The International Online Journal of Cancer & Therapeutics is a peer-reviewed open acess journal that publishes original research articles as well as review articles in all areas of Oncology. this practical journal also includes information on new products, new therapies and patient management, as well as reviews of the latest research. Cancer is a complex problem. The international effort to understand and control it involves clinicians trained in many branches of medicine and scientists from most biological disciplines, chemistry, pharmaceutical and physical sciences The International Online Journal of Cancer & Therapeutics exists to serve the needs of this diverse community, providing a forum for prompt communication of original and innovative research findings that have relevance to understanding the etiology of cancer and to improving the treatment and survival of patients.

The journal publishes important original studies, reviews, and perspectives within the major topic areas of biology of premalignancy, risk factors and risk assessment, early detection research, immunoprevention, and chemopreventive and other interventions, including the basic science behind them. This journal comprises preclinical, clinical and translational research, with special attention given to molecular discoveries and an emphasis on building a translational bridge between the basic and clinical sciences. Main focuses of interest include: systemic anticancer therapy (with specific interest on molecular targeted agents and new immune therapies), randomized trials (including negatives ones), top-level guidelines, and new fields currently emerging as key components of personalized medicine, such as molecular pathology, bioinformatics, modern statistics, and biotechnologies. Radiotherapy, surgery and pediatrics manuscripts can be considered if they display a clear interaction with one of the fields above or are paradigm-shifting.

Oncology is the diagnosis and treatment of cancers,including breast,prostate,colon,lung and ovarian cancers as well as brain tumors,leukemia,lymphoma and many other types of cancer.. A doctor who works in the field of oncology is called an oncologist. The primary regions of oncology are radiation, which is worried with radiation treatment, or radiotherapy; surgical, which is contained specialists who spend significant time in tumor evacuation; therapeutic, which manages disease drugs, including chemotherapy; and interventional, which includes interventional radiologists who have some expertise in insignificantly obtrusive picture guided tumor treatment.




Ebubekir Dirican

Assistant Doctor

Ebubekir Dirican is currently working as a Assistant  Dr. at Marmara  university, department of medical biology istanbul, Turky since February 2012. He has published 23 articles in national and international journals. He has scientific membership at EACR.

  • Cancer Biology, Cancer
  • Genotoxicity
  • Chromosomes, Genetics, Molecular Genetics,
  • Tumors, Micronucleus, Mutagenesis, Cytogenetics,
  • DNA Damage, Mutagenicity, Cytotoxicity, Genetic Toxicology,
  • Genotoxicology, In vitro Toxicology, Biomarkers,
  • Molecular Toxicology, Mutation, Cell Culture,,
  • Oxidative Stress Biomarkers, DNA, PCR, DNA Replication,
  • Gene Expression, Toxicological Analysis,
  • Comet Assay, Micronucleus Tests, Bioinformatics

1. Ebubekir Dirican: Kanserde Aspirin Kullanımının Önemi.

2. Ebubekir Dirican: Identification of PIK3CA Mutation and Expression by Bioinformatic Analysis in Breast Cancer.

3. Mustafa Akkiprik, Ebubekir Dirican, Gökçe Güllü Amuran, Ayşe Özer: Kanserde Genetik Üstü (Epigenetik) Mekanizmalar.

4. Ebubekir Dirican: Focus on Candidate Genes in Molecular Genetics Analyses for Breast Cancer Treatment.. Tumor research 03/2017; 3(119).

5. Ebubekir Dirican, Mustafa Akkiprik: High Resolution Melting Method in Molecular Diagnostics and Their Clinical Importance. DOI:10.5152/clinexphealthsci.2017.104

6. Ebubekir Dirican: THE IMPORTANCE OF PI3K SIGNALING PATHWAY IN BREAST CANCER DIAGNOSIS AND TREATMENT. Turkish Journal of Biochemistry 01/2017; 41(4):14.

7. Ebubekir Dirican, Mustafa Akkiprik: Phosphatidylinositol 3-kinase regulatory subunit 1 and phosphatase and tensin homolog as therapeutic targets in breast cancer. Tumor Biology 01/2017; 39(3)., DOI:10.1177/1010428317695529

8. Ebubekir Dirican, Mustafa Akkiprik: Functional and clinical significance of SALL4 in breast cancer. Tumor Biology 07/2016; 37(9)., DOI:10.1007/s13277-016-5150-7

9. Ebubekir Dirican: LETTER to the EDITOR: Mutations in PIK3CA Sensitize Breast Cancer Cells to Physiologic Levels of Aspirin. Asian Pacific journal of cancer prevention: APJCP 06/2016; 17(5):2731., DOI:10.7314/APJCP.2016.17.5.2731

10. Ebubekir Dirican, Mustafa Akkiprik, Ayşe Özer: Mutation distributions and clinical correlations of PIK3CA gene mutations in breast cancer. Tumor Biology 02/2016; 37(6)., DOI:10.1007/s13277-016-4924-2

11. Ebubekir Dirican, Zehra Kaya, Gokce Gullu, Irem Peker, Tolga Ozmen, Bahadir M Gulluoglu, Handan Kaya, Ayse Ozer, Mustafa Akkiprik: Detection of PIK3CA gene mutations with HRM analysis and association with IGFBP-5 expression levels in breast cancer. Asian Pacific journal of cancer prevention: APJCP 11/2014; 15(21):9327-33., DOI:10.7314/APJCP.2014.15.21.9327

12. Ebubekir Dirican, Hasan Turkez: In vitro studies on protective effect of Glycyrrhiza glabra root extracts against cadmium-induced genetic and oxidative damage in human lymphocytes. Cytotechnology 01/2013; 66(1)., DOI:10.1007/s10616-012-9531-5

13. Hasan Turkez, Umit Incekara, Adem Güner, Elanur Aydin, Ebubekir Dirican, Basak Togar: The cytogenetic effects of the aqueous extracts of migratory locust ( Locusta migratoria L.) in vitro. Toxicology and Industrial Health 08/2012; 30(3)., DOI:10.1177/0748233712452610

14. Ebubekir Dirican, Hasan Turkez: Thymbra spicata l. modulates chromium (iii) chloride-induced genetic and oxidative damage in vitro. Fresenius Environmental Bulletin 06/2012; 21(6):1480-1485.

15. Ebubekir Dirican, Hasan Turkez: Genotoxıc Effect Of Beryllıum Chlorıde And Protectıve Role Of Crataegus Oxyacantha L. (Hawthorn) Fruıt Extract In Vıtro. Fresenius Environmental Bulletin 06/2012; 21(6A):1578-1582.

16. Hasan Turkez, Fatime Geyikoğlu, Ebubekir Dirican, Abdulgani Tatar: In vitro studies on chemoprotective effect of borax against aflatoxin B1-induced genetic damage in human lymphocytes. Cytotechnology 04/2012; 64(6)., DOI:10.1007/s10616-012-9454-1

17. Ebubekir Dirican, Hasan Turkez, Başak Toğar: Modulatory effects of Thymbra spicata L. different extracts against the mercury induced genotoxicity in human lymphocytes in vitro. Cytotechnology 12/2011; 64(2):181-6., DOI:10.1007/s10616-011-9406-1

18. Basak Togar, Hasan Turkez, Abdulgani Tatar, Ismet Kirkpinar, Ahmet Hacimuftuoglu, Fatime Geyikoglu, M Sait Keles, Ebubekir Dirican: The genotoxic potentials of some atypical antipsychotic drugs on human lymphocytes. Toxicology and Industrial Health 09/2011; 28(4):327-33., DOI:10.1177/0748233711410919

19. Hasan Türkez, Ebubekir Dirican, Elanur Aydın, Başak Toğar, Kübra Çelik: Dermatocarpon intestiniforme (A Lichen) Modulates Aflatoxin B1 Induced Genetic and Oxidative Damage In Vitro.

20. Hasan Türkez, Hasan Gürbüz, Elanur Aydin, Ali Aslan, Ebubekir Dirican: The evaluation of the genotoxic and oxidative damage potentials of Ulothrix tenuissima (Kutz.) in vitro. Toxicology and Industrial Health 06/2011; 28(2):147-51., DOI:10.1177/0748233711407957

21. Hasan Turkez, Ebubekir Dirican: A modulator against mercury chloride-induced genotoxic damage: Dermatocarpon intestiniforme (L.). Toxicology and Industrial Health 05/2011; 28(1):58-63., DOI:10.1177/0748233711404036

22. Gul M, Dogan E, Kirecci E, Ucmak H, Dirican E, Karadag A. Serratia ficaria isolated from sputum specimen. Acta Microbiol Immunol Hung. 2011 Sep;58(3):235-8.