromoanisole at Mercury and Carbon Cathodes in Dimethyl-formamide" J. Org. Chem. 1990, 55, 1065-1070.

9. Mubarak, M. S.; Nguyen, D. D.; Peters, D. G. "Electrochemical Reduction and Intramolecular Cyclization of 6-Iodo-1-phenyl-1-hexyne at Vitreous Carbon Cathodes in Dimethylformamide" J. Org. Chem. 1990, 55, 2648-2652.

10. Urove, G. A.; Mubarak, M. S.; Peters, D. G. "Electrolytic Reductions of Heptanoyl Chloride, Phthaloyl Dichloride, and Benzoyl Chloride at Carbon and Mercury Cathodes in Acetonitrile" In Electroorganic Synthesis-Festschrift for Manuel M. Baizer, R. D. Little and N. L. Weinberg, eds., Marcel Dekker, New York, 1991, pp. 91-98.

11. Urove, G. A.; Peters, D. G.; Mubarak, M. S. " Production of Aldehydes via Electrochemical Reduction of Acyl Halides at Mercury and Carbon Cathodes in Acetonitrile" J. Org. Chem. 1992, 57, 786-790.

12. Mubarak, M. S.; Peters, D. G. "In Situ Electrogeneration of [2,2'- Ethylenebis(nitriblomethylidyne)diphenolato]nickelate (I)-Nickel (I) Salen-As a Catalyst for Reductive Intramolecular Cyclizations of 6-Iodo- and 6-Bromo-1-phenyl-1-hexyne" J. Electroanal. Chem. Interfacial Electrochem. 1992, 332, 127-134.

13. Mubarak, M. S.; Urove, G. A.; Peters, D. G. "Electrochemical Reduction of Phenylacetyl Chloride and Hydrocinnamoyl Chloride at Mercury Cathodes in Acetonitrile" J. Electroanal. Chem. Interfacial Electrochem. 1993, 350, 205-216.

14. Mubarak, M. S.; Peters, D. G. "Quantitative Electrochemical Reduction of 1-Adamantanecarbonyl Chloride to 1-Adamantanecarboxaldehyde at Carbon and Mercury Cathodes in Acetonitrile" J. Electrochem. Soc. 1995, 142, 713-715.

15. Mubarak, M. S.; Peters, D. G. "Electrochemical Reduction of 1,6- Dihalohexanes at Carbon Cathodes in Dimethylformamide" J. Org. Chem. 1995, 60, 681-685.

16. Mubarak, M. S.; Peters, D. G. "Homogeneous Catalytic Reduction of ,- Dihaloalkanes with Electrogenerated Nickel(I) Salen" J. Electroanal. Chem. Interfacial Electrochem. 1995, 388, 195-198.

17. Peters, D. G.; Dahm, C. E.; Bhattacharya, D.; Butler, A. L.; Mubarak, M. S. "Use of Transition-Metal Complexes as Homogeneous and Polymer-Based Catalysts for Electroorganic Synthesis" In Novel Trends in Electroorganic Synthesis, S. Torii, ed., Kodansha, Tokyo, 1995, pp. 67-70.

18. Mubarak, M. S. "Electrochemical Reduction of 2-Thiophenecarbonyl Chloride at Carbon and Mercury Cathodes in Acetonitrile" J. Electroanal. Chem. Interfacial Electrochem. 1995, 394, 239-243.

19. Mubarak, M. S.; Peters, D. G. "Electrochemical Reduction of 1,8-Dibromo- and 1,8-Diiodooctane and of 1,10-Dibromo- and 1,10-Diiododecane at Carbon Cathodes in Dimethylformamide" J. Electrochem. Soc., 1996, 143, 3833 - 3838.

20. Mubarak, M. S.; Peters, D.G. "Electrochemical Reduction of Mono-and Dihalothiophenes at Carbon Cathodes in Dimethylformamide. First Example of an Electrolytically Induced Halogen Dance" J.Org. Chem. 1996, 61, 8074-8078.

21. Mubarak, M. S.; Peters, D. G. "Electrochemical Reduction of Mono-and Dihalopyridines at Carbon Cathodes in Dimethylformamide" J. Electroanal. Chem. Interfacial Electrochem., 1997, 425, 13 –17.

22. Mubarak, M. S.; Peters, D. G. "Electrochemical Reduction of Di-, Tri-, and Tetrahalobenzenes at Carbon Cathodes in Dimethylformamide. Evidence for a Halogen Dance During the Electrolysis of 1,2,4,5-Tetrabromobenzene" J. Electroanal. Chem. Interfacial Electrochem. 1997, 435, 47-53.

23. Attari, M. H.; Mubarak, M. S.; and Khalili, F. I. "Preparation and Characterization of Some Tetradentate Schiff Bases and Their Complexes with Co(II), Ni(II), and Cu(II)". Synth React. Inorg. Met.- Org. Chem. 1997, 27, 1-16.

24. Ebraheem, K. A. K.; Mubarak, M. S.; Yassien, Z. J.; and Khalili, F. “Chelation Properties of Poly(8-hydroxyquinoline 5,7-diylmethylene) towards some Trivalent Lanthanide Metal Ions. Solvent Extraction and Ion Exchange, 1998, 16, 637- 649.

25. Mubarak, M. S.; Pagel M.; Marcus, L. M.; and Peters D. G. "Formation of 2-(3'-Oxocyclohexyl)-2-cyclohexene-1-one via Reduction of. 2-Cyclohexene-1-one with Electrogenerated Nickel(I) Salen" J. Org. Chem1998, 63, 1319-1322.

26. Mubarak M. S.; Inroduction to Chemistry, a text book in Arabic publishedby King Saud University, Saudi Arabia, 1998.

27. Alleman, K. S.; Samide, M. J.; Peters, D. G.; and Mubarak, M.S.,"Catalytic Reduction of Organohalogen Compounds with Electrogenerated Homogeneous-Phase and Polymer-Bound Cobalt(I) and Nickel(I) Salen" In Current Topics in Electrochemistry, J. O M. Bockris, E. J. Cairns, M. Forment, Z. Galus, Y. Ito, S. Trasatti, and T. J. Vander Noot, eds., Research Trends, Trivandrum, India, 1998.

28. Mubarak, M. S.; Peters, D. G. "Addition to Activated Olefins of  RadicalsFormed from Reaction of Alkyl Halides with Electrogenerated Ni(I) Salen".  J. Saudi Chem. Soc. 1999, 3, 135-146.

29. Sweiss, A. F.; Mubarak, M. S. "Synthesis and Characterization of Some 1,2-Disubstituted Ethenediol Diesters", J. Saudi Chem. Soc. 2000, 4(1), 95-102.

30. Al-Sau'd, K. A.; Khalili, F. I.; and Mubarak, M. S. "Preparation and Characterization of New Oxadiazole Derivatives and their Complexes with Some Metal Ions" J. Saudi. Chem. Soc. 2000, 4(2), 143-152.

31. Ebraheem, K. A. K.; Mubarak, M. S.; Yassien, Z. J.; and Khalili, F. "Chelation Properties of Poly(8-hydroxyquinoline 5,7-diylmethelene) Crosslinked with Bisphenol-A Towards La(III), Ce(III), Nd(III), Sm(III), and Gd(III) Ions” Separation Science and Technology, 2000, 35(13), 2115-2125.

32. Mubarak, M. S. and Peters, D. G. “Survey of the Electrochemical Behavior of Chlorinated Pyrazines, Quinoxalines, and Pyridazines at Carbon and Mercury Cathodes”, J. Electroanal. Chem. 2001, 507(1-2), 110-117.

33. Ji. C., Mubarak, M. S., Peters, D. G., Karty, J. A., and Reilly, J. P. “Direct and Catalytic Reduction of 2,6-Bis(chloromethyl)pyridine at Carbon Cathodes in Acetonitrile”, Reactive Intermediates in Organic and Biological Electrochemistry: Proceedings of the Symposium in Honor of the Late Professor Eberhard Steckhan, D. G. Peters, H. J. Schäfer, M. S. Workentin, and J. –I. Yoshida, eds., The Electrochemical Society, Inc., Pennington, New Jersey, 2001, pp. 85-88.

34. Fang, D. M.; Peters, D. G.; and Mubarak, M. S. “Catalytic Reduction of 6  Bromo-1-hexene by Nickel(I) Salen Electrogenerated at Glassy Carbon Cathodes in Acetonitrile”, J. Electrochem. Soc. 2001, 148(12), E464-E467.